Knowledge and Awareness of Medication-Related Osteonecrosis of the Jaw Among Dental Practitioners in Mumbai: A Questionnaire-Based Survey DOI Open Access

Murtaza A Shapurwala,

Viraj Kharkar, Saudamini More

et al.

Cureus, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 26, 2024

Osteonecrosis of the jaw resulting from adverse effects medical treatments is known as medication-related osteonecrosis jaws (MRONJ). The knowledge dental professionals about this condition crucial in addressing it on a regional and global scale. This study aims to assess awareness MRONJ among practitioners Mumbai. descriptive cross-sectional utilized web-based questionnaire comprising 21 questions distributed postgraduate students at colleges, hospitals, private practices A total 403 dentists participated survey, with 85% familiar condition. significantly (p < 0.05) higher proportion clinicians over 20 years experience those specializing oral maxillofacial surgery were aware indications for bisphosphonate drugs. About 53% surgeons 57.7% participants more than that antiangiogenic drugs are used breast cancer treatment. However, their use lung was only 21%. Although term MRONJ, affecting disease, well its clinical radiographic presentations, inadequate. Awareness treatment strategies recent advances particularly lacking general other specialists apart (OMFS). Practitioners also identified lack an interdisciplinary approach. There clear need enhanced education subject, which can be achieved by conducting surveys, conferences, seminars.

Language: Английский

Clinical and Histological Evaluation of Jaw Osteonecrosis Unrelated to Anti-Bone Resorption Drugs DOI Creative Commons
Cinzia Casu, Andrea Butera, Andrea Scribante

et al.

Oral, Journal Year: 2025, Volume and Issue: 5(2), P. 29 - 29

Published: April 24, 2025

Medication-related osteonecrosis of the jaw (MRONJ) is a multifactorial condition defined as an adverse drug reaction that results in progressive jawbone destruction and necrosis individuals treated with certain medications, occurring without history prior radiotherapy. These drugs are mainly bisphosphonates, denosumab, other bone-modifying agents, anti-angiogenic agents such anti-endothelial growth factor, tyrosine kinase inhibitors, proteins classified mammalian targets rapamycin. The diagnosis MRONJ based on clinical (exposed jawbone, fistula pus, hyperplasia mucosa overlying necrotic bone tissue) radiological evaluation. We report four cases evidence unrelated to use antiresorptive or agents. In two instances, histological microbiological was also found (high concentration Actinomyces, microbe most commonly oral sites affected by MRONJ). atypical reported highlight possibility other, previously undocumented, may contribute development ONJ

Language: Английский

Citations

0
The Association of Systemic and Mandibular Bone Mineral Density in Postmenopausal Females with Osteoporosis DOI Creative Commons

Ioana Duncea,

Cecilia Bacali, Smaranda Buduru

et al.

Medicina, Journal Year: 2024, Volume and Issue: 60(8), P. 1313 - 1313

Published: Aug. 14, 2024

Background/Objectives: Osteoporosis is a common general disease that mostly affects the skeletal system, including jawbone. There link between systemic and mandibular osteoporosis. This study aimed at assessing association (lumbar spine L1–L4, femoral neck, total hip) bone mineral density (BMD) mandible BMD sites in Romanian postmenopausal females. Methods: A of 97 menopausal patients were studied, 62 with osteoporosis 35 females no For each patient, dual-energy X-ray absorptiometry (DXA) assessments mandible, proximal femur, hip, lumbar (L1–L4) performed. Mandibular measurements performed using distal forearm software, followed by manual analysis after contour was defined case. Results: Comparing control groups, there significant differences examined location. The (1.125 ± 0.181506 g/cm2) group considerably smaller than (1.35497 0.244397 g/cm2). Correlations different significant: neck (r = 0.738, p < 0.0001), hip 0.735, 0.506, 0.891, 0.482, 0.466, 0.0001). Conclusions: correlations spine, BMD, suggesting density. locations may help predict probability

Language: Английский

Citations

1
Balancing Innovation and Proven Techniques in Oral and Maxillofacial Surgery DOI Creative Commons
Karolina Walczyńska-Dragon, Maciej Chęciński

Surgeries, Journal Year: 2024, Volume and Issue: 5(3), P. 774 - 777

Published: Sept. 5, 2024

The field of oral and maxillofacial surgery is continuously evolving, with ongoing advancements in surgical techniques, materials, pharmacological approaches that enhance patient outcomes [...]

Language: Английский

Citations

0
An assessment of the oral health status and dental care treatment needs of oncology patients receiving bone modifying agents DOI
Harriet Byrne, Richeal Ní Ríordáin, Michael Cronin

et al.

Oral Surgery Oral Medicine Oral Pathology and Oral Radiology, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 1, 2024

Language: Английский

Citations

0
Knowledge and Awareness of Medication-Related Osteonecrosis of the Jaw Among Dental Practitioners in Mumbai: A Questionnaire-Based Survey DOI Open Access

Murtaza A Shapurwala,

Viraj Kharkar, Saudamini More

et al.

Cureus, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 26, 2024

Osteonecrosis of the jaw resulting from adverse effects medical treatments is known as medication-related osteonecrosis jaws (MRONJ). The knowledge dental professionals about this condition crucial in addressing it on a regional and global scale. This study aims to assess awareness MRONJ among practitioners Mumbai. descriptive cross-sectional utilized web-based questionnaire comprising 21 questions distributed postgraduate students at colleges, hospitals, private practices A total 403 dentists participated survey, with 85% familiar condition. significantly (p < 0.05) higher proportion clinicians over 20 years experience those specializing oral maxillofacial surgery were aware indications for bisphosphonate drugs. About 53% surgeons 57.7% participants more than that antiangiogenic drugs are used breast cancer treatment. However, their use lung was only 21%. Although term MRONJ, affecting disease, well its clinical radiographic presentations, inadequate. Awareness treatment strategies recent advances particularly lacking general other specialists apart (OMFS). Practitioners also identified lack an interdisciplinary approach. There clear need enhanced education subject, which can be achieved by conducting surveys, conferences, seminars.

Language: Английский

Citations

0