Antibiotics,
Journal Year:
2024,
Volume and Issue:
13(1), P. 76 - 76
Published: Jan. 13, 2024
Salmonella
is
a
major
foodborne
pathogen
and
leading
cause
of
gastroenteritis
in
humans
animals.
highly
pathogenic
encompasses
more
than
2600
characterized
serovars.
The
transmission
to
occurs
through
the
farm-to-fork
continuum
commonly
linked
consumption
animal-derived
food
products.
Among
these
sources,
poultry
products
are
primary
contributors,
followed
by
beef,
pork,
fish,
non-animal-derived
such
as
fruits
vegetables.
While
antibiotics
constitute
treatment
for
salmonellosis,
emergence
antibiotic
resistance
rise
multidrug-resistant
(MDR)
strains
have
highlighted
urgency
developing
alternatives.
Effective
infection
management
necessitates
comprehensive
understanding
pathogen’s
epidemiology
dynamics.
Therefore,
this
review
focuses
on
epidemiology,
sources
infection,
risk
factors,
dynamics,
host
range
serotypes.
This
also
investigates
disease
characteristics
observed
both
animals,
resistance,
pathogenesis,
potential
strategies
control
emphasizing
most
recent
antibiotic-alternative
approaches
control.
Poultry Science,
Journal Year:
2024,
Volume and Issue:
103(5), P. 103655 - 103655
Published: March 16, 2024
To
develop
effective
antibiotics
alternatives
is
getting
more
and
important
to
poultry
healthy
production.
The
study
investigated
the
effects
of
a
microencapsulated
essential
oils
organic
acids
preparation
(EOA)
on
growth
performance,
slaughter
nutrient
digestibility
intestinal
microenvironment
broilers.
A
total
624
1-day-old
male
Arbor
Acres
broilers
were
randomly
divided
into
6
groups
including
control
group
(T1)
fed
with
basal
diet,
antibiotic
(T2)
supplemented
diet
45
mg/kg
bacitracin
methylene
disalicylate
(BMD),
4
inclusion
levels
EOA-treated
(T3,
T4,
T5,
T6
groups)
chickens
given
200,
400,
600,
800
mg
EOA/kg
respectively.
Results
showed
that
compared
control,
200
EOA
increased
average
daily
gain
(ADG)
body
weight
(ABW)
during
early
stage
(P
<
0.05).
addition
decreased
crypt
depth
ileum
0.05),
but
villus
height
ratio
was
by
at
400
d
21
Compared
dietary
600
lipase
activity
in
duodenum
Increased
lactic
acid
bacteria
population
found
cecal
digesta
higher
concentration
butyric
level
observed
42
RT-PCR
analysis
gene
expression
IL-1β,
COX-2
TGF-β4
while
only
IL-10,
TGF-β4,
Claudin-1,
ZO-1,
CATH-1,
CATH-3,
AvBD-1,
AvBD-9
AvBD-12
0.05)
control.
In
summary,
adding
could
improve
performance
through
improving
morphology,
increasing
digestive
enzymes
abundance
content,
barrier
function
as
well
maintaining
immune
homeostasis.
effect
induced
better
than
later
stage.
Overall,
product
might
be
an
alternative
for
broiler
industry.
Poultry Science,
Journal Year:
2025,
Volume and Issue:
unknown, P. 105056 - 105056
Published: March 1, 2025
This
study
investigated
the
effects
of
astaxanthin
(AST)
supplementation
in
drinking
water
on
growth
performance,
intestinal
barrier
function,
and
cecal
microbiota
broilers
challenged
with
Salmonella
Enteritidis.
During
20-day
experiment,
two
hundred
forty
1-day-old
male
Arbor
Acres
birds
were
randomly
assigned
into
a
2
×
factorial
design
four
groups:
non-challenged
control
(CON),
an
S.
Enteritidis-challenged
group
(SA),
receiving
AST
treatment
(AST),
(SA+AST).
Each
comprised
six
replicate
groups,
groups
inoculated
Enteritidis
from
day
to
4.
The
results
indicated
that
infection
significantly
reduced
average
daily
feed
intake
(ADFI)
adversely
affected
gain
(ADG)
conversion
ratio
(FCR)
by
20.
improved
FCR.
While
did
not
affect
ileal
mucosa
antioxidation,
it
decreased
villus
height
height-to-crypt
depth
(VCR),
downregulated
mRNA
expression
ZO-1
Occludin.
However,
enhanced
antioxidant
capacity
(T-AOC),
increased
VCR
ileum,
notably
upregulated
MUC2
levels,
particularly
mitigating
adverse
crypt
depth.
Furthermore,
both
α-
β-diversity
microbiota.
Infection
was
associated
changes
at
phylum
level,
including
significant
increases
Alistipes,
unclassified_f__Lachnospiraceae,
bacteria
Clostridia
UCG-014
grouping,
alongside
notable
decreases
Bacteroides,
Akkermansia,
Blautia,
Butyricicoccus.
abundance
norank_f__Ruminococcaceae
Lachnoclostridium
unclassified_f__Lachnospiraceae
group.
In
conclusion,
could
improve
performance
health
Frontiers in Animal Science,
Journal Year:
2025,
Volume and Issue:
6
Published: March 17, 2025
Background
The
high
rates
of
diarrhea,
mortality,
and
feed
conversion
ratio
(F/G)
among
weaned
piglets
have
significantly
hindered
the
development
pig
feeding
practices
in
Jinhua,
located
North
Xinjiang
region.
Saccharomyces
boulardii
cell
wall
polysaccharide
(SBWP)
is
a
probiotic
that
has
potential
to
enhance
gastrointestinal
immunity
health,
while
also
reducing
systemic
inflammation,
diarrhea
rates,
mortality.
This
study
investigates
effects
SBWP
on
performance,
immune
capacity,
antioxidant
mucosal
morphology
from
region,
through
28-day
trial.
Methods
A
total
64
male
Jinhua
piglets,
aged
28
days
with
mean
body
weight
4.23
±
0.53
kg,
were
utilized
this
study.
randomly
assigned
four
experimental
groups,
each
consisting
pens
per
pen,
based
varying
percentages
as
supplement.
supplementation
concentrations
for
groups
0%
(control
group),
0.2%,
0.5%,
1.0%
SBWP,
respectively.
Results
Compared
CON
group,
0.5%
demonstrated
increase
average
daily
intake
(ADFI)
gain
(ADG),
alongside
decrease
feed-to-gain
(F/G).
Additionally,
fecal
score
frequency
reduced,
no
mortality
recorded
these
which
represented
37.50%
reduction
compared
group.
In
terms
ileal
immunity,
reduced
pro-inflammatory
cytokines,
including
interleukin-1β
(IL-1β),
interleukin-6
(IL-6),
tumor
necrosis
factor-α
(TNF-α),
well
diamine
oxidase
(DAO).
Conversely,
both
exhibited
elevated
anti-inflammatory
cytokine
interleukin-10
(IL-10).
Furthermore,
addition
increased
secretory
immunoglobulin
(SIgA).
serum
had
TNF-α,
IL-1β,
IL-6
DAO.
Regarding
capacity
mucosa,
content
malondialdehyde
(MDA)
hydrogen
peroxide
(H
2
O
)
decreased,
catalase
(CAT),
glutathione
peroxidase
(GSH-Px),
(T-AOC)
increased,
superoxide
dismutase
(SOD)
activity
was
enhanced.
Lastly,
basal
diet
resulted
promotion
villus
height
crypt
depth
(VCR),
thereby
improving
mucosa.
conclusion,
growth
performance
northern
improved
by
0.5-1.0%
when
supplemented
diet.
enhancement
attributed
function,
enhanced
morphology,
inflammatory
factors
mucosa
serum.
Frontiers in Microbiology,
Journal Year:
2025,
Volume and Issue:
16
Published: April 9, 2025
Post-weaning
diarrhea
in
piglets
is
a
common
challenge
that
adversely
impacts
growth
performance
and
increases
mortality,
leading
to
severe
economic
losses.
Medium-chain
fatty
acids
(MCFA)
short-chain
(SCFA)
are
frequently
used
as
feed
additives
due
their
bioactive
properties.
This
study
evaluated
the
effects
of
two
different
blends
MCFA
SCFA
(VSM
VS
+
VM)
alternatives
zinc
oxide
(ZnO)
on
performance,
nutrient
digestibility,
oxidative
stress,
inflammatory,
gut
microbiota
composition
weaned
piglets.
A
total
108
(8.22
±
0.51
kg)
were
randomly
assigned
three
treatments:
control
(CON,
basal
diet
ZnO),
VSM
(basal
higher
lower
content)
VM
content).
Results
indicated
Both
VM,
can
replace
ZnO
relieve
evidenced
by
increased
average
daily
gain
(ADG)
decreased
ratio
(F/G)
1-15
days,
with
no
difference
final
body
weight
compared
CON
group.
Additionally,
dietary
supplementation
improves
anti-oxidative
anti-inflammatory
capacity
malondialdehyde
(MDA)
activity,
inhibited
proinflammatory
cytokine
tumor
necrosis
factor
α
(TNF-α)
interleukin
(IL-1β,
IL-17A)
secretion.
Further
showed
protective
effect
associated
restoring
barrier,
upregulating
abundances
Lactobacillus
Roseburia
Collectively,
combination
alleviated
modulated
inflammation,
supported
barrier
function
piglets,
offering
promising
alternative
ZnO,
showing
superior
effects.
Veterinary Research,
Journal Year:
2025,
Volume and Issue:
56(1)
Published: May 6, 2025
Abstract
Pullorum
disease,
caused
by
Salmonella
pullorum
(
S.
),
is
a
highly
contagious
illness
affecting
the
poultry
industry
.
Emerging
evidence
suggests
that
Artemisia
argyit
essential
oil
can
influence
composition
of
gut
microbes
in
host,
thereby
promoting
overall
health.
However,
specific
mechanisms
which
modulates
microbiota
to
combat
infection
remains
unclear.
This
study
explored
effectiveness
various
doses
preventing
chicks.
Our
findings
indicate
consuming
this
mitigate
intestinal
mucosal
barrier
damage
and
excessive
inflammatory
response
pullorum,
as
well
reverse
weight
loss
seen
infected
Additionally,
chicks
received
faecal
transplantation
(FMT)
from
donors
exhibited
notable
recovery
infections.
observed
protection
may
be
linked
modulation
microbiota.
Furthermore,
16S
rRNA
sequencing
revealed
an
increased
abundance
Lactobacillus
reuteri
L.
along
with
activation
Wnt/β-catenin
pathways,
played
critical
roles
enhanced
health
-infected
treated
oil.
In
summary,
these
highlight
dietary
inclusion
promotes
enrichment
,
offering
promising
strategy
for
treatment
prevention
disease
