Global surgery and climate change: how global surgery can prioritise both the health of the planet and its people

BMC Surgery, Journal Year: 2025, Volume and Issue: 25(1)

Published: Jan. 11, 2025

Climate change is an emerging global health crisis, disproportionately affecting low- and middle-income countries (LMICs) where outcomes are increasingly compromised by environmental stressors such as pollution, natural disasters, human migration. With a focus on promoting equity, Global Surgery advocates for expanding access to surgical care enhancing outcomes, particularly in resource-limited disaster-affected areas like LMICs. The healthcare industry—and more specifically, care—significantly contributes the carbon footprint, primarily through resource-intensive settings, i.e. operating rooms that generate greenhouse gases substantial medical waste. Therefore, efforts aimed at improving increase volumes may inadvertently exacerbate challenges vulnerable populations further contributing degradation. This predicament pronounced LMICs, who already suffer from disproportionate share of burden disease, demand surgery rising without corresponding resilient infrastructure. LMICs face double jeopardy inequity coupled with climate vulnerability. As movement positioned improve around world, has significant role envisioning ensuring sustainable future. initiatives must prioritise infrastructure both high-income (HICs) all while accounting unequal polluting contributions between HICs and, consequently, moral responsibilities moving forward. Moreover, targeting upstream causes poor urban perioperative levels, Surgery's interventions help reduce disease—avoiding preventable surgeries their footprints outset. Altogether, two matters social justice whose solutions synergistically centralise planet its most people.

Language: Английский

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Addressing the knowledge gap: How to bridge the gap and strengthen the health research ecosystem in Africa

Published: April 1, 2025

Language: Английский

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Chemoprevention of malaria with long-acting oral and injectable drugs: an updated target product profile

Malaria Journal, Journal Year: 2024, Volume and Issue: 23(1)

Published: Oct. 18, 2024

Abstract Malaria is preventable, but the burden of disease remains high with over 249 million cases and 608,000 deaths reported in 2022. Historically, most important protective interventions have been vector control chemopreventive medicines 50 children receiving seasonal malaria chemoprevention year 2023. Two vaccines are approved starting to be deployed, bringing additional protection for up 36 months. However, impact these currently available tools somewhat limited on various fronts. Vaccines exhibit partial efficacy, relatively costly, not accessible all settings. The challenges encountered barriers acceptability feasibility, including frequency dosing, lack options first trimester pregnancy women living HIV. Also, emergence resistance against concerning. To address limitations, a target product profile (TPP) proposed as road map guide innovation boost quest novel alternatives. This TPP describes ideal attributes, while acknowledging potential trade-offs that may needed. Critically, it considers populations at risk; primarily infants, children, pregnant women. elimination requires appropriate chemoprevention, only areas endemicity transmission, also lower transmission where immunity declining, well travellers from has eliminated. New should show acceptable safety tolerability, long efficacy. Formulations costs need support operational adherence, access, effectiveness. Next generation long-acting oral injectable drugs likely constitute backbone prevention. Therefore, perspectives front-line experts prevention, researchers, those involved drug development captured TPP. inclusive approach aims concentrating efforts aligning responses across community develop new transformative medicines.

Language: Английский

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Emerging public health strategies in malaria control: innovations and implications

Annals of Medicine and Surgery, Journal Year: 2024, Volume and Issue: 86(11), P. 6576 - 6584

Published: Sept. 19, 2024

Language: Английский

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Chitosan-based insecticide formulations for insect pest control management: A review of current trends and challenges

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: unknown, P. 135937 - 135937

Published: Sept. 1, 2024

Language: Английский

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