Association Between Weight-Adjusted Waist Index and Emphysema in Adults in the United States: A Cross-Sectional Study Involving 44,949 Participants DOI Creative Commons
Hui Cheng, Ziheng Yang, Jiateng Guo

et al.

Advances in respiratory medicine, Journal Year: 2024, Volume and Issue: 92(6), P. 472 - 484

Published: Nov. 21, 2024

Background: The relationship between obesity and respiratory diseases has been widely explored. In this context, the Weight-Adjusted Waist Index (WWI) emerged as a novel metric for assessing visceral fat. This study aims to evaluate association WWI risk of emphysema in U.S. population, by utilizing data from 2001–2018 National Health Nutrition Examination Survey (NHANES). Methods: A cross-sectional was conducted using NHANES 2001 2018. Logistic regression models were applied assess risk. Interaction subgroup analyses performed explore effect modifiers. Results: Our included total 44,949 American adults. results multivariable logistic analysis revealed an incidence emphysema. fully adjusted model, probability developing 1.5 times higher group with > 10.46 compared those ≤ 10.46, odds ratio [1.5 (1.1, 1.9), p = 0.003]. Subgroup showed stronger associations among males, non-Hispanic Whites, individuals hypertension. Furthermore, we used two-piece linear model found nonlinear emphysema, breakpoint at 12.5. Conclusions: findings indicate significant levels Larger-scale prospective studies are needed further role

Language: Английский

A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, 8-Week Pilot Study of Tuna-Byproduct-Derived Novel Supplements for Managing Cellular Senescence and Cognitive Decline in Perimenopausal and Postmenopausal Women DOI Creative Commons
Jintanaporn Wattanathorn, Wipawee Thukham-mee, Terdthai Tong-un

et al.

Antioxidants, Journal Year: 2025, Volume and Issue: 14(5), P. 520 - 520

Published: April 27, 2025

Due to the lack of clinical data, we aimed assess anti-cellular senescence and cognition-enhancing effects mechanisms novel tuna-byproduct-derived supplements. An 8-week, three-arm, randomized, double-blind, placebo-controlled parallel study was performed. A total 60 female perimenopausal postmenopausal women (45–60 years old) were randomly assigned placebo, low (2600 mg/day), high (6000 mg/day) doses supplement. The N100 P300 brain waves, working memory, serum levels MDA, SOD, CAT, GPx TNF-α, IL-6, eNOS, AChE, MAO, GABA-T, SIRT1, density Lactobacillus Bifidobacterium spp. in feces assessed before consumption every 4 weeks throughout period. telomere length phenolic compound DHA at end study. dose increased amplitude, length, whereas improved amplitudes N00 P300, latency, memory; suppressed GABA-T; GPx, IL-6 serum, further exhibiting an increase DHA. Therefore, supplement could be a potential remedy for managing cellular cognitive decline women; however, studies with larger sample sizes are required.

Language: Английский

Citations

0

Mung Bean Functional Protein Enhances Endothelial Function via Antioxidant Activity and Inflammation Modulation in Middle-Aged Adults: A Randomized Double-Blind Trial DOI Creative Commons
Supaporn Muchimapura, Wipawee Thukham-mee, Sophida Phuthong

et al.

Foods, Journal Year: 2024, Volume and Issue: 13(21), P. 3427 - 3427

Published: Oct. 28, 2024

This study examines the impact of mung bean (Vigna radiata) protein consumption on endothelial function in middle-aged adults, focusing antioxidant enzyme activity and anti-inflammatory markers. Mung beans have shown promise enhancing cardiovascular function, lowering blood pressure, improving lipid profiles, but underlying mechanisms these functions remain unclear. Conducted as a three-arm randomized, double-blind, placebo-controlled trial, this involved male female participants aged 45 to 60 assigned them consume either placebo or functional drink containing 10 15 g daily for six weeks. Vasodilation was assessed using flow-mediated dilation (FMD), oxidative stress markers, activity, inflammatory markers were measured at baseline after intervention. The results indicate that weeks significantly benefits healthy adults by reducing mediators’ expression. Additionally, increase brachial artery diameter following FMD indicates improved function.

Language: Английский

Citations

0

Association Between Weight-Adjusted Waist Index and Emphysema in Adults in the United States: A Cross-Sectional Study Involving 44,949 Participants DOI Creative Commons
Hui Cheng, Ziheng Yang, Jiateng Guo

et al.

Advances in respiratory medicine, Journal Year: 2024, Volume and Issue: 92(6), P. 472 - 484

Published: Nov. 21, 2024

Background: The relationship between obesity and respiratory diseases has been widely explored. In this context, the Weight-Adjusted Waist Index (WWI) emerged as a novel metric for assessing visceral fat. This study aims to evaluate association WWI risk of emphysema in U.S. population, by utilizing data from 2001–2018 National Health Nutrition Examination Survey (NHANES). Methods: A cross-sectional was conducted using NHANES 2001 2018. Logistic regression models were applied assess risk. Interaction subgroup analyses performed explore effect modifiers. Results: Our included total 44,949 American adults. results multivariable logistic analysis revealed an incidence emphysema. fully adjusted model, probability developing 1.5 times higher group with > 10.46 compared those ≤ 10.46, odds ratio [1.5 (1.1, 1.9), p = 0.003]. Subgroup showed stronger associations among males, non-Hispanic Whites, individuals hypertension. Furthermore, we used two-piece linear model found nonlinear emphysema, breakpoint at 12.5. Conclusions: findings indicate significant levels Larger-scale prospective studies are needed further role

Language: Английский

Citations

0