Dysphagia for medication in Parkinson’s disease

npj Parkinson s Disease, Journal Year: 2022, Volume and Issue: 8(1)

Published: Nov. 12, 2022

Abstract Dysphagia is common in Parkinson’s disease (PD) and assumed to complicate medication intake. This study comprehensively investigates dysphagia for its association with motor complications PD. Based on a retrospective analysis, two-dimensional graduated classification of was introduced differentiating swallowing efficiency safety. In subsequent prospective study, sixty-six PD patients underwent flexible endoscopic evaluation swallowing, which included the 2 tablets capsules different sizes. present nearly 70% predicted according MDS-UPDRS-part-IV linear regression model. Capsules tended be swallowed more efficiently compared tablets, irrespective size. A score ≥1 swallow-related-MDS-UPDRS-items can considered an optimal cut-off predict medication. Swallowing impairment oral may predispose complications.

Language: Английский

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Sarcopenic Dysphagia Revisited: A Cross-Sectional Study in Hospitalized Geriatric Patients

Nutrients, Journal Year: 2023, Volume and Issue: 15(12), P. 2662 - 2662

Published: June 7, 2023

Oropharyngeal dysphagia (OD) is a frequent finding in older patients with potentially lethal complications such as aspiration pneumonia, malnutrition, and dehydration. Recent studies describe sarcopenia causative factor for OD, which occasionally referred to “sarcopenic dysphagia” the absence of neurogenic etiology. In most previous on sarcopenic dysphagia, diagnosis was based only clinical assessment. this study, flexible endoscopic evaluation swallowing (FEES) used an objective method evaluate presence its association sarcopenia, pure dysphagia. retrospective cross-sectional 109 acute care geriatric hospital suspected OD received FEES examination bioimpedance analysis (BIA) routine. 95% had at least one neurological disease, 70% fulfilled criteria 45% displayed moderate or severe OD. Although prevalence high, there no significant between sarcopenia. Considering these results, both appear questionable. Further prospective are needed elucidate if merely epiphenomenon disease whether it plays role development

Language: Английский

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Oropharyngeal dysphagia

Elsevier eBooks, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 39

Published: Jan. 1, 2024

Language: Английский

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Flow analysis of a two-layered micropolar fluid in a catheterized oesophageal tube under the influence of a dilating amplitude: Application to pre-diagnosis of oesophageal motility disorder

Physica Scripta, Journal Year: 2024, Volume and Issue: 99(8), P. 085020 - 085020

Published: July 2, 2024

Abstract This study employs the Homotopy perturbation method to analyze behavior of immiscible, incompressible fluids within a cylindrical coaxial tube, focusing on scenarios relevant physiological fluid dynamics, particularly in catheterized oesophagus and similar biological systems. Adopting long-wavelength low Reynolds number approximations, two-layered model is proposed with micropolar core Newtonian periphery regions. Parameters such as velocity, flux, friction, pressure, impedance variations are formulated, under influence dilating wave amplitude. Generally, when catheter introduced, pressure rises. It further found that while falls increasing parameter, it rises coupling upon insertion. Thus feeding patients during catheter-assisted pre-diagnosis impractical due associated rise. Observations suggest complex profile bolus passage through broadening size. Additionally, exponentially increases size, influenced by parameters numbers, exhibiting higher than fluids. However, this underscores significant impact catheterization notably oesophageal two threefold. highlights critical role catheters altering flow characteristics, emphasizing need for careful medical intervention pre-diagnostic assessments.

Language: Английский

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European Survey: Dysphagia Management in Patients with Neuromuscular Diseases

Dysphagia, Journal Year: 2022, Volume and Issue: 37(5), P. 1279 - 1287

Published: Jan. 3, 2022

Language: Английский

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