Sustainable Enzymatic Production of Bioactive Compounds: From Designing to Bioavailability DOI Creative Commons
Raquel A. F. Neves, Maria H.L. Ribeiro

Compounds, Journal Year: 2024, Volume and Issue: 4(4), P. 708 - 728

Published: Nov. 25, 2024

This study evaluates the feasibility and effectiveness of using immobilized pectinase enzymes for juice processing to reduce cloudiness while preserving nutritional bioactive properties. The research is driven by increasing demand innovative food products that offer enhanced functionality health benefits. It focuses on development application biocatalysts in bioprocessing, specifically encapsulated a sol–gel matrix. Reaction parameters interaction between its primary substrate, pectin, were optimized through systematic experimentation. Optimal conditions established, achieving enzyme activity stability with 0.15 g lens-shaped capsules containing 10.0 mg/mL 24-well microplates as microreactors. Kinetic studies indicated improved substrate affinity after immobilization (Km = 0.115 mg/mL), particularly when magnetized (Kmi 0.041 mg/mL). Operational reusability assessments demonstrated potential extended use retaining higher residual fourth reuse cycle (155% > 75%). peach nectar successfully reduced increased release compounds, enhancing antioxidant anti-inflammatory activities, evaluated DPPH (2,2-diphenyl-1-picrylhydrazyl) assay albumin method, respectively. In vitro digestion revealed dynamic profile changes, highlighting impact bioprocessing bioavailability.

Language: Английский

Does Encapsulation Improve the Bioavailability of Polyphenols in Humans? A Concise Review Based on In Vivo Human Studies DOI Open Access
Ali Ali Redha, Chamali Kodikara, Daniel Cozzolino

et al.

Nutrients, Journal Year: 2024, Volume and Issue: 16(21), P. 3625 - 3625

Published: Oct. 25, 2024

Polyphenols offer an array of health benefits that can contribute to well-being. Nevertheless, their bioactivity be compromised due low bioavailability. Encapsulation has been explored as a strategy enhance the stability and bioavailability polyphenols. During encapsulation, polyphenols are protected from degradation by wall material acts protective coating. This coating shields harsh physiological conditions digestion, ensuring delivery intestine. However, majority evidence, particularly regarding after is derived in vitro studies. While these studies provide valuable preliminary insights, they cannot definitively confirm effects vivo inability accurately replicate complex gut microbial ecosystem. Consequently, this review seeks evaluate current evidence human elucidate efficacy encapsulation improving polyphenols'

Language: Английский

Citations

5
Obtention of stable neuroprotective extracts from orange by-products by gas-expanded liquids extraction (GXLE) and liposomal microencapsulation. DOI Creative Commons
Víctor M. Amador-Luna, Lídia Montero,

Pablo Mendoza-Orbaneja

et al.

Green Analytical Chemistry, Journal Year: 2025, Volume and Issue: 12, P. 100216 - 100216

Published: Jan. 31, 2025

Language: Английский

Citations

0
Bioactive Compounds in Active Food Packaging (ACP): Health and Safety Considerations DOI
Aeyaz Ahmad Bhat,

Anjuman Ayub,

Atif Khurshid Wani

et al.

Engineering materials, Journal Year: 2025, Volume and Issue: unknown, P. 335 - 357

Published: Jan. 1, 2025

Language: Английский

Citations

0
Encapsulating Myrtus communis essential oil in date kernel polysaccharides: An innovative approach to controlling Cryptolestes ferrugineus DOI Creative Commons
Abir Soltani,

Tasnim Djebbi,

Jouda Médiouni Ben Jemâa

et al.

Research Square (Research Square), Journal Year: 2025, Volume and Issue: unknown

Published: March 27, 2025

Abstract This study aimed to provide an overview of recent progress in utilizing polysaccharides derived from date kernels as raw materials for encapsulating Myrtus communis essential oil, investigating its potential effective approach insect control stored food products, particularly against Cryptolestes ferrugineus infesting semolina. Most studies this field have relied on single-method approaches, which are prone overconfidence and lack sufficient validation across repeated trials, raising concerns about their robustness. To address these limitations, research explores the use polysaccharide encapsulation a sustainable efficient strategy controlling pests storage, with focus enhancing stability efficacy oil-based treatments. oil was primarily composed α-pinene (43.94%). Encapsulation efficiency reached 35.7%, loading capacity 3.65%. The encapsulated caused 100% mortality complete emergence inhibition C. adults. Date kernel solution showed moderate attractancy (Class III), while microcapsules performed better IV). Encapsulated oils minimally affected semolina properties, whereas crude reduced protein by 2.32%, decreased ash 10.98%, increased moisture 2.56% after 45 days. highlights innovative valorizing pit waste extracting incorporating them into processes, offering dual benefit management development eco-friendly bio-pesticides. provides practical formulating pest agents, demonstrating resource-efficient practices agricultural applications.

Language: Английский

Citations

0
Enhancing cell viability and GABA production in fermented milk using fruit juice-coated alginate microencapsulated Lactiplantibacillus plantarum B7 during storage DOI
Sangkaran Pannerchelvan,

Louise Lorna Lanne Jawlan,

Helmi Wasoh

et al.

International Microbiology, Journal Year: 2025, Volume and Issue: unknown

Published: April 15, 2025

Language: Английский

Citations

0
Harnessing Jasminum Bioactive Compounds: Updated Insights for Therapeutic and Food Preservation Innovations DOI Creative Commons
Antonio Rescigno, Paolo Zucca, Stefania Peddio

et al.

Food Frontiers, Journal Year: 2025, Volume and Issue: unknown

Published: April 21, 2025

ABSTRACT The Jasminum genus, renowned for its aromatic flowers, has been used in traditional medicine across various cultures therapeutic properties. Recently, scientific interest focused on the bioactive compounds present species, highlighting their potential applications health and food preservation. This review evaluates phytochemical composition of emphasizing preservative roles while identifying research gaps. A comprehensive literature search was conducted using major databases, including PubMed, Scopus, Web Science, focusing studies from last two decades. includes peer‐reviewed articles that provide robust methodologies detailed results regarding biological activities species. Findings reveal is rich such as terpenoids, flavonoids, phenolic acids, contributing to significant antioxidant, anti‐inflammatory, antimicrobial, anticancer Scientific evidence supports uses, treating headaches infections. Additionally, extracts have shown promise natural preservatives due potent antimicrobial activity. However, identifies variability study a lack clinical trials, which limit generalizability application these findings. species possess diverse profile holds advancing preservation applications. Future should prioritize standardizing conducting trials validate efficacy. Bridging gap between knowledge modern science will unlock full multifaceted resource nutrition.

Language: Английский

Citations

0
A Comparative Analysis on Impact of Drying Methods on Metabolite Composition in Broccoli Microgreens DOI Creative Commons
Trina Ekawati Tallei,

Maghfirah Savitri,

Da-In Lee

et al.

LWT, Journal Year: 2024, Volume and Issue: 210, P. 116866 - 116866

Published: Oct. 1, 2024

Language: Английский

Citations

3
Encapsulation of W/O/W Acerola Emulsion by Spray Drying: Optimization, Release Kinetics, and Storage Stability DOI Creative Commons

Yen Thi Dang,

Hieu V. Tran,

Tuyen C. Kha

et al.

Foods, Journal Year: 2024, Volume and Issue: 13(10), P. 1463 - 1463

Published: May 9, 2024

Acerola (Malpighia emarginata DC.) is a sub-tropical and tropical fruit renowned for its high levels of vitamin C phenolic compounds, which offer health benefits. This study aimed to optimize the spray drying process by determining inlet outlet temperatures using response surface methodology (RSM) with central composite design. Additionally, it evaluate release kinetics in hydrophilic food simulation environment stability resulting powder under various storage temperatures. The RSM method determined optimal as 157 °C 91 °C, respectively. High-accuracy prediction equations (R2 ≥ 0.88) were developed moisture content (3.02%), yield (91.15%), encapsulation total polyphenol (61.44%), flavonoid (37.42%), (27.19%), predicted monolayer below 4.01%, according BET equation. exhibited good dissolution characteristics acidic showed greater when stored at 10 30 days, compared 35 45 °C.

Language: Английский

Citations

1
Insights into grape-derived health benefits: a comprehensive overview DOI Creative Commons
Marta Angela de Almeida Sousa Cruz, Monique de Barros Elias, Daniela Călina

et al.

Food Production Processing and Nutrition, Journal Year: 2024, Volume and Issue: 6(1)

Published: Dec. 3, 2024

Abstract Grapes, renowned for their diverse phytochemical composition, have long been recognized health-promoting properties. This narrative review aims to synthesize the current research on grapes, with a particular emphasis role in disease prevention and health enhancement through bioactive compounds. A comprehensive of peer-reviewed studies, including vitro , vivo clinical investigations, was conducted elucidate relationship between grape consumption outcomes. The highlights positive association intake decreased risk chronic diseases such as cardiovascular disease, type 2 diabetes, certain cancers. Notable components like resveratrol are emphasized neuroprotective antioxidative capabilities. Additionally, explores emerging impact grapes gut microbiota its implications metabolic immune function. updated underscores importance future fully leverage understand therapeutic potential grape-derived compounds, aiming refine dietary guidelines functional food formulations. Further translational studies expected clarify specific interactions impacts health. Graphical

Language: Английский

Citations

1
In Vitro Culture of Human Dermal Fibroblasts on Novel Electrospun Polylactic Acid Fiber Scaffolds Loaded with Encapsulated Polyepicatechin Physical Gels DOI Creative Commons
Eliza Miranda-Buendía, Gertrudis Hortensia González-Gómez, Alfredo Maciel-Cerda

et al.

Gels, Journal Year: 2024, Volume and Issue: 10(9), P. 601 - 601

Published: Sept. 20, 2024

Polyepicatechin (PEC) in a hydrogel has previously shown promise enhancing physiological properties and scaffold preparation. However, it remains unclear whether PEC-based fibers can be applied skin tissue engineering (STE). This study aimed to synthesize characterize electrospun PEC physical gels polylactic acid (PLA) scaffolds (PLAloadedPECsub) for potential use as constructs with human dermal fibroblasts (HDFs). was produced through enzymatic polymerization, confirmed by Fourier transform infrared (FTIR) spectroscopy. Scanning electron microscopy (SEM) demonstrated the feasibility of producing PLAloadedPECsub electrospinning. The metabolic activity viability HDFs cocultured indicate that is promising STE.

Language: Английский

Citations

0