Intensive Care Medicine – Paediatric and Neonatal, Journal Year: 2025, Volume and Issue: 3(1)

Published: April 7, 2025

Abstract Aim To explore ventilator settings, ventilation variables and parameters in critically ill pediatric patients across European Centers. Methods International, multicenter, prospective observational study, collecting data for 7 days from aged ≤ 12 years, requiring ventilatory support ≥ h. Primary endpoint was a set of key including tidal volume (V T ), respiratory rate (RR), peak mean airway pressure (Ppeak Pmean), positive end–expiratory (PEEP), the fraction inspired oxygen (FiO 2 ). Ventilator settings were compared neonates (aged < 1 month), infants (1 to months), toddlers 3 years) children (4 years), between with without acute distress syndrome (PARDS). Results Patients enrolment occurred 43 centers 11 countries, total 166 patients—mostly infants—included this analysis. The majority began invasive ventilation, while one–third started noninvasive (NIV) or high–flow nasal (HFNO). on NIV HFNO weaned within median [2–6], [2–4] days, respectively. In 22% patients, used following ventilation. V , RR FiO varied age groups, pressures higher PARDS patients. Conclusions cohort, parameters, individual patient groups. Larger studies are needed confirm variability, associations practices clinical outcomes, assess temporal geo–economic differences.

Language: Английский