Late presentation and suboptimal treatment of breast cancer among Syrian refugees: a retrospective study

Journal of International Medical Research, Journal Year: 2021, Volume and Issue: 49(5)

Published: May 1, 2021

Objectives The crisis in Syria has had a profound impact on the entire region. In this study, we report patterns of presentation and management Syrian patients with breast cancer treated at our institution. Methods We retrospectively collected data refugees for over past 10 years center. Management was compared against approved clinical practice guidelines. Results A total 113 were eligible included. median age (range) diagnosis 47 (21–84) most women presented locally advanced or metastatic disease (n = 74, 65.5%). Breast-conserving surgery reconstruction performed 27 (33.8%) 11 (35.4%) patients, respectively. Only few received targeted (35.5%) endocrine therapy (30.0%). total, 37 (32.7%) considerable deviations from institutional treatment guidelines worse outcomes. Conclusions present late, have more advanced-stage disease, are likely to receive delayed suboptimal therapy. An international systematic approach care among such vulnerable populations is urgently needed.

Language: Английский

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Burden of prostate cancer in the Middle East: A comparative analysis based on global cancer observatory data

Cancer Medicine, Journal Year: 2023, Volume and Issue: 12(23), P. 21419 - 21425

Published: Nov. 6, 2023

Abstract Background Prostate cancer represents a significant global health issue, yet our understanding of its impact in the Middle East remains limited. This study aimed to assess incidence and mortality prostate East, compare these rates those Europe North America. Materials Methods We utilized 2020 Global Cancer Observatory data, compiling 20 Eastern countries. calculated mortality‐to‐incidence ratios (MIR) compared age‐standardized rate (ASIR) MIR between combined regions America Europe. The countries were further stratified based on Human Development Index (HDI) income level for additional analysis. Results In 2020, documented an estimated 51,649 new diagnoses, accounting 3.7% cases. Despite significantly lower ASIR with (10.50 vs. 21.50, p = 0.0087), region had higher (12.35 3.00, 0.0476). When HDI or levels, there was no difference MIRs; however, trend increasing decreasing ( 0.028) levels 0.016) observed. Conclusions incidence, analysis showed These findings underscore unique challenges posed by emphasize necessity tailored strategies address this pressing public issue.

Language: Английский

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Cancer care in times of conflict: cross border care in Pakistan of patients from Afghanistan

ecancermedicalscience, Journal Year: 2020, Volume and Issue: 14

Published: March 5, 2020

Armed conflict in Afghanistan has continued for close to 40 years and devastated its health infrastructure.The lack of a cancer care infrastructure meant that many Afghans seek neighbouring countries, like Pakistan.There remains significant empirical data on the new therapeutic geographies contemporary conflicts.This retrospective single centre study explores clinical Afghan patients who were treated at Shaukat Khanum Memorial Cancer Hospital Research Centre (SKMCH&RC) Lahore, Pakistan over 22-year-period (1995 2017) covering major periods relative peace.Data was available 3,489 received treatment SKMCH&RC.The mean age presentation 42.7 years, 60% men.30.2% came from Kabul Nangarhar districts Afghanistan, which have relatively short travel times Pakistan, but all parts migrated SKMCH&RC treatment.Overall, 34.1% diagnosed with upper gastrointestinal malignancies 55.7% presented late stage III/IV cancer.A wide range treatments provided, 25.4% receiving combination chemotherapy radiation treatment.52.7% lost follow-up.Outcomes more favourable children cancer, 42% whom had complete response therapy.Complex migration patterns, mixed political economies (refugees, forced unforced migrants) models must be adapted realities rather than notional international standards reflect long-term creates.This requires domestic (e.g., United Nations High Commissioner Refugees) policy practises providing today's ecosystems frequently cross national borders.

Language: Английский

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Interruption of cancer screening services due to COVID-19 pandemic: lessons from previous disasters

Preventive Medicine Reports, Journal Year: 2021, Volume and Issue: 23, P. 101399 - 101399

Published: May 17, 2021

To review the scientific literature seeking lessons for COVID-19 era that could be learned from previous health services interruptions affected delivery of cancer screening services. A systematic search was conducted up to April 17, 2020, with no restrictions on language or dates and resulted in 385 articles. Two researchers independently assessed list discussed any disagreements. Once a consensus achieved each paper, those selected were included review. Eleven articles included. Three studies based Japan, two United States, one South Korea, Denmark, remaining four offered global perspective due natural human-caused disasters. No covered an interruption pandemic. The main themes identified reviewed coordination, communication, resource availability patient follow-up. Lessons applied context are coordination involving partners across sector is essential optimize resources resume services, making them more resilient while preparing future interruptions. Communication general population about how has screening, measures taken mitigate it safely re-establish recommended. Use mobile systems reach patients who not accessing application resource-stratified guidelines important considerations. More research needed explore best strategies suspending, resuming sustaining programs, preparedness disruptions, adapted diverse care systems.

Language: Английский

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Factors Affecting the Cervical Cancer Screening Behaviors of Japanese Women in Their 20s and 30s Using a Health Belief Model: A Cross-Sectional Study

Current Oncology, Journal Year: 2022, Volume and Issue: 29(9), P. 6287 - 6302

Published: Aug. 31, 2022

In recent years, the incidence and mortality rates of cervical cancer (CC) have increased among young women. Cervical screening (CCS) is crucial to reducing CC in a country such as Japan, where it challenging raise HPV vaccination rates. The purpose this study was identify psychological personal characteristics relating CCS participation people by using Health Belief Model (HBM). For cross-sectional study, an internet survey conducted between February-March 2018. Based on HBM characteristics, χ2 tests logistic analyses were used factors influencing CCS. Responses obtained from 816 women their 20s 30s analysis. HBM-based odds ratios significantly higher for "cues screening" "barriers at time screening", while before showed lower ratios. On other hand, found that presence children having regular health checkups affected attributes significant decision-making. Therefore, important create proactive measures encourage younger undergo medical examinations.

Language: Английский

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