Life,
Journal Year:
2024,
Volume and Issue:
14(7), P. 856 - 856
Published: July 8, 2024
Obesity
is
an
important
condition
affecting
the
quality
of
life
numerous
patients
and
increasing
their
associated
risk
for
multiple
diseases,
including
tumors
immune-mediated
disorders.
Inflammation
appears
to
play
a
major
role
in
development
obesity
represents
central
point
activity
cellular
humoral
components
adipose
tissue.
Macrophages
key
as
main
component
tissue
regulating
chronic
inflammation
modulating
secretion
differentiation
various
pro-
anti-inflammatory
cytokines.
also
involves
series
signaling
pathways
that
might
represent
focus
new
therapies
interventions.
Weight
loss
essential
decreasing
cardiometabolic
risks
degree
inflammation;
however,
latter
can
persist
long
after
excess
weight
lost,
involve
changes
macrophage
phenotypes
ensure
metabolic
adjustment.
A
clear
understanding
pathophysiological
processes
interplay
between
lead
better
comorbidities
may
future
targets
treatment
obesity.
Reviews in Endocrine and Metabolic Disorders,
Journal Year:
2023,
Volume and Issue:
24(5), P. 809 - 823
Published: March 17, 2023
Obesity
is
the
most
extended
metabolic
alteration
worldwide
increasing
risk
for
development
of
cardiometabolic
alterations
such
as
type
2
diabetes,
hypertension,
and
dyslipidemia.
Body
mass
index
(BMI)
remains
frequently
used
tool
classifying
patients
with
obesity,
but
it
does
not
accurately
reflect
body
adiposity.
In
this
document
we
review
classical
new
classification
systems
phenotyping
obesities.
Greater
accuracy
accessibility
to
composition
techniques
at
same
time
increased
knowledge
use
factors
leading
a
more
refined
obesity.
It
incorporate
these
advances
into
routine
clinical
practice
better
diagnose
overweight
optimize
treatment
living
Journal of Obesity & Metabolic Syndrome,
Journal Year:
2023,
Volume and Issue:
32(1), P. 1 - 24
Published: March 22, 2023
The
goal
of
the
8th
edition
Clinical
Practice
Guidelines
for
Obesity
is
to
help
primary
care
physician
provide
safe,
effective
patients
with
obesity
by
offering
evidence-based
recommendations
improve
quality
treatment.
Committee
comprised
individuals
multidisciplinary
expertise
in
management.
A
steering
board
seven
experts
oversaw
entire
project.
Recommendations
were
developed
as
answers
key
questions
formulated
patient/problem,
intervention,
comparison,
outcomes
(PICO)
format.
underwent
multi-level
review
and
cross-checking
received
endorsement
from
relevant
scientific
societies.
This
guidelines
includes
criteria
diagnosing
obesity,
abdominal
metabolic
syndrome;
evaluation
its
complications;
weight
loss
goals;
treatment
options
such
diet,
exercise,
behavioral
therapy,
pharmacotherapy,
bariatric
surgery
Korean
people
obesity.
Compared
previous
guidelines,
current
five
new
topics
keep
up
constantly
evolving
field
obesity:
diagnosis
women,
mental
illness,
maintenance
after
loss,
use
information
communication
technology-based
interventions
features
has
improved
organization,
more
clearly
linking
PICO
format
references.
We
are
confident
that
these
will
be
a
valuable
resource
all
healthcare
professionals
they
describe
most
well-organized
Pharmacology & Therapeutics,
Journal Year:
2023,
Volume and Issue:
251, P. 108549 - 108549
Published: Oct. 23, 2023
Obesity
and
its
comorbidities,
including
type
2
diabetes
mellitus,
cardiovascular
disease,
heart
failure
non-alcoholic
liver
disease
are
a
major
health
economic
burden
with
steadily
increasing
numbers
worldwide.
The
need
for
effective
pharmacological
treatment
options
is
strong,
but,
until
recently,
only
few
drugs
have
proven
sufficient
efficacy
safety.
This
article
provides
comprehensive
overview
of
obesity
special
focus
on
organ-specific
pathomechanisms.
Bariatric
surgery
as
the
so
far
most-effective
therapeutic
strategy,
current
future
strategies
will
be
discussed.
An
knowledge
about
gut-brain
axis
especially
identification
physiology
incretins
unfolds
high
number
potential
drug
candidates
impressive
weight-reducing
potential.
Future
multi-modal
concepts
in
may
surpass
effectivity
bariatric
not
regard
to
weight
loss,
but
also
associated
comorbidities.
Life,
Journal Year:
2024,
Volume and Issue:
14(7), P. 856 - 856
Published: July 8, 2024
Obesity
is
an
important
condition
affecting
the
quality
of
life
numerous
patients
and
increasing
their
associated
risk
for
multiple
diseases,
including
tumors
immune-mediated
disorders.
Inflammation
appears
to
play
a
major
role
in
development
obesity
represents
central
point
activity
cellular
humoral
components
adipose
tissue.
Macrophages
key
as
main
component
tissue
regulating
chronic
inflammation
modulating
secretion
differentiation
various
pro-
anti-inflammatory
cytokines.
also
involves
series
signaling
pathways
that
might
represent
focus
new
therapies
interventions.
Weight
loss
essential
decreasing
cardiometabolic
risks
degree
inflammation;
however,
latter
can
persist
long
after
excess
weight
lost,
involve
changes
macrophage
phenotypes
ensure
metabolic
adjustment.
A
clear
understanding
pathophysiological
processes
interplay
between
lead
better
comorbidities
may
future
targets
treatment
obesity.
