Assembly of a functional neuronal circuit in embryos of an ancestral metazoan is influenced by environmental signals including the microbiome DOI
Christopher Noack, Sebastian Jenderny, Christoph Giez

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 15, 2024

Abstract Understanding how neural populations evolve to give rise behavior is a major goal in neuroscience. However, the complexity of nervous system most invertebrates and vertebrates complicates deciphering underlying fundamental processes. Here, we explore self-assembly circuits Hydra , an organism with simple but no centralized information processing, improve understanding evolution. The N4 neuronal circuit embryos develops through activity-driven self-assembly, where neurons distinct regions increase connectivity synchronization. Gap junctions vesicle-mediated communication between non-neuronal cells drive rapid assembly, embryo’s prospective oral region exhibiting highest density. An artificial electrical circuit-based model demonstrates dynamic increases synchronization over time, along predictions for selective adaptions connections. Environmental factors, like temperature absent microbiome, modify architecture, suggesting existence certain plasticity development. We propose that these features originated last common bilaterian ancestor, supporting hypothesis basic architecture universal.

Language: Английский

Plant-like heliotropism in a photosymbiotic animal DOI

Eliska Lintnerova,

Callum Shaw,

Matthew Keys

et al.

Journal of Experimental Biology, Journal Year: 2025, Volume and Issue: 228(3)

Published: Feb. 1, 2025

ABSTRACT As in plants, photosynthesis also represents a key energy source photosymbiotic cnidarians bearing microalgae. We observed that the cnidarian sea anemone Anemonia viridis, commonly known as snakelocks anemone, displayed heliotropism or solar tracking their natural habitats. When exposed to sunlight, A. viridis point tentacles towards sun while remaining sessile, facing east at dawn and west dusk they track sun's relative position through day. This phenomenon was previously only plants. Solar movements are driven by peak wavelengths prompt endosymbionts. The heliotropic response absent both bleached (aposymbiotic) symbiotic with chemically inhibited photosynthesis. revealed direct correlation between symbiont oxygen production showed how utilises this mechanism modulate exposure irradiation. Our study exemplifies photosynthetic organisms such plants anemones, display similar behaviour environmental pressures.

Language: Английский

Citations

1
Assembly of a functional neuronal circuit in embryos of an ancestral metazoan is influenced by environmental signals including the microbiome DOI
Christopher Noack, Sebastian Jenderny, Christoph Giez

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 15, 2024

Abstract Understanding how neural populations evolve to give rise behavior is a major goal in neuroscience. However, the complexity of nervous system most invertebrates and vertebrates complicates deciphering underlying fundamental processes. Here, we explore self-assembly circuits Hydra , an organism with simple but no centralized information processing, improve understanding evolution. The N4 neuronal circuit embryos develops through activity-driven self-assembly, where neurons distinct regions increase connectivity synchronization. Gap junctions vesicle-mediated communication between non-neuronal cells drive rapid assembly, embryo’s prospective oral region exhibiting highest density. An artificial electrical circuit-based model demonstrates dynamic increases synchronization over time, along predictions for selective adaptions connections. Environmental factors, like temperature absent microbiome, modify architecture, suggesting existence certain plasticity development. We propose that these features originated last common bilaterian ancestor, supporting hypothesis basic architecture universal.

Language: Английский

Citations

0