New-Onset Graves’ Disease Induced by COVID-19: A Case Report and Literature Review DOI Open Access

Takashi Shinzato,

Tadahiro Yonaha

Cureus, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 6, 2024

We present a case of new-onset Graves' disease in 40-year-old woman following COVID-19 infection. The patient experienced hand tremors, palpitations, shortness breath with minimal exertion, and excessive sweating one week after recovering from COVID-19. Thyroid function tests revealed thyrotoxicosis, elevated free thyroxine, triiodothyronine, suppressed thyroid-stimulating hormone levels. Positive antithyroid peroxidase (TSH) receptor antibodies, along ultrasonography findings diffuse thyroid enlargement hypervascularization, confirmed the diagnosis disease. Scintigraphy was omitted per patient's request. This contributes to growing evidence suggesting SARS-CoV-2 may trigger autoimmune responses leading disorders. discuss epidemiology, clinical characteristics, potential mechanisms COVID-19, reviewing 28 similar cases reported 2020 early 2024. Our analysis reveals varied onset times severity dysfunction post-COVID-19, some progressing storm. highlight importance vigilant post-COVID-19 follow-up contribute understanding SARS-CoV-2's long-term consequences. From cost-benefit perspective, targeted screening approach might be needed for patients persistent symptoms suggestive dysfunction. strategy could facilitate detection treatment, potentially preventing complications reducing healthcare costs.

Language: Английский

New-Onset Graves’ Disease Induced by COVID-19: A Case Report and Literature Review DOI Open Access

Takashi Shinzato,

Tadahiro Yonaha

Cureus, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 6, 2024

We present a case of new-onset Graves' disease in 40-year-old woman following COVID-19 infection. The patient experienced hand tremors, palpitations, shortness breath with minimal exertion, and excessive sweating one week after recovering from COVID-19. Thyroid function tests revealed thyrotoxicosis, elevated free thyroxine, triiodothyronine, suppressed thyroid-stimulating hormone levels. Positive antithyroid peroxidase (TSH) receptor antibodies, along ultrasonography findings diffuse thyroid enlargement hypervascularization, confirmed the diagnosis disease. Scintigraphy was omitted per patient's request. This contributes to growing evidence suggesting SARS-CoV-2 may trigger autoimmune responses leading disorders. discuss epidemiology, clinical characteristics, potential mechanisms COVID-19, reviewing 28 similar cases reported 2020 early 2024. Our analysis reveals varied onset times severity dysfunction post-COVID-19, some progressing storm. highlight importance vigilant post-COVID-19 follow-up contribute understanding SARS-CoV-2's long-term consequences. From cost-benefit perspective, targeted screening approach might be needed for patients persistent symptoms suggestive dysfunction. strategy could facilitate detection treatment, potentially preventing complications reducing healthcare costs.

Language: Английский

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