Journal of the Academy of Nutrition and Dietetics, Journal Year: 2024, Volume and Issue: unknown
Published: July 1, 2024
Language: Английский
Trends in Endocrinology and Metabolism, Journal Year: 2024, Volume and Issue: 35(9), P. 821 - 833
Published: May 8, 2024
Language: Английский
Citations
12
Ageing Research Reviews, Journal Year: 2024, Volume and Issue: 96, P. 102274 - 102274
Published: March 17, 2024
Language: Английский
Citations
11
Frontiers in Public Health, Journal Year: 2024, Volume and Issue: 12
Published: Nov. 7, 2024
Background Although Spain has traditionally followed the Mediterranean diet, in recent years, changes have become noticeable food preferences of population. These include adopting new diets and dietary trends, such as plant-based diets, intermittent fasting raw diets. choices are influenced by cultural, social socio-demographic factors, their impact on health should be studied detail. Aim The objectives this research are: (1) to study prevalence different patterns among Spanish population, (2) explore dependence choice (3) investigate relationship between habits lifestyle population how it affects health. Methods A descriptive cross-sectional was carried out Using a questionnaire constructed validated team, data were collected nutritional, targeted explored. Results valid sample 22,181 people which 17,573 (79.2%) claimed follow pattern, 1,425 (6.4%) 365 (1.6%) vegans, 1,018 (4.6%) practiced fasting, 252 (1.1%) diet 1,548 (7%) other types show that younger (18–25 years old) tend adopt more often than older women type men. On hand, men seem practice frequently. higher tendency found living villages those cities. Moreover, some trends regions Spain, with greater adherence Catalonia, while is common Region Murcia. Finally, results indicate individuals who pay attention experiment various generally health-conscious. This reflected adoption healthier behaviors, exercising reducing intake alcohol sugary drinks.
Language: Английский
Citations
7
International Journal of Biological Sciences, Journal Year: 2024, Volume and Issue: 20(7), P. 2532 - 2554
Published: Jan. 1, 2024
Autophagy plays a critical role in maintaining cellular homeostasis and responding to various stress conditions by the degradation of intracellular components.In this narrative review, we provide comprehensive overview autophagy's molecular basis, biological significance, pharmacological modulation, its relevance lifestyle medicine.We delve into intricate mechanisms that govern autophagy, including macroautophagy, microautophagy chaperone-mediated autophagy.Moreover, highlight significance autophagy aging, immunity, metabolism, apoptosis, tissue differentiation systemic diseases, such as neurodegenerative or cardiovascular diseases cancer.We also discuss latest advancements modulation their potential implications clinical settings.Finally, explore intimate connection between factors emphasizing how nutrition, exercise, sleep patterns environmental can significantly impact autophagic process.The integration medicine research opens new avenues for promoting health longevity through personalized interventions.
Language: Английский
Citations
6
Nutrients, Journal Year: 2024, Volume and Issue: 16(23), P. 4003 - 4003
Published: Nov. 22, 2024
Obesity is one of the world’s major public health challenges. Its pathogenesis and comorbid metabolic disorders share common mechanisms, such as mitochondrial or endoplasmic reticulum dysfunction oxidative stress, gut dysbiosis, chronic inflammation altered autophagy. Numerous pro-autophagy dietary interventions are being investigated for their potential obesity-preventing therapeutic effects. We summarize current data on relationship between autophagy obesity, discuss various regulators autophagy-related genes in prevention ultimate treatment obesity humans, available scientific databases published through July 2024. Lifestyle modifications (such calorie restriction, intermittent fasting, physical exercise), including following a diet rich flavonoids, antioxidants, specific fatty acids, amino acids others, have shown beneficial role induction this process. The activation nutritional tends to elicit consistent response, characterized by certain kinases (including AMPK, IKK, JNK1, TAK1, ULK1, VPS34) suppression others (like mTORC1), deacetylation proteins, alleviation inhibitory interactions BECN1 members Bcl-2 family. Significant health/translational properties many nutrients (nutraceuticals) can affect disease risk mechanisms that include inhibition intervention regulation its comorbidities not yet clear, especially obese individuals.
Language: Английский
Citations
3
Journal of Education Health and Sport, Journal Year: 2025, Volume and Issue: 77, P. 56732 - 56732
Published: Jan. 3, 2025
Introduction: Intermittent fasting (IF) has emerged as a popular dietary intervention for its potential health benefits, including weight management, metabolic improvement, and reduced risk of chronic diseases. The practice alternates periods eating fasting, influencing physiological processes offering an alternative to traditional calorie-restrictive diets. Purpose Work: This paper aims investigate the efficacy IF revolutionary approach maintaining mitigating risks associated with By analyzing contemporary research, seeks elucidate underlying mechanisms broader implications IF. State Knowledge: Existing studies suggest that positively affects markers, enhances insulin sensitivity, promotes autophagy—a cellular repair mechanism crucial longevity disease prevention. Emerging evidence links improved cardiovascular health, inflammation, enhanced cognitive functions. However, variability in outcomes due age, gender, protocols highlights need tailored approaches further research. Material methods: research methodology entailed establishing study aims, undertaking systematic review literature, implementing structured process screen pertinent studies. investigation involved comprehensive search across scientific databases, PubMed Google Scholar. Summary: represents transformative paradigm nutrition science. While preliminary findings are promising, more robust longitudinal required establish standardized validate therapeutic diverse populations. underscores promise strategic tool prevention management
Language: Английский
Citations
0
The journal of nutrition health & aging, Journal Year: 2025, Volume and Issue: 29(4), P. 100480 - 100480
Published: Jan. 10, 2025
Language: Английский
Citations
0
Advances in medical diagnosis, treatment, and care (AMDTC) book series, Journal Year: 2025, Volume and Issue: unknown, P. 203 - 256
Published: Jan. 3, 2025
This chapter explores the intricate relationship between oxidative stress and metabolic diseases, specifically diabetes obesity. It begins with an overview of these conditions, emphasizing their global impact associated dysfunctions. The discussion shifts to biochemical mechanisms stress, focusing on mitochondrial dysfunction ROS production. examines how affects pancreatic beta-cell function insulin resistance, linking hyperglycemia increased damage. Additionally, addresses adipose tissue interplay inflammation in obesity-related complications. concludes by discussing strategies mitigate through pharmacological lifestyle interventions, such as antioxidant therapies, dietary changes, regular exercise, caloric restriction. comprehensive approach aims provide insights into effectively managing thereby improving health addressing challenges posed
Language: Английский
Citations
0
Diabetes Obesity and Metabolism, Journal Year: 2024, Volume and Issue: 26(10), P. 4468 - 4479
Published: Aug. 14, 2024
Abstract Aim To assess the impact of intermittent fasting, with or without probiotic supplementation, versus a calorie‐restricted diet on anthropometric measures, metabolic status and gonadal variables in women polycystic ovary syndrome (PCOS). Methods This is randomized, placebo‐controlled, parallel‐arm clinical trial. The effects 14:10 early time‐restricted eating (eTRE) strategy alone combined probiotics, obese PCOS, were investigated. Participants divided into three groups: eTRE plus probiotics ( n = 30), placebo 30) control group following standard three‐meal‐per‐day daily calorie restriction (DCR) 30). Over 8 weeks, various anthropometric, metabolic, menstrual assessed. Results A total 90 individuals included study, mean body weight 81.4 kg, age 30 years. Mean (standard deviation) loss was not different between groups at week (TRE + probiotic: −2.2 [1.6] kg vs. TRE placebo: −2.9 [2.7] DCR: −2.5 [1.7] kg). revealed that, while all regimes led to reductions weight, mass index, vascular risk indicators, hirsutism acne scores, there no statistically significant differences terms loss, improvements P > .05). Additionally, combining did benefit hormonal cardiometabolic factors Conclusions result significantly greater compared three‐meal DCR diet.
Language: Английский
Citations
3
Cureus, Journal Year: 2023, Volume and Issue: unknown
Published: July 22, 2023
Multiple studies have shown that intermittent fasting (IF) is associated with better health conditions and longer lifespans, as time-restricted feeding (TRF). One crucial explanation IF TRF permit a set length of time for caloric ingestion, during which our systems activate variety mechanisms lead to the enhancement renewal different body systems. Accordingly, benefits are lot greater than those complete calorie restriction (CR). offered underpinnings human revealed when we eat fasting, experience fluctuations in all For relevant medical literature, investigated databases such PubMed/Medline, PubMed Central, Cochrane Library, Google Scholar. The chosen articles were evaluated based on eligibility criteria vetted by quality evaluation methods; 15 finished research papers included study. Of recognized studies, four systematic reviews 11 review articles. publications examined efficacy comparability other restrictive diets. study indicated advantages represent complex interplay involving periodic digestion food, gut flora, circadian clock. further necessary get comprehensive grasp this very molecular blueprint. This could aid producing an effectively planned food treatment can regulate numerous chronic ailments disorders. Furthermore, it might development investigation new pharmacological medicines mimic nutritional therapeutic who unwilling or unable follow kind regimen.
Language: Английский
Citations
7