How Can Spatial Transcriptomic Profiling Advance Our Understanding of Skin Diseases? DOI Creative Commons
Girishkumar Kumaran, Liam Carroll, Nina Muirhead

et al.

Journal of Investigative Dermatology, Journal Year: 2024, Volume and Issue: unknown

Published: Aug. 1, 2024

Spatial transcriptomic (ST) profiling is the mapping of gene expression within cell populations with preservation positional context and represents an exciting new approach to develop our understanding local regional influences upon skin biology in health disease. With ability probe from a few hundred transcripts entire transcriptome, multiple ST approaches are now widely available. In this paper, we review field discuss its application dermatology. Its potential advance disease highlighted through illustrative examples 3 research areas: cutaneous aging, tumorigenesis, psoriasis.

Language: Английский

Posidonia oceanica (L.) Delile Is a Promising Marine Source Able to Alleviate Imiquimod-Induced Psoriatic Skin Inflammation DOI Creative Commons
Laura Micheli, Marzia Vasarri, Donatella Degl’Innocenti

et al.

Marine Drugs, Journal Year: 2024, Volume and Issue: 22(7), P. 300 - 300

Published: June 28, 2024

Psoriasis is a chronic immune-mediated inflammatory cutaneous disease characterized by elevated levels of cytokines and adipokine Lipocalin-2 (LCN-2). Recently, natural plant-based products have been studied as new antipsoriatic compounds. We investigate the ability leaf extract marine plant

Language: Английский

Citations

2
How Can Spatial Transcriptomic Profiling Advance Our Understanding of Skin Diseases? DOI Creative Commons
Girishkumar Kumaran, Liam Carroll, Nina Muirhead

et al.

Journal of Investigative Dermatology, Journal Year: 2024, Volume and Issue: unknown

Published: Aug. 1, 2024

Spatial transcriptomic (ST) profiling is the mapping of gene expression within cell populations with preservation positional context and represents an exciting new approach to develop our understanding local regional influences upon skin biology in health disease. With ability probe from a few hundred transcripts entire transcriptome, multiple ST approaches are now widely available. In this paper, we review field discuss its application dermatology. Its potential advance disease highlighted through illustrative examples 3 research areas: cutaneous aging, tumorigenesis, psoriasis.

Language: Английский

Citations

2