Optics Letters, Journal Year: 2024, Volume and Issue: 50(2), P. 317 - 317
Published: Dec. 9, 2024
Metasurfaces offer a powerful tool to realize label-free and highly sensitive Raman spectroscopy. Embedding metasurfaces into microfluidic channels is promising establish new characterizing platform for microfluids. In this Letter, we present stable method improving the scattering intensity of biological microfluids by using chip embedded with plasmonic metasurface. The metasurface consists nanosphere array coated silver layer, where diameter ∼100 nm. Langmuir–Blodgett chemical spraying were adopted prepare nanosphere-array case red blood cell measurement, giant enhancement spectra achieved compared that without Moreover, two-time obtained under radially polarized beam illumination linearly illumination. Furthermore, device was applied monitor environmental variation rat cells. Peaks in range from 2143 cm −1 2303 arise addition glucose are still obviously distinguishable when additive concentration down 10 −3 M. This indicates high sensitivity mixed cells, which could be further environments such as concentration, pH, sodium salt concentration.
Language: Английский