Efficient, broadly-tunable, hollow-fiber source of megawatt pulses for multiphoton microscopy DOI Creative Commons

Yishai Eisenberg,

Wenchao Wang, Shitong Zhao

et al.

Biomedical Optics Express, Journal Year: 2024, Volume and Issue: 16(2), P. 415 - 415

Published: Dec. 26, 2024

Three-photon fluorescence microscopy (3PM) has driven rapid progress in deep-tissue imaging beyond the depth limit of two-photon microscopy, with impacts neuroscience, immunology, and cancer biology. excitation places a premium on ultrashort pulses high peak power 1300- 1700-nm wavelength bands, which allow deepest imaging. The inefficiency cost current sources these present major barriers to use 3PM biomedical research labs. Fiber such could potentially alleviate problems, but peak-power limitations optical fibers have limited their 3PM. Here, we describe fiber-based source femtosecond multi-megawatt power. Femtosecond at 1030 nm are launched into an antiresonant hollow-core fiber filled argon. By varying only gas pressure, hundreds nanojoules energy sub-100 fs duration obtained wavelengths between 850 1700 nm. This approach is new route efficient low-cost for In particular, 960-nJ 50-fs generated 1300 conversion efficiency 10%. nearly 20-MW order magnitude higher than previous best from solid-core As example capabilities source, used image structure neuronal activity mouse brain as deep 1.1 mm below dura.

Language: Английский

Tutorial on Fourier and Hankel Transforms for Ultrafast Optics DOI Creative Commons
Yihao Chen

Published: Jan. 29, 2025

This tutorial is designed for individuals who are new to the field of ultrafast optics. It was written in response apparent lack comprehensive introductions basic Fourier transform, extending beyond flat-phase description. Additionally, there a need complete derivations several relations involving maintaining its most general formulation. approach avoids arbitrary selection Fourier-transform constants and ensures understanding. shows importance having as parameters. Most important all, have been misuse transform from my observations, which cannot be easily detected by checking smoothness result numerical implementation or seeing if simulation duplicates “overall physics.” problem should solved simple (see Sec. 2.2). I hope that this can help people understand more about especially context In addition, Hankel arises two-dimensional spatial radially-symmetric function, provided. Its based on fast with high accuracy also provided, core element full-field propagation. Feel me send an email any confusion, you think add tutorial. For deeper understanding into pulse propagation involves these transforms, please check out our publicly-shared Github code [https://github.com/AaHaHaa/MMTools].

Language: Английский

Citations

0
Multi-megawatt pulses from 1030 nm to 1300 nm based on soliton self-frequency shifting in nitrogen-filled fiber DOI

Yishai Eisenberg,

Wenchao Wang, Yihao Chen

et al.

Optics Letters, Journal Year: 2025, Volume and Issue: 50(5), P. 1593 - 1593

Published: Jan. 29, 2025

Soliton formation and soliton self-frequency shift are investigated in a hollow-core fiber filled with N 2 gas. With 10-µJ 80-fs input pulses at 1030 nm, solitons greater than 500-nJ energy duration less 100 fs can be generated between 1090 1310 nm. peak powers above 5 MW, we expect that these will useful for applications such as nonlinear microscopy.

Language: Английский

Citations

0
Efficient temporal compression of 10-μJ pulses in periodic layered Kerr media: publisher’s note DOI

Wenchao Wang,

Yishai Eisenberg,

Yihao Chen

et al.

Optics Letters, Journal Year: 2025, Volume and Issue: 50(7), P. 2158 - 2158

Published: March 7, 2025

This publisher's note contains a correction to Opt. Lett.49, 5787 (2024)10.1364/OL.539381.

Language: Английский

Citations

0
Efficient, broadly-tunable, hollow-fiber source of megawatt pulses for multiphoton microscopy DOI Creative Commons

Yishai Eisenberg,

Wenchao Wang, Shitong Zhao

et al.

Biomedical Optics Express, Journal Year: 2024, Volume and Issue: 16(2), P. 415 - 415

Published: Dec. 26, 2024

Three-photon fluorescence microscopy (3PM) has driven rapid progress in deep-tissue imaging beyond the depth limit of two-photon microscopy, with impacts neuroscience, immunology, and cancer biology. excitation places a premium on ultrashort pulses high peak power 1300- 1700-nm wavelength bands, which allow deepest imaging. The inefficiency cost current sources these present major barriers to use 3PM biomedical research labs. Fiber such could potentially alleviate problems, but peak-power limitations optical fibers have limited their 3PM. Here, we describe fiber-based source femtosecond multi-megawatt power. Femtosecond at 1030 nm are launched into an antiresonant hollow-core fiber filled argon. By varying only gas pressure, hundreds nanojoules energy sub-100 fs duration obtained wavelengths between 850 1700 nm. This approach is new route efficient low-cost for In particular, 960-nJ 50-fs generated 1300 conversion efficiency 10%. nearly 20-MW order magnitude higher than previous best from solid-core As example capabilities source, used image structure neuronal activity mouse brain as deep 1.1 mm below dura.

Language: Английский

Citations

0