An electrochemical sensor for dopamine on a graphene-poly(3,4-ethylenedioxythiophene):polystyrene sulphonate hybrid ink nanoplatform

Deleted Journal, Journal Year: 2025, Volume and Issue: 7(4)

Published: April 1, 2025

Abstract Dopamine can be used as a biomarker for diseases such Alzheimer’s, bipolar disorder, schizophrenia, mania, to mention few, well addiction tobacco. Thus, its measurement is of biomedical importance. We present an easy-to-construct, one-step, electrochemical sensor dopamine based on drop coating commercial graphene/poly (3,4-ethylenedioxythiophene):polystyrene sulphonate (Gr-PEDOT:PSS) hybrid ink dispersion bare glassy carbon electrode surface. The conductive polymer’s structural properties and composition were explored using XRD, Raman, FTIR spectroscopy electron microscopy. nanocomposite exhibited uniform size distribution functional groups aromatic, thiol, olefinic bonds improved the surface chemistry between electrolyte/analyte electrode. Characterization through impedance voltammetry demonstrated that Gr-PEDOT:PSS significantly enhances transfer kinetics at therefore improve electrooxidation dopamine. achieved detection limit 0.19 µM within linear concentration range 3.13–400 It also high selectivity against potential interfering agents like ascorbic acid, caffeine, urea, with recovery percentages ranging from 105 109% in human serum samples.

Language: Английский

A cross-cultural examination of bi-directional mentalising in autistic and non-autistic adults

Molecular Autism, Journal Year: 2025, Volume and Issue: 16(1)

Published: May 13, 2025

Language: Английский