Integrated information theory reveals the potential role of the posterior parietal cortex in sustaining conditioning responses in classical conditioning tasks DOI Creative Commons

Tien Cuong Phi,

Shin Ishii, Masashi Kondo

et al.

Frontiers in Neuroscience, Journal Year: 2025, Volume and Issue: 19

Published: Jan. 29, 2025

Classical conditioning is a fundamental associative learning process in which repeated pairings of conditioned stimulus (CS) with an unconditioned (US) lead to the CS eliciting response (CR). Previous research has identified key neural regions involved processing reward-predicting cues and mediating licking behavior. However, mechanisms that sustain high rates across sessions remain elusive, particularly regarding how reward expectation represented on session-by-session basis. While early phases classical have been extensively studied, support consistent performance over time unclear. In this study, we sought understand cortical regions, posterior parietal cortex (PPC), contribute maintaining CR sessions. Using core complex framework derived from Integrated Information Theory (IIT), explored dynamics networks during performance. Our findings suggest while traditional functional connectivity (FC) methods struggled capture complexity sustained behavioral engagement, revealed notably PPC, were significantly correlated enhanced This work suggests potential role PPC supporting expectations responses. By applying investigate substrates behavior, provide novel insights into interaction conditioning, offering promising directions for future

Language: Английский

Unravelling consciousness and brain function through the lens of time, space, and information DOI Creative Commons
Andrea I. Luppi, Fernando Rosas, Pedro A. M. Mediano

et al.

Trends in Neurosciences, Journal Year: 2024, Volume and Issue: 47(7), P. 551 - 568

Published: May 31, 2024

Disentangling how cognitive functions emerge from the interplay of brain dynamics and network architecture is among major challenges that neuroscientists face. Pharmacological pathological perturbations consciousness provide a lens to investigate these complex challenges. Here, we review recent advances about brain's functional organisation have been driven by common denominator: decomposing function into fundamental constituents time, space, information. Whereas unconsciousness increases structure-function coupling across scales, psychedelics may decouple structure. Convergent effects also emerge: anaesthetics, psychedelics, disorders can exhibit similar reconfigurations unimodal-transmodal axis. Decomposition approaches reveal potential translate discoveries species, with computational modelling providing path towards mechanistic integration.

Language: Английский

Citations

4
Is artificial consciousness achievable? Lessons from the human brain DOI Creative Commons
Michele Farisco, Kathinka Evers,

Jean‐Pierre Changeux

et al.

Neural Networks, Journal Year: 2024, Volume and Issue: 180, P. 106714 - 106714

Published: Sept. 7, 2024

Language: Английский

Citations

4
Preliminaries to artificial consciousness: a multidimensional heuristic approach. DOI Creative Commons
Kathinka Evers, Michele Farisco, Raja Chatila

et al.

Physics of Life Reviews, Journal Year: 2025, Volume and Issue: 52, P. 180 - 193

Published: Jan. 5, 2025

The pursuit of artificial consciousness requires conceptual clarity to navigate its theoretical and empirical challenges. This paper introduces a composite, multilevel, multidimensional model as heuristic framework guide research in this field. Consciousness is treated complex phenomenon, with distinct constituents dimensions that can be operationalized for study evaluating their replication. We argue provides balanced approach by avoiding binary thinking (e.g., conscious vs. non-conscious) offering structured basis testable hypotheses. To illustrate utility, we focus on "awareness" case study, demonstrating how specific pragmatically analyzed targeted potential instantiation. By breaking down the intricacies aligning them practical goals, lays groundwork robust strategy advance scientific technical understanding consciousness.

Language: Английский

Citations

0
Human Brain Organoids and the Mereological Fallacy DOI Creative Commons
Matthew Owen, Darren Hight, Anthony G. Hudetz

et al.

Neuroethics, Journal Year: 2025, Volume and Issue: 18(1)

Published: Jan. 6, 2025

Language: Английский

Citations

0
Integrated information theory reveals the potential role of the posterior parietal cortex in sustaining conditioning responses in classical conditioning tasks DOI Creative Commons

Tien Cuong Phi,

Shin Ishii, Masashi Kondo

et al.

Frontiers in Neuroscience, Journal Year: 2025, Volume and Issue: 19

Published: Jan. 29, 2025

Classical conditioning is a fundamental associative learning process in which repeated pairings of conditioned stimulus (CS) with an unconditioned (US) lead to the CS eliciting response (CR). Previous research has identified key neural regions involved processing reward-predicting cues and mediating licking behavior. However, mechanisms that sustain high rates across sessions remain elusive, particularly regarding how reward expectation represented on session-by-session basis. While early phases classical have been extensively studied, support consistent performance over time unclear. In this study, we sought understand cortical regions, posterior parietal cortex (PPC), contribute maintaining CR sessions. Using core complex framework derived from Integrated Information Theory (IIT), explored dynamics networks during performance. Our findings suggest while traditional functional connectivity (FC) methods struggled capture complexity sustained behavioral engagement, revealed notably PPC, were significantly correlated enhanced This work suggests potential role PPC supporting expectations responses. By applying investigate substrates behavior, provide novel insights into interaction conditioning, offering promising directions for future

Language: Английский

Citations

0