A quantitative analysis of the use of anonymization in biomedical research DOI Creative Commons
Thierry Meurers,

Karen Otte,

Hammam Abu Attieh

et al.

npj Digital Medicine, Journal Year: 2025, Volume and Issue: 8(1)

Published: May 14, 2025

Summary Anonymized biomedical data sharing faces several challenges. This systematic review analyzes 1084 PubMed-indexed studies (2018–2022) using anonymized to quantify usage trends across geographic, regulatory, and cultural regions identify effective approaches inform implementation agendas. We identified a significant yearly increase in such with slope of 2.16 articles per 100,000 when normalized against the total number ( p = 0.021). Most used from US, UK, Australia (78.2%). trend remained by country-specific research output. Cross-border was rare (10.5% studies). twelve common sources, primarily US (seven) UK (three), including commercial public entities (five). The prevalence anonymization suggests their practices could guide broader adoption. Rare cross-border differences between countries comparable regulations underscore need for global standards.

Language: Английский

The Current and Future State of AI Interpretation of Medical Images DOI
Pranav Rajpurkar, Matthew P. Lungren

New England Journal of Medicine, Journal Year: 2023, Volume and Issue: 388(21), P. 1981 - 1990

Published: May 24, 2023

The authors examine the advantages and limitations of current clinical radiologic AI systems, new workflows, potential effect generative large multimodal foundation models.

Language: Английский

Citations

227

A guide to sharing open healthcare data under the General Data Protection Regulation DOI Creative Commons
Jip W T M de Kok, Miguel Ángel Armengol de la Hoz,

Y. de Jong

et al.

Scientific Data, Journal Year: 2023, Volume and Issue: 10(1)

Published: June 24, 2023

Sharing healthcare data is increasingly essential for developing data-driven improvements in patient care at the Intensive Care Unit (ICU). However, it also very challenging under strict privacy legislation of European Union (EU). Therefore, we explored four successful open ICU databases to determine how can be shared appropriately EU. A questionnaire was constructed based on Delphi method. Then, follow-up questions were discussed with experts from databases. These encountered similar challenges and regarded ethical legal aspects most challenging. Based approaches databases, expert opinion, literature research, outline distinct openly sharing data, each varying implications regarding security, ease use, sustainability, implementability. Ultimately, formulate seven recommendations guide future initiatives improve advance healthcare.

Language: Английский

Citations

52

An overview and a roadmap for artificial intelligence in hematology and oncology DOI Creative Commons
Wiebke Rösler, Michael Altenbuchinger, Bettina Baeßler

et al.

Journal of Cancer Research and Clinical Oncology, Journal Year: 2023, Volume and Issue: 149(10), P. 7997 - 8006

Published: March 15, 2023

Artificial intelligence (AI) is influencing our society on many levels and has broad implications for the future practice of hematology oncology. However, medical professionals researchers, it often remains unclear what AI can cannot do, are promising areas a sensible application in Finally, limits perils using oncology not obvious to healthcare professionals.

Language: Английский

Citations

49

Examining inclusivity: the use of AI and diverse populations in health and social care: a systematic review DOI Creative Commons

John Marko,

Ciprian Daniel Neagu,

P. B. Anand

et al.

BMC Medical Informatics and Decision Making, Journal Year: 2025, Volume and Issue: 25(1)

Published: Feb. 5, 2025

Abstract Background Artificial intelligence (AI)-based systems are being rapidly integrated into the fields of health and social care. Although such can substantially improve provision care, diverse marginalized populations often incorrectly or insufficiently represented within these systems. This review aims to assess influence AI on care among populations, particularly with regard issues related inclusivity regulatory concerns. Methods We followed Preferred Reporting Items for Systematic Reviews Meta-Analyses guidelines. Six leading databases were searched, 129 articles selected this in line predefined eligibility criteria. Results research revealed disparities outcomes, accessibility, representation groups due biased data sources a lack training datasets, which potentially exacerbate inequalities delivery communities. Conclusion development practices, legal frameworks, policies must be reformulated ensure that is applied an equitable manner. A holistic approach used address disparities, enforce effective regulations, safeguard privacy, promote inclusion equity, emphasize rigorous validation.

Language: Английский

Citations

2

Artificial intelligence in cancer research and precision medicine: Applications, limitations and priorities to drive transformation in the delivery of equitable and unbiased care DOI
Chiara Corti, Marisa Cobanaj, Edward Christopher Dee

et al.

Cancer Treatment Reviews, Journal Year: 2022, Volume and Issue: 112, P. 102498 - 102498

Published: Dec. 11, 2022

Language: Английский

Citations

50

Prediction of Preeclampsia Using Machine Learning and Deep Learning Models: A Review DOI Creative Commons
Sumayh S. Aljameel, Manar Alzahrani,

Reem Almusharraf

et al.

Big Data and Cognitive Computing, Journal Year: 2023, Volume and Issue: 7(1), P. 32 - 32

Published: Feb. 9, 2023

Preeclampsia is one of the illnesses associated with placental dysfunction and pregnancy-induced hypertension, which appears after first 20 weeks pregnancy marked by proteinuria hypertension. It can affect pregnant women limit fetal growth, resulting in low birth weights, a risk factor for neonatal mortality. Approximately 10% pregnancies worldwide are affected hypertensive disorders during pregnancy. In this review, we discuss machine learning deep methods preeclampsia prediction that were published between 2018 2022. Many models have been created using variety data types, including demographic clinical data. We determined techniques successfully predicted preeclampsia. The used most random forest, support vector machine, artificial neural network (ANN). addition, prospects challenges discussed to boost research on intelligence systems, allowing academics practitioners improve their advance automated prediction.

Language: Английский

Citations

25

BRSET: A Brazilian Multilabel Ophthalmological Dataset of Retina Fundus Photos DOI Creative Commons
Luis Filipe Nakayama, David Restrepo, João Matos

et al.

medRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 23, 2024

Abstract Introduction The Brazilian Multilabel Ophthalmological Dataset (BRSET) addresses the scarcity of publicly available ophthalmological datasets in Latin America. BRSET comprises 16,266 color fundus retinal photos from 8,524 patients, aiming to enhance data representativeness, serving as a research and teaching tool. It contains sociodemographic information, enabling investigations into differential model performance across demographic groups. Methods Data three São Paulo outpatient centers yielded medical information electronic records, including nationality, age, sex, clinical history, insulin use, duration diabetes diagnosis. A specialist labeled images for anatomical features (optic disc, blood vessels, macula), quality control (focus, illumination, image field, artifacts), pathologies (e.g., diabetic retinopathy). Diabetic retinopathy was graded using International Clinic Retinopathy Scottish Grading. Validation used Dino V2 Base feature extraction, with 70% training 30% testing subsets. Support Vector Machines (SVM) Logistic Regression (LR) were employed weighted training. Performance metrics included area under receiver operating curve (AUC) Macro F1-score. Results 65.1% Canon CR2 34.9% Nikon NF5050 images. 61.8% patients are female, average age is 57.6 years. affected 15.8% spectrum disease severity. Anatomically, 20.2% showed abnormal optic discs, 4.9% 28.8% macula. Models trained on prediction tasks: “diabetes diagnosis”; “sex classification”; “diabetic diagnosis”. Discussion first multilabel dataset Brazil provides an opportunity investigating biases by evaluating tasks demonstrates value external validation computer vision learners America locally relevant sources. Author Summary In low-resource settings, access open crucial research. Regions such often face underrepresentation, resulting health inequities. To diverse these areas, especially America, we introduce means alleviate AI Comprising integrates empowering researchers investigate groups diseases. extracted centers, includes demographics, features, control, like retinopathy. performed set selected tasks, diagnosis, sex classification, BRSET’s inclusion experiment underscores its potential efficacy classification objectives patient groups, providing insights underrepresented regions.

Language: Английский

Citations

9

Digital Education for the Deployment of Artificial Intelligence in Health Care DOI Creative Commons
Fernando Korn Malerbi, Luis Filipe Nakayama, Robyn Gayle Dychiao

et al.

Journal of Medical Internet Research, Journal Year: 2023, Volume and Issue: 25, P. e43333 - e43333

Published: June 22, 2023

Artificial Intelligence (AI) represents a significant milestone in health care's digital transformation. However, traditional care education and training often lack competencies. To promote safe effective AI implementation, professionals must acquire basic knowledge of machine learning neural networks, critical evaluation data sets, integration within clinical workflows, bias control, human-machine interaction settings. Additionally, they should understand the legal ethical aspects impact adoption. Misconceptions fears about systems could jeopardize its real-life implementation. there are multiple barriers to promoting electronic literacy, including time constraints, overburdened curricula, shortage capacitated professionals. overcome these challenges, partnerships among developers, professional societies, academia essential. Integrating specialists from different backgrounds, specialists, lawyers, social scientists, can significantly contribute combating illiteracy implementation care.

Language: Английский

Citations

22

Current state and prospects of artificial intelligence in allergy DOI Creative Commons
Merlijn van Breugel, Rudolf S.N. Fehrmann,

Marnix Bügel

et al.

Allergy, Journal Year: 2023, Volume and Issue: 78(10), P. 2623 - 2643

Published: Aug. 16, 2023

Abstract The field of medicine is witnessing an exponential growth interest in artificial intelligence (AI), which enables new research questions and the analysis larger types data. Nevertheless, applications that go beyond proof concepts deliver clinical value remain rare, especially allergy. This narrative review provides a fundamental understanding core AI critically discusses its limitations open challenges, such as data availability bias, along with potential directions to surmount them. We provide conceptual framework structure within this discuss forefront case examples. Most these machine learning allergy concern supervised unsupervised clustering, strong emphasis on diagnosis subtyping. A perspective shared guidelines for good practice guide readers applying it effectively safely, prospects advancement initiatives increase impact. anticipate can further deepen our knowledge disease mechanisms contribute precision

Language: Английский

Citations

19

Artificial intelligence in uveitis: A comprehensive review DOI
Luis Filipe Nakayama, Lucas Zago Ribeiro, Robyn Gayle Dychiao

et al.

Survey of Ophthalmology, Journal Year: 2023, Volume and Issue: 68(4), P. 669 - 677

Published: March 4, 2023

Language: Английский

Citations

17