The Role of Hybridization in Species Formation and Persistence

Cold Spring Harbor Perspectives in Biology, Journal Year: 2024, Volume and Issue: 16(12), P. a041445 - a041445

Published: March 4, 2024

Joshua V. Peñalba1, Anna Runemark2, Joana I. Meier3,4, Pooja Singh5,6, Guinevere O.U. Wogan7, Rosa Sánchez-Guillén8, James Mallet9, Sina J. Rometsch10,11, Mitra Menon12, Ole Seehausen5,6, Jonna Kulmuni13,14,16 and Ricardo Pereira15,16 1Museum für Naturkunde, Leibniz Institute for Evolution Biodiversity Science, Center Integrative Discovery, 10115 Berlin, Germany 2Department of Biology, Lund University, 22632 Lund, Sweden 3Tree Life, Wellcome Sanger Institute, Hinxton, Cambridgeshire CB10 1SA, United Kingdom 4Department Zoology, University Cambridge, CB2 3EJ, 5Department Aquatic Ecology, Ecology Evolution, Bern, 3012 Switzerland 6Center & Biogeochemistry, Swiss Federal Science Technology (EAWAG), CH-8600 Kastanienbaum, 7Department Oklahoma State Stillwater, 74078, USA 8Red de Biología Evolutiva, INECOL, Xalapa, Veracruz, CP 91073, Mexico 9Organismal Evolutionary Harvard Massachusetts 02138, 10Department Yale New Haven, Connecticut 06511, 11Yale Biospheric Studies, 12Department California Davis, 95616, 13Department Population Ecosystem Dynamics, Amsterdam, 1098 XH The Netherlands 14Organismal Biology Research Programme, Helsinki, Biocenter 3, Finland 15Department Museum Natural History Stuttgart, Stuttgart 70191, Correspondence: ricardojn.pereira{at}gmail.com ↵16 These authors contributed equally to this work.

Language: Английский

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The Ecology of Hybrid Incompatibilities

Cold Spring Harbor Perspectives in Biology, Journal Year: 2023, Volume and Issue: 16(9), P. a041440 - a041440

Published: Dec. 27, 2023

Ecologically mediated selection against hybrids, caused by hybrid phenotypes fitting poorly into available niches, is typically viewed as distinct from epistatic Dobzhansky-Muller incompatibilities. Here, we show how transgressive in hybrids manifests incompatibility. After outlining our logic, summarize current approaches for studying ecology-based on hybrids. We then quantitatively review QTL-mapping studies and find traits differing between parent taxa are polygenic. Next, describe verbal models of translate to phenotypic genetic fitness landscapes, highlighting emerging detecting polygenic Finally, a synthesis published data, report that trait transgression-and thus possibly extrinsic incompatibility hybrids-escalates with the divergence parents. discuss conceptual implications conclude ecological basis will facilitate new discoveries about mechanisms speciation.

Language: Английский

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Fisher's Geometric Model as a Tool to Study Speciation

Cold Spring Harbor Perspectives in Biology, Journal Year: 2024, Volume and Issue: 16(7), P. a041442 - a041442

Published: Jan. 22, 2024

Hilde Schneemann1, Bianca De Sanctis1,2 and John J. Welch1 1Department of Genetics, University Cambridge, Cambridge CB2 3EH, United Kingdom 2Department Zoology, 3EJ, Correspondence: hilde.schneemann{at}evobio.eu

Language: Английский

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Archaic introgression and the distribution of shared variation under stabilizing selection

PLoS Genetics, Journal Year: 2025, Volume and Issue: 21(3), P. e1011623 - e1011623

Published: March 31, 2025

Many phenotypic traits are under stabilizing selection, which maintains a population’s mean value near some optimum. The dynamics of and trait architectures selection have been extensively studied for single populations at steady state. However, natural seldom state often structured in way. Admixture introgression events may be common, including over human evolutionary history. Because results against the minor allele trait-affecting locus, alleles from parental ancestry will selected after admixture. We show that site-frequency spectrum can used to model genetic architecture such traits, allowing study complex multi-population settings. use simple deterministic two-locus predict reduction introgressed around trait-contributing loci. From this individual-based simulations, we introgressed-ancestry is depleted When between two diverged occurs both directions, as has inferred humans Neanderthals, locations regions with tend shared across populations. argue optima explain recent observations human-introgressed Neanderthal genome overlap Neanderthal-ancestry deserts humans.

Language: Английский

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Repetitive DNAs: The “invisible” regulators of insect adaptation and speciation

Current Opinion in Insect Science, Journal Year: 2024, Volume and Issue: 67, P. 101295 - 101295

Published: Nov. 7, 2024

Language: Английский

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Evolution of Hybrid Inviability Associated With Chromosome Fusions

Molecular Ecology, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 3, 2025

ABSTRACT Chromosomal rearrangements, such as inversions, have received considerable attention in the speciation literature due to their hampering effects on recombination. Less is known about how other chromosome fissions and fusions, can affect evolution of reproductive isolation. Here, we use crosses between populations wood white butterfly ( Leptidea sinapis ) with different karyotypes identify genomic regions associated hybrid inviability. We map inviability candidate loci by contrasting allele frequencies F 2 hybrids that survived until adult stage individuals same cohort succumbed incompatibilities. Hybrid high genetic differentiation parental populations, reduced recombination rates, are enriched near fusions. By analysing sequencing coverage, exclude aneuploidies a direct link Instead, our results point an indirect relationship possibly related fused chromosomes. Thus, postzygotic isolation chromosomal providing crucial empirical evidence for idea number differences taxa contribute speciation.

Language: Английский

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Genomic incompatibilities are persistent barriers when speciation happens with gene flow in Formica ants

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2025, Volume and Issue: unknown

Published: April 1, 2025

Abstract A current goal of speciation research is to identify the loci underlying reproductive barriers between species. Locating such barrier in empirical data difficult due often complex demographic history diverged taxa and heterogeneity evolutionary forces across genome. Here we take advantage a natural case hybridization two wood ant species ( Formica aquilonia F. polyctena ) regions reduced long-term gene flow using demographically explicit scans non-admixed genomes. In addition candidate Bateson-Dobzhansky-Muller incompatibilities (BDMIs) through an imbalanced recombinant haplotype frequency analysis × hybrid Both approaches find that are scattered Furthermore, BDMIs significantly overlap with identified by gIMble, indicating have persisted despite divergence Intriguingly, interact network number pairwise interactions BDMI has correlates its strength: hub-like many reduce more effectively. Finally regards function, gIMble arise outside both coding sequences (CDS) transposable elements. contrast, where co-locate associated introns, implying potential role alternative splicing or regulation incompatibilities, rather than CDS divergence. Overall, our results highlight underappreciated impact multilocus need consider connectivity future work. Significance Detecting closely related common research. However, reliable detection confounding signals genomic data. different, recently developed genome, on-going flow, maintain distinct We reveal incompatible can act as persistent barriers, theoretical predictions for their collapse under flow. Connectivity also seems play important persistence. These

Language: Английский

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Rapid and predictable genome evolution across three hybrid ant populations

PLoS Biology, Journal Year: 2022, Volume and Issue: 20(12), P. e3001914 - e3001914

Published: Dec. 20, 2022

Hybridization is frequent in the wild but it unclear when admixture events lead to predictable outcomes and if so, at what timescale. We show that selection led correlated sorting of genetic variation rapidly after 3 hybrid Formica aquilonia × F. polyctena ant populations. Removal ancestry from species with lowest effective population size happened all populations, consistent purging deleterious load. This process was modulated by recombination rate density functional sites. Moreover, haplotypes signatures positive either were more likely fix hybrids. These mechanisms mosaic genomes comparable proportions. Our work demonstrates evolution over short timescales nature.

Language: Английский

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Archaic introgression and the distribution of shared variation under stabilizing selection

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: Aug. 20, 2024

Abstract Many phenotypic traits are under stabilizing selection, which maintains a population’s mean value near some optimum. The dynamics of and trait architectures selection have been extensively studied for single populations at steady state. However, natural seldom state often structured in way. Admixture introgression events may be common, including over human evolutionary history. Because results against the minor allele trait-affecting locus, alleles from parental ancestry will selected after admixture. We show that site-frequency spectrum can used to model genetic architecture such traits, allowing study complex multi-population settings. use simple deterministic two-locus predict reduction introgressed around trait-contributing loci. From this individual-based simulations, we introgressed-ancestry deserts enriched When between two diverged occurs both directions, as has inferred humans Neanderthals, locations tend shared across populations. argue optima explain recent observations regions depleted human-introgressed Neanderthal genome overlap with Neanderthal-ancestry humans.

Language: Английский

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The role of gene presence–absence variations on genetic incompatibility in Asian rice

New Phytologist, Journal Year: 2023, Volume and Issue: 239(2), P. 778 - 791

Published: May 17, 2023

Summary Genetic incompatibilities are widespread between species. However, it remains unclear whether they all originated after population divergence as suggested by the Bateson–Dobzhansky–Muller model, and if not, what is their prevalence distribution within populations. The gene presence–absence variations (PAVs) provide an opportunity for investigating gene–gene incompatibility. Here, we searched repulsion of coexistence PAVs to identify negative interaction functions separately in two Oryza sativa subspecies. Many involved subspecies‐specific epistasis segregate at low‐to‐intermediate frequencies focal subspecies but low or high other Incompatible enriched functional groups, defense response protein phosphorylation, which associated with plant immunity consistent autoimmunity being a known mechanism hybrid incompatibility plants. Genes groups older seldom directly interact each other. Instead, younger diverse functions. Our results illustrate landscape genetic rice, where many incompatible pairs have already segregated polymorphisms subspecies, novel interactions defense‐related genes

Language: Английский

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