Spatiotemporal Trends in the Prevalence of Obstructive Sleep Apnoea Across China: A Multilevel Meta-Analysis Incorporating Geographic and Demographic Stratification (2000-2024)

Nature and Science of Sleep, Journal Year: 2025, Volume and Issue: Volume 17, P. 879 - 903

Published: May 1, 2025

Language: Английский

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Obesity and survival in advanced non-small cell lung cancer patients treated with chemotherapy, immunotherapy, or chemoimmunotherapy: a multicenter cohort study

BMC Medicine, Journal Year: 2024, Volume and Issue: 22(1)

Published: Oct. 14, 2024

The association of body mass index (BMI) with survival outcomes in patients advanced non-small cell lung cancer (NSCLC) treated first-line chemotherapy, immunotherapy, or chemoimmunotherapy is controversial. We aimed to investigate these associations, including associations male and female specifically, a multicenter cohort study.

Language: Английский

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Weight trends amongst adults with diabetes or hypertension during the COVID-19 pandemic: an observational study using OpenSAFELY

British Journal of General Practice, Journal Year: 2024, Volume and Issue: 74(748), P. e767 - e776

Published: Jan. 31, 2024

Background COVID-19 pandemic restrictions may have influenced behaviours related to weight. Aim To describe patterns of weight change among adults living in England with type 2 diabetes (T2D) and/or hypertension during the pandemic. Design and setting An observational cohort study using routinely collected health data approximately 40% England, accessed through OpenSAFELY service inside TPP. Method Clinical sociodemographic characteristics associated rapid gain (>0.5 kg/m /year) were investigated multivariable logistic regression. Results Data extracted on T2D ( n = 1 231 455, 43.9% female, 76.0% White British) or 3 558 405, 49.7% 84.3% British). Adults lost overall (median δ −0.1 /year [interquartile range {IQR} −0.7–0.4]). However, was common (20.7%) following: sex (male versus female: adjusted odds ratio [aOR] 0.78 [95% confidence interval {CI} 0.77 0.79]); age (older reduced odds, for example, aged 60–69 years 18–29 years: aOR 0.66 CI 0.61 0.71]); deprivation (least deprived Index Multiple Deprivation [IMD] quintile most IMD quintile: 0.87 0.85 0.89]); ethnicity (Black White: 0.95 0.92 0.98]); mental conditions (for depression: 1.13 1.12 1.15]); treatment (non-insulin no pharmacological treatment: 0.68 0.67 0.69]). maintained stable 0.0 [IQR −0.6–0.5]); however, (24.7%) similar as T2D. Conclusion Among hypertension, more females, younger adults, those areas, conditions.

Language: Английский

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Obesity-Related Complications Including Dysglycemia Based on 1-h Post-Load Plasma Glucose in Children and Adolescents Screened before and after COVID-19 Pandemic

Nutrients, Journal Year: 2024, Volume and Issue: 16(15), P. 2568 - 2568

Published: Aug. 5, 2024

Childhood obesity, with its metabolic complications, is a problem of public health. The International Diabetes Federation (IDF) has recommended glucose levels 1 h post oral load (1h-PG) > 155–209 mg/dL as diagnostic for intermediate hyperglycemia (IH), while >209 type 2 diabetes (T2D). aim the study was to assess occurrence prediabetes, IH, and T2D in children adolescents simple obesity according criteria American Association (ADA) IDF, effect COVID-19 pandemic on these disorders. Analysis included 263 screened either prepandemic (PRE—113 cases) or post-pandemic period (POST—150 cases). All underwent OGTT measurements insulin every 0.5 h, lipid profile, other tests; indices if resistance (IR): HOMA, QUICKI, Matsuda index, AUC (glu/ins) were calculated. incidence T2D, IH higher POST respect PRE, significant differences IR, except HOMA. Significant observed assessed parameters metabolism among groups normal tolerance (NGT), some similarities between (based 1h-PG) prediabetes. Increased frequency dysglycemia after pandemic. Metabolic profile patients at 1h-PG “intermediate” NGT

Language: Английский

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