Frontiers in Pharmacology,
Journal Year:
2023,
Volume and Issue:
14
Published: Oct. 17, 2023
Background:
Polypharmacy,
defined
as
the
simultaneous
use
of
multiple
medications
by
a
patient,
is
worldwide
problem
rising
prevalence.
Paving
way
for
drug
interactions,
adverse
reactions
and
non-adherence,
it
leads
to
negative
health
outcomes,
increased
healthcare
services
costs.
Since
closely
related
multimorbidity,
peaks
in
older
adults.
So
far,
not
many
polypharmacy
management
programs
elderly
have
been
introduced
practice.
However,
due
rapid
ageing
European
societies,
there
an
urgent
need
implement
them
more
widely.
Objective:
The
aim
this
study
was
benchmark
available
Europe
creating
dedicated
benchmarking
application.
Methods:
It
cross-sectional
based
on
online
survey
targeting
professionals
other
stakeholders
across
countries.
Data
collected
were
reused
design
Results:
As
911
respondents
from
all
but
two
EU
countries
took
part
study.
Out
participants,
496
(54.4%)
reported
availability
various
activities
or
formal
that
known
them.
These
had
goals,
which
improved
patient
safety
indicated
most
common
objective
(65.1%
cases).
typical
settings
such
primary
care
(49.4%),
with
pharmacists
doctors
being
often
those
providing
(61.7%
35.5%
cases,
respectively).
Vast
majority
applied
diverse
forms
reviews.
identified
assessed
against
four
predefined
dimensions
effectiveness,
applicability,
scalability
cost-effectiveness.
lowest
scores
obtained
within
last
these
categories,
unavailability
relevant
data.
Based
results,
application
constructed.
allows
comparing
individual
program
ones,
particularly,
national
context.
Conclusion:
By
strong
evidence,
findings
study,
coupled
application,
can
prove
valuable
aiding
clinicians
policymakers
implementation
expansion
elderly.
OECD health working papers,
Journal Year:
2022,
Volume and Issue:
unknown
Published: Sept. 13, 2022
Poor
medication
practices
and
inadequate
system
infrastructure—resulting
in
poor
adherence,
medication-related
harms,
errors—too
often
results
patient
harm.
As
many
as
1
10
hospitalizations
OECD
countries
may
be
caused
by
a
event
one
five
inpatients
experience
harms
during
hospitalization.
Together,
costs
from
avoidable
admissions
due
to
events
added
length
of
stay
preventable
hospital-acquired
total
over
USD
54
billion
countries.
This
report
includes
four
components;
it
1)
assess
the
human
impact
economic
safety
countries,
2)
explores
opportunities
improve
prescribing
3)
examines
state-of-the
art
systems
policies
for
improving
safety,
4)
provides
recommendations
at
national
level.
Frontiers in Pharmacology,
Journal Year:
2021,
Volume and Issue:
12
Published: Nov. 26, 2021
Polypharmacy
paves
the
way
for
non-adherence,
adverse
drug
reactions,
negative
health
outcomes,
increased
use
of
healthcare
services
and
rising
costs.
Since
it
is
most
prevalent
in
older
adults,
there
an
urgent
need
introducing
effective
strategies
to
prevent
manage
problem
this
age
group.
Frontiers in Pharmacology,
Journal Year:
2023,
Volume and Issue:
14
Published: Aug. 2, 2023
Clinical
pharmacy
as
an
area
of
practice,
education
and
research
started
developing
around
the
1960s
when
pharmacists
across
globe
gradually
identified
need
to
focus
more
on
ensuring
appropriate
use
medicines
improve
patient
outcomes
rather
than
being
engaged
in
manufacturing
supply.
Since
that
time
numerous
studies
have
shown
positive
impact
clinical
services
(CPS).
The
for
wider
adoption
CPS
worldwide
becomes
urgent,
global
population
ages,
prevalence
polypharmacy
well
shortage
healthcare
professionals
is
rising.
At
same
time,
there
great
pressure
provide
both
high-quality
cost-effective
health
services.
All
these
challenges
urgently
require
a
new
paradigm
system
architecture.
One
most
answers
increase
utilization
potential
highly
educated
skilled
widely
available
countries,
i.e.,
pharmacists,
who
are
positioned
prevent
manage
drug-related
problems
together
with
safe
effective
medications
further
care
relating
medication
adherence.
Unfortunately,
still
underdeveloped
underutilized
some
parts
Europe,
namely,
Central
Eastern
European
(CEE)
countries.
This
paper
reviews
current
situation
development
CEE
countries
prospects
future
region.
The Annual Review of Pharmacology and Toxicology,
Journal Year:
2019,
Volume and Issue:
60(1), P. 661 - 681
Published: Oct. 7, 2019
Polypharmacy
describes
the
concomitant
use
of
multiple
medicines
and
represents
a
growing
global
challenge
attributable
to
aging
populations
with
an
increasing
prevalence
multimorbidity.
can
be
appropriate
but
is
problematic
when
increased
risk
harm
from
interactions
between
drugs
or
diseases
burden
administering
monitoring
outweighs
plausible
benefits.
has
substantial
economic
impact
in
service
demand
hospitalization
as
well
detrimental
on
patients'
quality
life.
Apart
causing
avoidable
harm,
polypharmacy
also
lead
therapeutic
failure,
up
50%
patients
who
take
four
more
medications
not
taking
them
prescribed.
Guidance
needed
support
clinicians
defining
achieving
realistic
goals
drug
treatment,
system
change
necessary
aid
implementation.
This
article
outlines
lessons
two
programs
that
aim
address
these
challenges:
Scottish
guidance
prescribing
European
Union
SIMPATHY
project.
Paramedicine,
Journal Year:
2023,
Volume and Issue:
20(1), P. 4 - 22
Published: Jan. 1, 2023
Community
paramedicine
is
a
globally
evolving
model
of
care
where
paramedics
provide
community-based,
preventative
and
primary
healthcare
services.
With
increased
global
interest
adaptation
the
community
model,
there
lack
clear
definition
role
paramedic.
This
study
sought
to
come
an
international
consensus
on
A
four-phase
Delphi
methodology
was
utilised
achieve
systematic
approach
expert
identification
performed
reported
in
line
with
Conducting
REporting
DElphi
Studies
standard.
total
94
experts
were
identified
76
consented
involvement
this
Delphi.
Response
rate
ranged
from
81.6%
(Phase
1)
63.1%
2).
Participants
expressed
importance
paramedic
having
components
attributed
health
care,
promotion,
chronic
disease
management
advanced
clinical
assessment.
that
these
are
essential
skill
set,
which
distinguishes
other
frontline
paramedics.
final
91%
agreement
achieved.
The
achieved
as
follows:
provides
person-centred
diverse
range
settings
address
needs
community.
Their
practice
may
include
provision
management,
assessment
needs-based
interventions.
They
should
be
integrated
interdisciplinary
teams
aim
improve
patient
outcomes
through
education,
advocacy
system
navigation.
adoption
will
enhance
efforts
promote
value
specialist
role,
enabling
better
understanding
how
contributes
wider
system.
[Media:
see
text]
PLoS ONE,
Journal Year:
2018,
Volume and Issue:
13(4), P. e0195232 - e0195232
Published: April 18, 2018
Background
Multimorbidity
and
its
associated
polypharmacy
contribute
to
an
increase
in
adverse
drug
events,
hospitalizations,
healthcare
spending.
This
study
aimed
address:
what
exists
regarding
management
the
European
Union
(EU);
why
programs
were,
or
were
not,
developed;
and,
how
identified
initiatives
developed,
implemented,
sustained.
Methods
Change
principles
(Kotter)
normalization
process
theory
(NPT)
informed
data
collection
analysis.
Nine
case
studies
conducted
eight
EU
countries:
Germany
(Lower
Saxony),
Greece,
Italy
(Campania),
Poland,
Portugal,
Spain
(Catalonia),
Sweden
(Uppsala),
United
Kingdom
(Northern
Ireland
Scotland).
The
workflow
included
a
review
of
country/region
specific
policies,
key
informant
interviews
with
stakeholders
involved
policy
development
implementation
focus
groups
clinicians
managers.
Data
analyzed
using
thematic
analysis
individual
cases
framework
across
cases.
Results
Polypharmacy
five
regions
(Catalonia,
Lower
Saxony,
Northern
Ireland,
Scotland,
Uppsala)
all
care
settings.
There
was
agreement,
even
without
initiatives,
that
is
significant
issue
address.
Common
themes
were:
locally
adapted
solutions,
organizational
culture
supporting
innovation
teamwork,
adequate
workforce
training,
multidisciplinary
teams,
changes
workflow,
redefinition
roles
responsibilities
professionals,
policies
legislation
initiative,
information
communication
systems
assist
implementation.
Depending
on
setting,
these
considered
either
facilitators
barriers
Conclusion
Within
studied
countries,
not
widely
addressed.
These
results
highlight
importance
change
theory-based
strategies,
provide
examples
can
managers
policymakers
developing
new
scaling
up
existing
ones,
particularly
places
currently
lacking
such
initiatives.
International Journal of Clinical Practice,
Journal Year:
2020,
Volume and Issue:
75(8)
Published: Nov. 29, 2020
Opioid
misuse
and
overuse
have
contributed
to
a
widespread
overdose
crisis
many
patients
physicians
are
considering
medical
cannabis
support
opioid
tapering
chronic
pain
control.
Using
five-step
modified
Delphi
process,
we
aimed
develop
consensus-based
recommendations
on:
1)
when
how
safely
initiate
titrate
cannabinoids
in
the
presence
of
opioids,
2)
taper
opioids
3)
monitor
evaluate
outcomes
treating
with
cannabinoids.
ESC Heart Failure,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Feb. 4, 2025
The
Heart
Failure
Frailty
Score
(HFFS)
is
a
novel,
multidimensional
tool
to
assess
frailty
in
patients
with
heart
failure
(HF).
It
has
been
developed
overcome
limitations
of
existing
assessment
tools
while
being
practical
for
clinical
use.
HFFS
reflects
the
concept
as
multidimensional,
dynamic
and
potentially
reversible
state,
which
increases
vulnerability
stressors
risk
poor
outcomes
HF.
was
through
Delphi
consensus
process
involving
54
international
experts.
This
approach
involved
iterative
rounds
questionnaires
interviews,
where
panel
experts
provided
their
opinions
on
specific
questions
prepared
by
Steering
Committee.
were
invited
vote
share
views
anonymously,
using
5-point
Likert
scale
over
rounds.
An
80%
threshold
set
agreement
or
disagreement
each
statement.
Twenty-two
variables
from
four
domains
(clinical,
functional,
psycho-cognitive
social)
have
selected
inclusion
after
third
round
process.
A
shorter
version
(S-HFFS),
including
10
variables,
also
daily
new
identification
should
enables
healthcare
providers
identify
potential
'red
flags'
order
develop
personalized
care
plans.
next
step
will
be
validate
score
Korean Medical Education Review,
Journal Year:
2025,
Volume and Issue:
27(1), P. 60 - 81
Published: Feb. 28, 2025
The
development
and
implementation
of
a
systematic
program
evaluation
framework
is
critical
for
improving
the
quality
undergraduate
medical
education.
At
Yonsei
University
College
Medicine,
we
established
following
five
domains
that
encompass
various
aspects
educational
experiences:
(1)
preclinical
curriculum;
(2)
clinical
(3)
environment,
resources,
systems;
(4)
performance
students
graduates
outcomes;
(5)
outcomes
curriculum.
Specific
indicators
were
designed
within
these
validated
through
Delphi
technique,
which
integrated
expert
opinions.
In
total,
98
identified
across
domains.
These
will
function
as
comprehensive
tool
assessing
education
programs.
proposed
addresses
both
shortand
long-term
changes,
facilitating
monitoring,
continuous
improvement
curricula,
better
students.
As
this
grounded
in
unique
context
institution,
it
appropriate
interactions
at
stages.
Furthermore,
may
serve
strategic
foundation
identifying
areas
require
improvement,
ensuring
curriculum
aligns
with
current
standards
practices.
framework’s
structured
approach
continuing
processes
make
possible
to
obtain
essential
data
ongoing
development,
potentially
contributing
robust
system
findings
study
are
expected
valuable
reference
developing
similar
frameworks
other
schools.
Journal of Medical Internet Research,
Journal Year:
2022,
Volume and Issue:
24(9), P. e37337 - e37337
Published: Sept. 8, 2022
Background
Health-related
misinformation
can
be
propagated
via
social
media
and
is
a
threat
to
public
health.
Several
quality
assessment
tools
principles
evaluate
health-related
information
in
the
domain
exist;
however,
these
were
not
designed
specifically
for
media.
Objective
This
study
aims
develop
Principles
Information
on
Social
Media
(PRHISM),
which
used
of
content.
Methods
A
modified
Delphi
approach
was
obtain
expert
consensus
functions
PRHISM.
Health
experts
recruited
Twitter,
email,
snowballing.
total
3
surveys
administered
between
February
2021
May
2021.
The
first
survey
informed
by
literature
review
included
open-ended
questions
items
from
existing
tools.
Subsequent
results
proceeding
survey.
Consensus
deemed
if
≥80%
agreement
reached,
with
considered
relevant
include
After
third
survey,
finalized,
an
instruction
manual
scoring
tool
PRHISM
developed
circulated
participants
final
feedback.
Results
34
consented
participate,
whom
18
(53%)
responded
all
surveys.
In
total,
13
When
instructions
circulated,
no
objections
wording
received.
Conclusions
tool,
along
system
implementation
tool.
promote
accessibility,
transparency,
provision
authoritative
evidence-based
support
consumers’
relationships
health
care
providers.
provided
These
may
also
useful
content
creators
developing
high-quality
assist
consumers
discerning
high-
low-quality
information.