International Journal of Nanomedicine, Journal Year: 2025, Volume and Issue: Volume 20, P. 3445 - 3470

Published: March 1, 2025

Advances in nanotechnology have opened new avenues for precision therapy, personalized medicine, and multifunctional theranostics atherosclerosis (AS). This review provides a comprehensive overview of the role nanoparticles (NPs) medicine AS, discussing their applications, challenges, future prospects. The first analyzes current treatment landscape AS outlines potential biological targets therapy. Various nanocarriers, including organic, inorganic, hybrid systems, are evaluated therapeutic potential, with focus on targeted drug delivery, anti-inflammatory vascular repair, plaque stabilization, lipid clearance. Additionally, explores NP preparation methods, emphasizing strategies to enhance loading, stability, controlled release. Finally, translational challenges NP-based therapies, biocompatibility, large-scale production, regulatory hurdles, clinical implementation, critically analyzed. Future directions highlight importance interdisciplinary collaboration technological innovation advancing nanoparticle-based AS.

Language: Английский