Gut microbiota — bidirectional modulator: role in inflammatory bowel disease and colorectal cancer DOI Creative Commons
Xueling Cui, Changfeng Li, Jing Zhong

et al.

Frontiers in Immunology, Journal Year: 2025, Volume and Issue: 16

Published: April 30, 2025

The gut microbiota is a diverse ecosystem that significantly impacts human health and disease. This article focuses on how the interacts with inflammatory bowel diseases colorectal tumors, especially through immune regulation. plays role in system development regulation, while body's status can also affect composition of microbiota. These microorganisms exert pathogenic effects or correct disease states gastrointestinal actions toxins secretions, inhibition responses, DNA damage, regulation gene expression, protein synthesis. its metabolites are essential progression tumors. complexity bidirectionality this connection tumors inflammation might render it new therapeutic target. Hence, we explore strategies for microbiota, highlighting potential probiotics fecal transplantation to restore adjust microbial community. Additionally, address challenges future research directions area concerning

Language: Английский

Gut microbiota — bidirectional modulator: role in inflammatory bowel disease and colorectal cancer DOI Creative Commons
Xueling Cui, Changfeng Li, Jing Zhong

et al.

Frontiers in Immunology, Journal Year: 2025, Volume and Issue: 16

Published: April 30, 2025

The gut microbiota is a diverse ecosystem that significantly impacts human health and disease. This article focuses on how the interacts with inflammatory bowel diseases colorectal tumors, especially through immune regulation. plays role in system development regulation, while body's status can also affect composition of microbiota. These microorganisms exert pathogenic effects or correct disease states gastrointestinal actions toxins secretions, inhibition responses, DNA damage, regulation gene expression, protein synthesis. its metabolites are essential progression tumors. complexity bidirectionality this connection tumors inflammation might render it new therapeutic target. Hence, we explore strategies for microbiota, highlighting potential probiotics fecal transplantation to restore adjust microbial community. Additionally, address challenges future research directions area concerning

Language: Английский

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