Metabolites,
Journal Year:
2022,
Volume and Issue:
12(3), P. 205 - 205
Published: Feb. 24, 2022
Metabolomics
in
human
serum
samples
provide
a
snapshot
of
the
current
metabolic
state
an
individuum.
Metabolite
concentrations
are
influenced
by
both
genetic
and
environmental
factors.
Concentrations
certain
metabolites
can
further
depend
on
age,
sex,
menopause,
diet
study
participants.
A
better
understanding
these
relationships
is
pivotal
for
planning
metabolomics
studies
involving
subjects
interpretation
their
results.
We
generated
one
largest
single-site
targeted
data
sets
consisting
175
quantified
6872
identified
significantly
associated
with
body
mass
index,
diet,
menopausal
status.
While
most
our
results
agree
previous
large-scale
studies,
we
also
found
novel
associations
including
serotonin
as
sex
BMI-related
metabolite
sarcosine
C2
carnitine
showing
higher
post-menopausal
women.
Finally,
observed
strong
between
consumption
food
items
metabolites,
mostly
phosphatidylcholines
lysophosphatidylcholines.
Most,
strongest,
were
habitual
meat
intake
while
no
significant
fruits,
vegetables,
grain
products.
Summarizing,
reconfirm
findings
from
population-based
independent
cohort.
Together,
will
ultimately
enable
consolidation
which
related
to
BMI,
menopause
well
participants'
diet.
Aquaculture Reports,
Journal Year:
2020,
Volume and Issue:
18, P. 100496 - 100496
Published: Oct. 8, 2020
Recently,
the
concept
of
precision
nutrition
has
emerged
in
aquaculture,
and
there
is
increasing
discussion
on
this
topic.
Some
researchers
have
defined
as
feeding,
which
means
that
nutrient
contents
feed
should
meet
requirements
for
an
animal's
optimal
production
performance
achieve
minimum
fodder
waste
at
same
time.
In
practice,
include
a
comprehensive
survey
genetic
background,
living
habits,
metabolic
characteristics,
water
ecological
environment
other
factors.
Precision
nutritional
regulation
covers
every
level,
from
genes,
cells,
tissues
to
whole
organism.
Through
interacting
with
nutrients
activate
or
inhibit
signalling
pathways/networks
within
regulate
gene
expression
protein
synthesis
subsequently
affect
composition,
content
deposition
sites
carbohydrates,
lipids,
proteins
trace
elements.
Therefore,
we
propose
intervention
needs
be
carried
out
perspectives
'precision
feeding',
metabolism',
output'
support'
simultaneously.
This
review
intends
elaborate
evolution,
theoretical
system,
composition
technical
together
aspects
regulation.
knowledge
will
provide
reference
sustainable
development
aquaculture
industry
harvesting
quality
products.
Foods,
Journal Year:
2021,
Volume and Issue:
10(6), P. 1249 - 1249
Published: May 31, 2021
A
healthy
condition
is
defined
by
complex
human
metabolic
pathways
that
only
function
properly
when
fully
satisfied
nutritional
inputs.
Poor
intakes
are
associated
with
a
number
of
diseases,
such
as
diabetes,
obesity,
atherosclerosis,
hypertension,
and
osteoporosis.
In
recent
years,
nutrition
science
has
undergone
an
extraordinary
transformation
driven
the
development
innovative
software
analytical
platforms.
However,
complexity
variety
chemical
components
present
in
different
food
types,
diversity
interactions
biochemical
networks
biological
systems,
makes
research
complicated
field.
Metabolomics
"-omic",
joining
proteomics,
transcriptomics,
genomics
affording
global
understanding
systems.
this
review,
we
main
metabolomics
approaches,
highlight
applications
potential
for
approaches
advancing
research.
Metabolites,
Journal Year:
2021,
Volume and Issue:
12(1), P. 15 - 15
Published: Dec. 24, 2021
Metabolomics
uses
advanced
analytical
chemistry
methods
to
analyze
metabolites
in
biological
samples.
The
most
intensively
studied
samples
are
blood
and
its
liquid
components:
plasma
serum.
Armed
with
equipment
progressive
software
solutions,
the
scientific
community
has
shown
that
small
molecules’
roles
living
systems
not
limited
traditional
“building
blocks”
or
“just
fuel”
for
cellular
energy.
As
a
result,
conclusions
based
on
studying
metabolome
finding
practical
reflection
molecular
medicine
better
understanding
of
fundamental
biochemical
processes
systems.
This
review
is
detailed
protocol
metabolomic
analysis.
However,
it
should
support
reader
information
about
achievements
whole
process
metabolic
exploration
human
serum
using
mass
spectrometry
combined
gas
chromatography.
Metabolites,
Journal Year:
2022,
Volume and Issue:
12(3), P. 205 - 205
Published: Feb. 24, 2022
Metabolomics
in
human
serum
samples
provide
a
snapshot
of
the
current
metabolic
state
an
individuum.
Metabolite
concentrations
are
influenced
by
both
genetic
and
environmental
factors.
Concentrations
certain
metabolites
can
further
depend
on
age,
sex,
menopause,
diet
study
participants.
A
better
understanding
these
relationships
is
pivotal
for
planning
metabolomics
studies
involving
subjects
interpretation
their
results.
We
generated
one
largest
single-site
targeted
data
sets
consisting
175
quantified
6872
identified
significantly
associated
with
body
mass
index,
diet,
menopausal
status.
While
most
our
results
agree
previous
large-scale
studies,
we
also
found
novel
associations
including
serotonin
as
sex
BMI-related
metabolite
sarcosine
C2
carnitine
showing
higher
post-menopausal
women.
Finally,
observed
strong
between
consumption
food
items
metabolites,
mostly
phosphatidylcholines
lysophosphatidylcholines.
Most,
strongest,
were
habitual
meat
intake
while
no
significant
fruits,
vegetables,
grain
products.
Summarizing,
reconfirm
findings
from
population-based
independent
cohort.
Together,
will
ultimately
enable
consolidation
which
related
to
BMI,
menopause
well
participants'
diet.
