A multidomain intervention against cognitive decline in an at‐risk‐population in Germany: Results from the cluster‐randomized AgeWell.de trial

Alzheimer s & Dementia, Journal Year: 2023, Volume and Issue: 20(1), P. 615 - 628

Published: Sept. 28, 2023

Abstract INTRODUCTION We investigated the effectiveness of a multidomain intervention to preserve cognitive function in older adults at risk for dementia Germany cluster‐randomized trial. METHODS Individuals with Cardiovascular Risk Factors, Aging, and Dementia (CAIDE) score ≥ 9 aged 60 77 years were recruited. After randomization their general practitioner (GP), patients received (including optimization nutrition medication, physical, social, activity) or health advice GP treatment as usual over 24 months. Primary outcome was global performance (composite z score, based on domain‐specific neuropsychological tests). RESULTS Of 1030 participants baseline, n = 819 completed 24‐month follow‐up assessment. No differences regarding (average marginal effect 0.010, 95% confidence interval: –0.113, 0.133) found between groups follow‐up. Perceived restrictions conduct by COVID‐19 pandemic did not impact effectiveness. DISCUSSION The improve performance. Highlights Overall, no effects detected. improved health‐related quality life total sample. In women, reduced depressive symptoms. during pandemic.

Language: Английский

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The impact of the COVID-19 pandemic on global trade-embodied carbon emissions

Journal of Cleaner Production, Journal Year: 2023, Volume and Issue: 408, P. 137042 - 137042

Published: April 5, 2023

Language: Английский

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Changes in Physical Activity and Sedentary Behavior before and during the COVID-19 Pandemic: A Swedish Population Study

International Journal of Environmental Research and Public Health, Journal Year: 2022, Volume and Issue: 19(5), P. 2558 - 2558

Published: Feb. 23, 2022

Governments have enforced measures to limit the spread of COVID-19 with varying degrees success, which could affect people's physical activity (PA) and sedentary behavior. This study aimed examine changes in PA levels, types PA, behavior Swedish population before during pandemic. Associations between changed levels demographical behavioral determinants were also investigated. In December 2020, 1035 individuals (18-79 years old) completed a survey about their Factors influencing explored. Fifty-one percent sample reported reduced total 18% had no change, 31% increased PA. Overall, organized decreased most increased. The youngest oldest age groups greatest reduction while middle-aged Men larger increase than women. Mental capability was associated change conclusion, this indicates that, pandemic, majority concurrent behavior, may negative health consequences. Interventions are recommended address both specifically strengthen ability perform focusing on groups.

Language: Английский

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Association of physical activity with socio-economic status and chronic disease in older adults in China: cross-sectional findings from the survey of CLASS 2020 after the outbreak of COVID-19

BMC Public Health, Journal Year: 2024, Volume and Issue: 24(1)

Published: Jan. 2, 2024

Abstract Background In 2021, China had a population of 264·01 million individuals over the age 60, indicating high prevalence chronic diseases. Among older adults, physical inactivity (PI) is significant risk factor for However, few studies have been conducted on correlation activity (PA) with economic status, geography and disease risks in Chinese elderly. The objectives this study were to better understand distribution PA among adults its relationship geography, risks. Methods This utilized data from Longitudinal Aging Social Survey (CLASS) 2020, post-COVID-19. employed stratified, multistage, probabilistic sampling approach included 11,396 59 28 provinces China. Data demographics, duration intensity PA, history diseases personalized factors influencing collected via structured interviews by researchers. study, we comprehensive analysis, employing range statistical methods including descriptive Wilcoxon rank-sum tests, Bayesian networks, chi-square tests. Results PI 28·82%. Significant regional differences observed at different intensities. Older residing more economically developed areas likely engage moderate-to-vigorous (MVPA) exhibited longer sedentary behavior. Economic status urban-rural disparities consistently emerged as direct influential across all types. Chronic significantly lower active compared inactive ones. Lack social guidance, family support, personal inclination towards behavior main affecting these could be relatively easily modified. Conclusions living (urban rural) influenced activities Particularly, acted factors. reaching recommended standards risks, highlighting importance improving which are crucial promoting PA.

Language: Английский

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Understanding influences on physical activity participation by older adults: A qualitative study of community-dwelling older adults from the Hertfordshire Cohort Study, UK

PLoS ONE, Journal Year: 2022, Volume and Issue: 17(1), P. e0263050 - e0263050

Published: Jan. 25, 2022

Background The health benefits of physical activity (PA) participation in later life are widely recognised. Understanding factors that can influence the community-dwelling older adults PA is crucial an ageing society. This will be paramount aiding design future interventions to effectively promote this population. main aim qualitative study was explore influences on among people, and secondary gender differences. Methods Qualitative data were collected 2014 by conducting focus group discussions using a semi-structured discussion guide with people resident Hertfordshire, UK. Discussions audio-recorded, transcribed verbatim transcripts analysed thematically. Results Ninety-two participants recruited (47% women; 74–83 years) total 11 groups conducted. Findings indicated six themes appeared affect adults’ PA: past experiences; significant events; getting older; environment; psychological/personal factors; social capital. Overall, findings emphasised role modifiable factors, namely psychological (such as self-efficacy, motivation, outcome expectancy) support engagement). These exerted their own participation, but also mediate effect other largely non-modifiable background ageing-related participants’ engagement life. Conclusion In view these findings, intervention designers could usefully work behavioural scientists for insight how enhance adults. Our suggest build motivation networks have potential indirectly would best achieved developing through working empowering engaging way.

Language: Английский

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A double-blinded, randomized, parallel intervention to evaluate biomarker-based nutrition plans for weight loss: The PREVENTOMICS study

Clinical Nutrition, Journal Year: 2022, Volume and Issue: 41(8), P. 1834 - 1844

Published: June 30, 2022

Growing evidence suggests that biomarker-guided dietary interventions can optimize response to treatment. In this study, we evaluated the efficacy of PREVENTOMCIS platform-which uses metabolomic and genetic information classify individuals into different 'metabolic clusters' create personalized plans-for improving health outcomes in subjects with overweight or obesity.A 10-week parallel, double-blinded, randomized intervention was conducted 100 adults (82 completers) aged 18-65 years, body mass index ≥27 but <40 kg/m2, who were allocated either a diet group (n = 49) control 51). About 60% all food provided free-of-charge. No specific instruction restrict energy intake given. The primary outcome change fat from baseline, by dual X-ray absorptiometry. Other endpoints included weight, waist circumference, lipid profile, glucose homeostasis markers, inflammatory blood pressure, physical activity, stress eating behavior.There significant main effects time (P < 0.01), no effects, time-by-group interactions, for (personalized: -2.1 [95% CI -2.9, -1.4] kg; control: -2.0 -2.7, -1.3] kg) weight -3.1 -4.1, -2.1] -3.3 -4.2, -2.4] kg). difference between groups -0.1 kg (95% -1.2, 0.9 kg, P 0.77). Both diets resulted improvements insulin resistance there differences groups.Personalized plans did not result greater benefits over generic, generally healthy diet, clinical trial. Further studies are required establish soundness precision nutrition approaches, translate science clinically relevant advice reduce burden obesity its comorbidities.ClinicalTrials.gov registry (NCT04590989).

Language: Английский

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Unintended Consequences of COVID-19 Non-Pharmaceutical Interventions (NPIs) for Population Health and Health Inequalities

International Journal of Environmental Research and Public Health, Journal Year: 2023, Volume and Issue: 20(7), P. 5223 - 5223

Published: March 23, 2023

Since the start of COVID-19 pandemic in early 2020, governments around world have adopted an array measures intended to control transmission SARS-CoV-2 virus, using both pharmaceutical and non-pharmaceutical interventions (NPIs). NPIs are public health that do not rely on vaccines or medicines include policies such as lockdowns, stay-at-home orders, school closures, travel restrictions. Although intention was slow viral transmission, emerging research indicates these also had unintended consequences for other aspects health. Hence, we conducted a narrative review studies investigating NPIs, with particular emphasis mental lifestyle risk factors non-communicable diseases (NCD): physical activity (PA), overweight obesity, alcohol consumption, tobacco smoking. We reviewed scientific literature combinations search terms ‘COVID-19′, ‘pandemic’, ‘lockdowns’, ‘mental health’, ‘physical activity’, ‘obesity’. were found considerable adverse health, activity, obesity. The impacts consumption varied greatly within between studies. variability different groups implies increased inequalities by age, sex/gender, socioeconomic status, pre-existing lifestyle, place residence. In conclusion, proper assessment use attempts spread should be weighed against potential Our findings relevance future preparedness response teams.

Language: Английский

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Work from home and the association with sedentary behaviors, leisure-time and domestic physical activity in the ELSA-Brasil study

BMC Public Health, Journal Year: 2023, Volume and Issue: 23(1)

Published: Feb. 10, 2023

Abstract Background Work from home (WFH) can impact workers´ sedentary behaviors and levels of physical activity. The aim this study was to estimate the association between WFH behaviors, leisure-time domestic activities during COVID-19 pandemic verify whether age sex may act as effect modifiers. Methods We conducted a cross-sectional 2544 participants in supplementary on Longitudinal Study Adult Health (ELSA-Brasil) July 2020 February 2021. assessed screen time (≤ 8 h/day versus > h/day), accumulated sitting h/day) typical day, (active inactive, according World Organization recommendations) (low high, median) activity, using International Physical Activity Questionnaire (IPAQ), before social distancing. Logistic regression models were used. Results Participants that working distancing showed increased odds greater than (OR = 3.12; 95%CI: 2.32–4.20 OR 2.68; 2.02–3.56, respectively) higher high activity 1.29; 0.99–1.67) when compared those not home. There no 0.99, 0.75,1.31). Age an modifier Older people inactivity 1.84, 1.07,3.16) 1.92, 1.12,3.27) older Conclusion associated with behavior In people, As are consistently negatively health, it is important discuss policies manage allow pauses performance hours work within preestablished limits reduce behavior. addition, individuals home, especially should be encouraged engage form health promotion.

Language: Английский

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Increasing Incidence of Pickleball Injuries Presenting to US Emergency Departments: A 10-year Epidemiologic Analysis of Mechanisms and Trends

Orthopaedic Journal of Sports Medicine, Journal Year: 2025, Volume and Issue: 13(1)

Published: Jan. 1, 2025

Background: Pickleball is one of the fastest-growing sports in United States. It popular among seniors but has recently grown across all age groups. As pickleball gained interest, its corresponding injury burden also increased. Purpose/Hypothesis: The purpose this study was to identify pickleball-related trends and underlying mechanisms different groups presenting US emergency departments. hypothesized that (1) injuries would increase significantly between 2013 2022, (2) older have greatest frequency injury, (3) falls be most common mechanism injury. Study Design: Descriptive epidemiology study. Methods: National Electronic Injury Surveillance System (NEISS) queried for January 1, 2013, December 31, 2022. demographic information, site, diagnosis were recorded, case narratives reviewed mechanism. statistical sample weight assigned NEISS cases by hospital used calculate national estimates (NEs). over time evaluated linear regression. Results: A total 1110 representing 66,350 nationally estimated included. mean 64 ± 14.7 years (range, 4-93 years). Most occurred those aged 65 80 (NEISS = 643; NE 40,507 [61.1%]), followed 35 349; 20,785 [31.3%]). Falls overall 699; 43,434 [65.5%]). However, being hit with a paddle twist/inversion ages 0 17 18 34 years, respectively. Fractures 363; 21,703 [32.7%]), strains/sprains 327; 20,419 [30.8%]). Also, 69.1% fractures female players. wrist injured, accounting 12.7% injuries. Significant increases seen ( P < .001) .05). Conclusion: There significant arising from fall. Notably, decreased 14% 2019 2020 rose again 41% 2021 during coronavirus pandemic. Older players disproportionately presented department Increased awareness comprehensive prevention initiatives may warranted address considerable prevalence overuse/strain

Language: Английский

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Functional limitations in 2004–22 among Europeans aged 55–69 years: time trends according to labor market group and impacts of the COVID-19 pandemic

European Journal of Public Health, Journal Year: 2025, Volume and Issue: unknown

Published: April 16, 2025

Abstract In terms of work ability, impacts the Coronavirus disease 2019 (COVID-19) pandemic on functional ability warrant investigation. The aim is to explore trends in limitations 2004–22 focusing among older working-aged Europeans different labor market groups and at levels COVID-19 stringency policies. Data come from Survey Health, Ageing Retirement Europe (SHARE) collected 2004–22. Individuals aged 55–69 years 27 countries were included (N = 245 060). Outcome was (Global Activity Limitation Index). Generalized estimating equations used analyze time within 2004–22, likelihood increased slightly men but remained same women. Functional more likely with low moderate as compared high (which represents mostly Southern Europe) both women men. During ∼1st year pandemic, decreased especially stringency. Decreases observed all groups. ∼2nd not statistically significantly most Policymakers should be aware policy decisions while pursuing prolong careers. Further investigation required verify our findings underlying reasons behind decreases after pandemic.

Language: Английский

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