Impact of Acrylamide on Crawling Activity of Three Drosophila Strains: Larval Speed and Contraction Number

IOP Conference Series Earth and Environmental Science, Journal Year: 2025, Volume and Issue: 1439(1), P. 012012 - 012012

Published: Jan. 1, 2025

Abstract Acrylamide is a chemical compound that can be formed in some foods cooked at high temperatures. This substance has the potential to cause various health problems, although publications report findings contrary. The purpose of this study was analyze effect acrylamide consumption and strain type on crawling performance Drosophila melanogaster larvae: speed number beats. experimental divided into groups without consumption, 24 mg/kg bw/day 48 bw/day. In parameter, only factor had significant (F = 24.580, p < 0.001), while 0.706, 0.519) interaction factors did not have 0.782, 0.565). Strain also twitches 4.555, 0.043), administration 0.731, 0.508) two 0.426, 0.787) effect. results indicate does beats D. larvae, differences between strains impact. These implications for assessing risk toxicity human health. Genetic variation individuals influence individual sensitivity exposure.

Language: Английский

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Tyramine-Mediated Hyperactivity Modulates the Dietary Habits in Helicoverpa armigera

Journal of Chemical Ecology, Journal Year: 2024, Volume and Issue: 50(9-10), P. 453 - 464

Published: June 18, 2024

Language: Английский

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PROM1-mediated cell signal transduction in cancer stem cells and hepatocytes

BMB Reports, Journal Year: 2023, Volume and Issue: 56(2), P. 65 - 70

Published: Jan. 27, 2023

Prominin-1 (PROM1), also called CD133, is a penta-span transmembrane protein that localized in membrane protrusions, such as microvilli and filopodia. It known to be expressed cancer stem cells various progenitor of bone marrow, liver, kidney, intestine. Accumulating evidence has revealed PROM1 multiple functions organs, eye, tooth, peripheral nerve, associating with molecular partners. regulates PKA-induced gluconeogenesis, TGFβ-induced fibrosis, IL-6-induced regeneration the Radixin, SMAD7, GP130, respectively. In addition, necessary maintain cell properties by activating PI3K β-Catenin. PROM1-deficienct mice show distinct phenotypes eyes, brain, nerves, tooth. Here, we discuss recent findings PROM1-mediated signal transduction. [BMB Reports 2023; 56(2): 65-70].

Language: Английский

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A FMRFamide-like neuropeptide FLP-12 signaling regulates head locomotive behaviors in C. elegans

Molecules and Cells, Journal Year: 2024, Volume and Issue: unknown, P. 100124 - 100124

Published: Oct. 1, 2024

Language: Английский

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A comparison study of pathological features and drug efficacy between Drosophila models of C9orf72 ALS/FTD

Molecules and Cells, Journal Year: 2023, Volume and Issue: 47(1), P. 100005 - 100005

Published: Dec. 22, 2023

Amyotrophic lateral sclerosis is a devastating neurodegenerative disease with complex genetic basis, presenting both in familial and sporadic forms. The hexanucleotide (G

Language: Английский

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HLH-30/TFEB mediates sexual dimorphism in immunity in caenorhabditis elegans

Autophagy, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 15

Published: July 4, 2024

Sexual dimorphism affects various biological functions, including immune responses. However, the mechanisms by which sex alters immunity remain largely unknown. Using

Language: Английский

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Identification of a cryptic functional apolipophorin-III domain within the Prominin-1 gene of Litopenaeus vannamei

Comparative Biochemistry and Physiology Part B Biochemistry and Molecular Biology, Journal Year: 2023, Volume and Issue: 270, P. 110928 - 110928

Published: Dec. 2, 2023

Language: Английский

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