Addictive Behaviors Reports,
Journal Year:
2023,
Volume and Issue:
19, P. 100521 - 100521
Published: Nov. 30, 2023
The
landscape
of
availability,
policies,
and
norms
around
e-cigarette
use
cessation
has
changed
rapidly
in
the
last
few
years.
There
is
also
high
interest
quitting
vaping
among
teens
young
adults.
Understanding
motivation
those
who
want
to
quit
important
for
effective
intervention
development.
This
analysis
compares
user-submitted
reasons
(RFQ)
from
2022
a
previous
2019
determine
whether
motivations
have
shifted
people.
We
reviewed
2000
RFQ
submissions
users
enrolled
text
message
program
2022.
Each
response
was
coded
by
≥
2
researchers
categorized
into
one
16
themes.
Findings
were
compared
using
item-wise
comparisons.
most
frequent
health
(56.1%),
social
influence
(15.8%),
other
(11.7%).
In
comparison
2019,
remained
top
reason,
but
rank
order
all
shifted.
Theme
prevalence
significantly,
with
cost
decreasing
increasing.
Among
health-related
sub-categories,
current
mental
increased
submissions.
people
between
observed
greater
concern
about
health,
possibly
experiencing
negative
impacts
or
awareness
these
impacts.
lower
may
reflect
widespread
availability
cheaper
e-cigarettes.
likely
change
fluctuating
should
be
considered
interventions,
promotional
campaigns,
policy.
Drug Testing and Analysis,
Journal Year:
2023,
Volume and Issue:
16(2), P. 127 - 161
Published: June 2, 2023
Abstract
Since
the
early
2000s,
there
has
been
a
turmoil
on
global
illicit
cannabinoid
market.
Parallel
to
legislative
changes
in
some
jurisdictions
regarding
herbal
cannabis,
unregulated
and
cheap
synthetic
cannabinoids
with
astonishing
structural
diversity
have
emerged.
Recently,
semi‐synthetic
manufactured
from
hemp
extracts
by
simple
chemical
transformations
also
appeared
as
recreational
drugs.
The
burst
of
these
into
market
was
sparked
United
States,
where
cultivation
industrial
restarted.
By
now,
hemp‐derived
cannabidiol
(CBD),
initially
blockbuster
product
its
own,
became
“precursor”
such
hexahydrocannabinol
(HHC),
which
drug
2021.
synthesis
cannabimimetic
activity
HHC
were
first
reported
eight
decades
ago
quest
for
psychoactive
principles
marijuana
hashish.
Current
large‐scale
manufacture
is
based
CBD
extract,
converted
cyclization
Δ
8
/Δ
9
‐THC
mixture,
followed
catalytic
hydrogenation
afford
mixture
(9
R
)‐HHC
S
epimers.
Preclinical
studies
indicate
that
THC‐like
pharmacological
properties.
animal
metabolism
partially
clarified.
human
pharmacology
including
yet
be
investigated,
(immuno)analytical
methods
rapid
detection
or
metabolites
urine
are
lacking.
Herein,
legal
background
revitalization
cultivation,
available
information
chemistry,
analysis,
related
analogs,
acetate
(HHC‐O)
reviewed.
Journal of Allergy and Clinical Immunology,
Journal Year:
2024,
Volume and Issue:
154(4), P. 835 - 846
Published: Aug. 24, 2024
Because
of
the
disproportionate
amount
time
that
people
spend
indoors
and
complexities
air
pollutant
exposures
found
there,
indoor
pollution
is
a
growing
concern
for
airway
health.
Both
infiltration
outdoor
into
space
sources
(such
as
smoke
from
tobacco
products,
cooking
or
heating
practices
combustion
associated
fuels,
household
materials)
contribute
to
unique
exposure
mixtures.
Although
there
substantial
literature
on
chemistry
pollution,
research
focused
health
effects
only
beginning
emerge
remains
an
important
area
need
protect
public
We
provide
review
emerging
spanning
past
3
years
relating
health,
with
specific
focus
impact
either
individual
common
lower
airways.
Factors
defining
susceptibility
and/or
vulnerability
are
reviewed
consideration
priority
populations
modifiable
risk
factors
may
be
targeted
advance
equity.
Scientific Reports,
Journal Year:
2024,
Volume and Issue:
14(1)
Published: Aug. 15, 2024
Secondhand
vaping
exposure
is
an
emerging
public
health
concern
that
remains
understudied.
In
this
study,
saliva
and
exhaled
emissions
from
ENDS
users
(secondhand)
non-ENDS
(baseline)
were
collected,
firsthand
generated
using
automated
aerosol
generation
system
programmed
to
simulate
puffing
topography
profiles
collected
users.
Particulate
concentrations
sizes
along
with
volatile
organic
compounds
characterized.
We
revealed
metrics
as
potential
mediators
of
secondhand
particle
chemical
exposures,
well
metabolic
respiratory
outcomes.
Particle
deposition
modeling
while
displayed
smaller
deposited
mass,
total
pulmonary
fractions
higher
than
levels,
possibly
due
emission
diameters.
Lastly,
untargeted
metabolomic
profiling
salivary
biomarkers
lung
injury
exposures
early
indicators
distress
may
also
be
relevant
in
bystanders
exposed
scenarios.
By
leveraging
toxicology,
we
identified
10
metabolites,
including
leukotriene
D4,
could
potentially
serve
for
use,
estimation,
the
prediction
vaping-related
disease.
This
study
highlights
characterization
behavior
important
component
advancing
our
understanding
effects
bystanders.
Toxics,
Journal Year:
2023,
Volume and Issue:
11(3), P. 278 - 278
Published: March 18, 2023
Although
combustible
cigarette
smoking
rates
have
declined
in
recent
years,
alternative
tobacco
product
use,
particularly
electronic
use
("vaping"),
has
increased
among
young
adults.
Recent
studies
indicate
that
vaping
during
pregnancy
is
on
the
rise,
possibly
due
to
perception
it
a
safer
smoking.
However,
e-cigarette
aerosols
may
contain
several
newer,
potentially
toxic
compounds,
including
some
known
developmental
toxicants
adversely
impact
both
mother
and
fetus.
there
paucity
of
examined
effects
pregnancy.
While
adverse
perinatal
outcomes
are
well
established,
specific
risks
associated
with
inhaling
requires
more
research.
In
this
article,
we
discuss
existing
evidence
knowledge
gaps
Studies
investigate
vaping-associated
systemic
exposure
its
(i.e.,
biomarker
analyses)
maternal
neonatal
clinical
health
needed
reach
robust
conclusions.
We
emphasize
need
go
beyond
comparative
cigarettes,
advocate
for
research
objectively
evaluates
safety
e-cigarettes
other
products.
Chemical Research in Toxicology,
Journal Year:
2024,
Volume and Issue:
37(8), P. 1415 - 1427
Published: July 30, 2024
The
outbreak
of
e-cigarette
or
vaping
use-associated
lung
injury
(EVALI)
in
the
United
States
2019
led
to
a
total
2807
hospitalizations
with
68
deaths.
While
exact
causes
this
vaping-related
illness
are
still
being
debated,
laboratory
analyses
products
from
victims
EVALI
have
shown
that
vitamin
E
acetate
(VEA),
an
additive
some
tetrahydrocannabinol
(THC)-containing
products,
is
strongly
linked
outbreak.
Because
its
similar
appearance
and
viscosity
pure
THC
oil,
VEA
was
used
as
diluent
agent
cannabis
oils
illicit
markets.
A
potential
mechanism
for
may
involve
VEA's
thermal
decomposition
product,
ketene,
highly
poisonous
gas,
generated
under
conditions.
In
study,
novel
approach
developed
evaluate
ketene
production
measurable
temperature
conditions
real-world
devices.
Ketene
aerosols
captured
by
two
different
chemical
agents
analyzed
gas
chromatography–mass
spectrometry
(GC-MS)
liquid
chromatography
tandem
mass
(LC-MS/MS).
LC-MS/MS
method
takes
advantage
high
sensitivity
specificity
appears
be
more
suitable
than
GC-MS
analysis
large
batches
samples.
Our
results
confirmed
formation
when
vaped.
increased
repeat
puffs
showed
correlation
temperatures
(200
500
°C)
measured
within
Device
battery
power
strength,
which
affects
heating
temperature,
plays
important
role
formation.
addition
organic
oxidant
duroquinone
also
obtained
another
degradation
product
VEA.
not
detected
vaped
same
conditions,
confirming
importance
group
generation.
Cermin Dunia Kedokteran,
Journal Year:
2025,
Volume and Issue:
52(1), P. 56 - 61
Published: Jan. 13, 2025
Adanya
risiko
kesehatan
merokok
menyebabkan
perusahaan
mengembangkan
dan
mengiklankan
produk
nikotin
alternatif,
seperti
e-cigarettes
“heat-not-burn”
(HnB)
tanpa
membakar
tembakau.
United
States’
Federal
Drug
Administration
(US
FDA)
menyetujui
peredaran
komersil
I
Quit
Ordinary
Smoking
(IQOS)
di
Amerika
Serikat.
Produk
tembakau
HnB
memanaskan
(hingga
350°C)
untuk
menghasilkan
aerosol
yang
dihirup
membakarnya
pada
suhu
jauh
lebih
tinggi
(800°C).
Laporan
menunjukkan
37%
pengguna
mengalami
setidaknya
satu
gejala,
paling
umum
adalah
sakit
tenggorokan
(25,1%)
diikuti
oleh
rasa
tidak
nyaman
mata
(22,3%).
Keyakinan
sebagai
alternatif
mereduksi
dampak
rokok
konvensional
sepenuhnya
benar.
Tembakau
tetap
dapat
memberikan
buruk
terhadap
kesehatan.
JAAPA,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Feb. 4, 2025
ABSTRACT
Electronic
cigarettes
(e-cigarettes)
are
the
most
commonly
used
tobacco
product
by
adolescents.
This
article
describes
harmful
effects
of
e-cigarette
use
in
adolescents
and
how
to
evaluate
for
severity
nicotine
dependence.
It
also
provides
an
overview
treatment
approaches,
including
behavioral
interventions,
contingency
pharmacologic
options,
school-based
programs,
combination
emerging
transcranial
magnetic
stimulation.
