Silver Nanoparticles in Therapeutics and Beyond: A Review of Mechanism Insights and Applications DOI Creative Commons
Furkan Eker, Hatice Duman, Emir Akdaşçi

et al.

Nanomaterials, Journal Year: 2024, Volume and Issue: 14(20), P. 1618 - 1618

Published: Oct. 10, 2024

Silver nanoparticles (NPs) have become highly promising agents in the field of biomedical science, offering wide therapeutic potential due to their unique physicochemical properties. The characteristics silver NPs, such as higher surface-area-to-volume ratio, make them ideal for a variety biological applications. They are easily processed thanks large surface area, strong plasmon resonance (SPR), stable nature, and multifunctionality. With an emphasis on mechanisms action, efficacy, prospective advantages this review attempts give thorough overview numerous applications these particles. utilization NPs diagnostics, bioimaging biosensing, well functions interventions antimicrobial therapies, cancer therapy, diabetes treatment, bone repair, wound healing, investigated. underlying processes by which exercise effects, oxidative stress induction, apoptosis, microbial cell membrane rupture, explored. Furthermore, toxicological concerns regulatory issues discussed, present difficulties restrictions related application medicine.

Language: Английский

Synthesis, Characterization and Biomedical Application of Silver Nanoparticles DOI Open Access

Ashwini Naganthran,

Gayathiri Verasoundarapandian, Farah Eryssa Khalid

et al.

Materials, Journal Year: 2022, Volume and Issue: 15(2), P. 427 - 427

Published: Jan. 6, 2022

Silver nanoparticles (AgNPs) have been employed in various fields of biotechnology due to their proven properties as an antibacterial, antiviral and antifungal agent. AgNPs are generally synthesized through chemical, physical biological approaches involving a myriad methods. As each approach confers unique advantages challenges, trends analysis literature for the synthesis using different types were also reviewed bibliometric approach. A sum 10,278 publications analyzed on annual numbers publication relating biological, chemical or from 2010 2020 Microsoft Excel applied Scopus database. Furthermore, another clustering mapping software used study occurrences author keywords biomedical applications biosynthesized total collection 224 documents found, sourced articles, reviews, book chapters, conference papers reviews. provides excellent, dependable, effective solution seven major concerns: antiviral, anticancer, bone healing, cement, dental wound healing. In recent years, sector anticancer properties. This review discussed synthesis, how characterized field.

Language: Английский

Citations

208

Metal and metal oxide-based antiviral nanoparticles: Properties, mechanisms of action, and applications DOI
Mehran Alavi, Pragathi Kamarasu, David Julian McClements

et al.

Advances in Colloid and Interface Science, Journal Year: 2022, Volume and Issue: 306, P. 102726 - 102726

Published: June 27, 2022

Language: Английский

Citations

97

Combined bactericidal process of lignin and silver in a hybrid nanoparticle on E. coli DOI Open Access

Fangli Ran,

Chenyu Li,

Zhenxin Hao

et al.

Advanced Composites and Hybrid Materials, Journal Year: 2022, Volume and Issue: 5(3), P. 1841 - 1851

Published: April 12, 2022

Language: Английский

Citations

81

Inorganic nanoparticles in dermopharmaceutical and cosmetic products: Properties, formulation development, toxicity, and regulatory issues DOI Creative Commons
Filipa Mascarenhas‐Melo, Ankita Mathur, Sivasubramanian Murugappan

et al.

European Journal of Pharmaceutics and Biopharmaceutics, Journal Year: 2023, Volume and Issue: 192, P. 25 - 40

Published: Sept. 20, 2023

The use of nanotechnology strategies is a current hot topic, and research in this field has been growing significantly the cosmetics industry. Inorganic nanoparticles stand out context for their distinctive physicochemical properties, leading particular to an increased refractive index absorption capacity giving them broad potential cutaneous applications making special interest dermopharmaceutical cosmetic purposes. This performance responsible its heavy inclusion manufacture skin health products such as sunscreens, lotions, beauty creams, ointments, makeup, others. In particular, suitable bandgap energy characteristics allow be used photocatalytic semiconductors. They provide excellent UV absorption, commonly known filters, are wide worldwide sunscreen formulations without undesirable white residue after consumer application. addition, based on inorganic have several additional relevant formulation development, being less expensive compared other nanomaterials, having greater stability, ensuring irritation, itching, propensity allergies. review will address detail main products, titanium dioxide, zinc oxide, silicon silver, gold, copper, aluminum nanoparticles, nanocrystals, quantum dots, reporting characteristics, but also intrinsic properties that contribute type formulations. Safety issues regarding toxicity studies, both humans environment, well regulatory affairs associated with dermopharmaceuticals cosmetics, addressed.

Language: Английский

Citations

48

Silver Nanoparticles in Dental Applications: A Descriptive Review DOI Creative Commons
Sreekanth Kumar Mallineni,

Srinivasulu Sakhamuri,

Sree Lalita Kotha

et al.

Bioengineering, Journal Year: 2023, Volume and Issue: 10(3), P. 327 - 327

Published: March 5, 2023

Silver nanoparticles have been a recent focus of many researchers in dentistry, and their potential uses benefits drawn attention dentistry medicine. The fabrication utilization nanoscale substances structures are at the core rapidly developing areas nanotechnology. They often used dental industry because they prevent bacteria from making nanoparticles, oxides, biofilms. also stop metabolism bacteria. (AgNPs) type zero-dimensional material with different shapes. Dentistry has to keep up changing patient needs new technology. can be for disinfection preventing infections oral cavity. One most interesting metallic biomedical applications is silver (AgNPs). field found promising elimination plaque tartar, as well bacterial fungal mouth. incorporation AgNPs into materials shown significantly enhance patients’ health, leading widespread use. This review focuses on AgNP synthesis, chemical properties, biocompatibility, various fields, biomaterials dentistry. With an emphasis aspects related inclusion this descriptive paper intends address developments

Language: Английский

Citations

44

Silver Nanoparticles: A Comprehensive Review of Synthesis Methods and Chemical and Physical Properties DOI Creative Commons
Hatice Duman, Furkan Eker, Emir Akdaşçi

et al.

Nanomaterials, Journal Year: 2024, Volume and Issue: 14(18), P. 1527 - 1527

Published: Sept. 20, 2024

Recently, silver nanoparticles (NPs) have attracted significant attention for being highly desirable nanomaterials in scientific studies as a result of their extraordinary characteristics. They are widely known effective antibacterial agents that capable targeting wide range pathogens. Their distinct optical characteristics, such localized surface plasmon resonance, enlarge utilization, particularly the fields biosensing and imaging. Also, capacity to control charge modify them using biocompatible substances offers improved durability specific interactions with biological systems. Due exceptional stability minimal chemical reactivity, NPs suitable diverse array applications. These produced through chemical, biological, physical processes, each which has advantages disadvantages. Chemical techniques often encounter issues complicated purification, reactive substances, excessive energy usage. However, eco-friendly approaches exist, even though they require longer processing times. A key factor affecting stability, size distribution, purity is synthesis process selected. This review focuses on how essential it choose appropriate method order optimize characteristics use NPs.

Language: Английский

Citations

34

Green synthesis, characterization, antidiabetic, antioxidant and antibacterial applications of silver nanoparticles from Syzygium caryophyllatum (L.) Alston leaves DOI
Santosh Mallikarjun Bhavi, Bothe Thokchom, Megha B. Abbigeri

et al.

Process Biochemistry, Journal Year: 2024, Volume and Issue: 145, P. 89 - 103

Published: June 17, 2024

Language: Английский

Citations

19

Metal-Based Nanoparticles for Cardiovascular Diseases DOI Open Access
Alexandru Scafa‐Udriște,

Alexandra Cristina Burdușel,

Adelina-Gabriela Niculescu

et al.

International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 25(2), P. 1001 - 1001

Published: Jan. 13, 2024

Globally, cardiovascular diseases (CVDs) are the leading cause of death and disability. While there many therapeutic alternatives available for management CVDs, majority classic strategies were found to be ineffective at stopping or significantly/additionally slowing progression these diseases, they had unfavorable side effects. Numerous metal-based nanoparticles (NPs) have been created overcome limitations, demonstrating encouraging possibilities in treatment CVDs due advancements nanotechnology. Metallic nanomaterials, including gold, silver, iron, come various shapes, sizes, geometries. NPs generally smaller more specialized physical, chemical, biological properties. Metal-based may forms, such as nanoshells, nanorods, nanospheres, studied most. Massive potential applications metal nanomaterial structures include supporting molecular imaging, serving drug delivery systems, enhancing radiation-based anticancer therapy, supplying photothermal transforming effects thermal being compounds with bactericidal, fungicidal, antiviral qualities that helpful diseases. In this context, present paper aims review relevant oxide creating an up-to-date framework aids researchers developing efficient strategies.

Language: Английский

Citations

17

Silver nanoparticle functionalized by glutamine and conjugated with thiosemicarbazide induces apoptosis in colon cancer cell line DOI Creative Commons

Hadi Taati,

Helia Sangani,

Arash Davoudi

et al.

Scientific Reports, Journal Year: 2024, Volume and Issue: 14(1)

Published: Feb. 15, 2024

Abstract The high mortality rate of colon cancer indicates the insufficient efficacy current chemotherapy. Thus, discussion on engineered metal nanoparticles in treatment disease has been considered. In this study, silver were functionalized with glutamine and conjugated thiosemiccarbazide. Then, anticancer mechanism Ag@Gln-TSC NPs a cell line (SW480) was investigated. Characterizing by FT-IR, XRD, EDS-mapping, DLS, zeta potential, SEM TEM microscopy revealed that correctly synthesized, particles spherical, surface charge − 27.3 mV, thermal stability low agglomeration level. Using MTT assay we found significantly more toxic for cells than normal fibroblast IC 50 88 186 µg/mL, respectively. Flow cytometry analysis showed treating leads to considerable increase frequency apoptotic (85.9% cells) increased cycle arrest at S phase. Also, several features, including hyperactivity caspase-3 (5.15 folds), expression CASP8 gene (3.8 nuclear alterations noticed nanoparticle treated cells. Furthermore, caused significant down-regulation HULC Lnc-RNA PPFIA4 oncogene 0.3 0.6 folds, Overall, work can effectively inhibit through activation pathways, feature be considered studies field treatment.

Language: Английский

Citations

16

A review on green synthesis of silver nanoparticles (SNPs) using plant extracts: a multifaceted approach in photocatalysis, environmental remediation, and biomedicine DOI Creative Commons

Sehar Shahzadi,

Sehrish Fatima, Qurat Ul Ain

et al.

RSC Advances, Journal Year: 2025, Volume and Issue: 15(5), P. 3858 - 3903

Published: Jan. 1, 2025

A sustainable and viable alternative for conventional chemical physical approaches is the green production of silver nanoparticles (SNPs) using plant extracts.

Language: Английский

Citations

6