Critical Reviews in Biotechnology,
Journal Year:
2023,
Volume and Issue:
44(2), P. 319 - 336
Published: Jan. 2, 2023
Phloroglucinol
and
derived
compounds
comprise
a
huge
class
of
secondary
metabolites
widely
distributed
in
plants
brown
algae.
A
vast
array
biological
activities,
including
antioxidant,
anti-inflammatory,
antimicrobial,
anticancer
has
been
associated
to
this
compounds.
In
review,
the
available
data
on
antiviral
antibacterial
capacity
phloroglucinols
have
analyzed.
Some
these
derivatives
show
important
antimicrobial
properties
vitro.
Phloroglucinols
shown
be
effective
against
viruses,
such
as
human
immunodeficiency
virus
(HIV),
herpes
or
enterovirus,
preliminary
through
docking
analysis
suggest
that
they
can
SARS-CoV-19.
Also,
some
effects
diverse
bacteria
strains,
Bacillus
subtilis
Staphylococcus
aureus,
(semi)synthetic
development
novel
led
with
significantly
increased
activity.
However,
therapeutic
use
is
hindered
by
absence
vivo
studies
scarcity
information
their
mechanisms
action,
hence
further
research
efforts
are
required.
On
basis
consideration,
our
work
aims
gather
regarding
efficacy
natural-occurring
synthetic
phloroglucinol
agents
pathogens,
which
published
during
last
three
decades.
The
recollection
results
reported
review
represents
valuable
source
updated
will
potentially
help
researchers
agents.
iScience,
Journal Year:
2024,
Volume and Issue:
27(3), P. 109176 - 109176
Published: Feb. 9, 2024
Brown
macroalgae
are
colonized
by
diverse
microorganisms
influencing
the
physiology
of
their
host.
However,
cell-cell
interactions
within
surface
microbiome
(epimicrobiome)
largely
unexplored,
despite
significance
specific
chemical
mediators
in
maintaining
host-microbiome
homeostasis.
In
this
study,
combining
liquid
chromatography
coupled
to
mass
spectrometry
(LC-MS)
analysis
and
bioassays,
we
demonstrated
that
widely
fungal
epimicrobiota
brown
alga
Applied Sciences,
Journal Year:
2022,
Volume and Issue:
13(1), P. 157 - 157
Published: Dec. 22, 2022
Throughout
the
ages,
macroalgae
have
provided
humankind
with
elements
beneficial
to
human
health,
and
often
bioactive
abilities.
Yet,
while
today
we
fully
acknowledge
such
potential,
especially
that
of
most
widely
known
species,
an
even
greater
number
species
remain
unaknowledged.
This
holds
particularly
true
for
highly
diverse
phylum
Rhodophyta
(red
seaweeds)
and,
therefore,
present
study
aims
unveil
antioxidant
antimicrobial
potential
twelve
red
seaweed
collected
in
central
Portugal.
Results
obtained
from
assays
ABTS
TPC
highlighted
high
scavenging
capacity
coralline
algae
Corallina
officinalis,
Ellisolandia
elongata
Amphiroa
rigida,
phenolic
content
Porphyra
umbilicalis,
whereas
analyses
through
MIC
determination
emphasized
activities
Sphaerococcus
coronopifolius
Mesophyllum
lichenoides
against,
respectively,
Bacillus
subtilis
Saccharomyces
cerevisiae.
raised
awareness
waiting
be
discovered
regarding
less
as
rigida
lichenoides.
Therefore,
believe
this
provides
extra
steps
pinpointing
encouraging
further
studies
tailored
toward
a
biotechnological
perspective,
ultimately,
influencing
current
perspectives
exploration
seaweeds.
Critical Reviews in Biotechnology,
Journal Year:
2023,
Volume and Issue:
44(2), P. 319 - 336
Published: Jan. 2, 2023
Phloroglucinol
and
derived
compounds
comprise
a
huge
class
of
secondary
metabolites
widely
distributed
in
plants
brown
algae.
A
vast
array
biological
activities,
including
antioxidant,
anti-inflammatory,
antimicrobial,
anticancer
has
been
associated
to
this
compounds.
In
review,
the
available
data
on
antiviral
antibacterial
capacity
phloroglucinols
have
analyzed.
Some
these
derivatives
show
important
antimicrobial
properties
vitro.
Phloroglucinols
shown
be
effective
against
viruses,
such
as
human
immunodeficiency
virus
(HIV),
herpes
or
enterovirus,
preliminary
through
docking
analysis
suggest
that
they
can
SARS-CoV-19.
Also,
some
effects
diverse
bacteria
strains,
Bacillus
subtilis
Staphylococcus
aureus,
(semi)synthetic
development
novel
led
with
significantly
increased
activity.
However,
therapeutic
use
is
hindered
by
absence
vivo
studies
scarcity
information
their
mechanisms
action,
hence
further
research
efforts
are
required.
On
basis
consideration,
our
work
aims
gather
regarding
efficacy
natural-occurring
synthetic
phloroglucinol
agents
pathogens,
which
published
during
last
three
decades.
The
recollection
results
reported
review
represents
valuable
source
updated
will
potentially
help
researchers
agents.