Green synthesis, characterization, and in vitro and in vivo biological screening of iron oxide nanoparticles (Fe3O4) generated with hydroalcoholic extract of aerial parts of Euphorbia milii DOI Creative Commons
Abdur Rauf, Zubair Ahmad, Haiyuan Zhang

et al.

Green Processing and Synthesis, Journal Year: 2024, Volume and Issue: 13(1)

Published: Jan. 1, 2024

Abstract In this work, iron oxide nanoparticles (IONPs) were synthesized using green methods. The structural morphological and optical properties of (NPs) investigated by scanning electron microscopy (SEM), X-ray diffraction (XRD), ultraviolet–visible spectroscopy, Fourier transform infrared spectroscopy. Based on the SEM analysis, spherical NPs with a size distribution in range 50–70 nm simulated slight variations shapes, corresponding XRD was calculated. calculated patterns then averaged. Well-defined crystalline structure single-phase spinel shape IONPs observed. vitro vivo biological activities hydroalcoholic extract Euphorbia milii ’s aerial parts studied. antibacterial effects evaluated against Staphylococcus aureus , enzyme inhibitory E. various enzymes assessed. demonstrated significant activity urease (89.09% inhibition), α-glucosidase (72.87% carbonic anhydrase II (87.09% xanthine oxidase (85.09% inhibition). also exhibited considerable inhibition these enzymes. IC 50 values for urease, α-glucosidase, II, 26.09, 59.09, 0.18, 7.71 µg·mL −1 respectively. anticancer crude evaluated. minimum recorded MDR 2780AD, i.e., 0.85 (extract) 0.54 (IONPs). Both tested samples found to be ( p < 0.001) analgesic anti-inflammatory. contrast, sedative at all doses, showed 0.01) effect higher doses only.

Language: Английский

Eco-friendly synthesis of ZnO, CuO, and ZnO/CuO nanoparticles using extract of spent Pleurotus ostreatus substrate, and their antioxidant and anticancer activities DOI Creative Commons

Simangele C. Ngwenya,

Nkanyiso J. Sithole, Khosi Ramachela

et al.

Discover Nano, Journal Year: 2025, Volume and Issue: 20(1)

Published: Feb. 13, 2025

Abstract Biosynthesis techniques for nanomaterials have advanced significantly, promoting eco-friendly synthesis chemistry as a sustainable alternative to conventional methods. This study presents novel and environmentally friendly approach synthesizing nanoparticulate ZnO, CuO, ZnO/CuO nanocomposites using aqueous extracts of Pleurotus ostreatus spent substrate, is reported. The structural, optical, morphological properties the synthesized NPs were analysed. A hexagonal phase ZnO monoclinic CuO obtained according X-ray diffraction analysis. reduction in peak intensity these metal oxides was observed due reduced crystallinity. absorption spectra, from UV–vis analysis, showed peaks at 354, 365, 525 nm NPs, respectively. An anticancer assay conducted human embryonic kidney (HEK 293) cervical carcinoma (HeLa) cell lines, while 1,1-diphenyl-2-picrylhydrazyl (DPPH) used antioxidant evaluation. higher potency with IC 50 2.15, 2.16, 3.18 µg/mL, respectively, than ascorbic acid (4.25 µg/mL). indicates that nanoparticles more effective capturing DPPH free radicals. Anticancer assays strong cytotoxic effects all nanoparticles, exhibiting highest activity (IC : 1.94 μM HEK 293 cells, 3.23 HeLa cells), surpassing NPs. Cell viability both cells decreased nanoparticle concentration increased, confirming dose-dependent cytotoxicity. green their composite potential biomedical applications.

Language: Английский

Citations

0

Comparative Performance and Emission Analysis of Soybean and Algae Biodiesels in Low Heat Rejection Engines DOI Creative Commons
Ratchagaraja Dhairiyasamy, Wasurat Bunpheng,

Chan Choon Kit

et al.

Energy Science & Engineering, Journal Year: 2025, Volume and Issue: unknown

Published: March 5, 2025

ABSTRACT The quest for sustainable energy solutions has driven extensive research into biodiesel derived from renewable sources such as soybean oil and algae. This study aims to optimize production algae using transesterification pyrolysis processes. Additionally, it evaluates the performance emission characteristics of these biodiesels in conventional low heat rejection (LHR) engines enhance understanding processes their impact on engine emissions. Soybean were used feedstocks via pyrolysis. produced biodiesels, specifically methyl ester (SBME), (ALME), pyrolytic (SBPO), tested both LHR engines. Performance metrics brake‐specific fuel consumption (BSFC), brake thermal efficiency (BTE), exhaust gas temperature (EGT), emissions (CO, HC, NOx) analyzed. SBME20 blend demonstrated superior with lower BSFC, higher BTE, reduced CO HC compared ALME20 SBPO20 blends. However, NOx due increased combustion temperatures. engine's enhanced environment improved efficiency, particularly SBME20, which exhibited best overall profile. concludes that is most efficient environmentally friendly engines, highlighting potential a viable feedstock production. Further optimization required achieve comparable levels.

Language: Английский

Citations

0

Green Synthesis: An Eco-Friendly Approach for the Synthesis of Silver Nanoparticles Functionalized with Operculina turpethum and It’s In vitro and in vivo Biological Activities DOI Creative Commons
Sami Bawazeer

International Journal of Nanomedicine, Journal Year: 2025, Volume and Issue: Volume 20, P. 2991 - 3005

Published: March 1, 2025

Introduction: Silver nanoparticles (AgNPs) have gained significant attention in biomedical applications. Green synthesis methods provide an eco-friendly and cost-effective approach to AgNPs production, utilizing plant extracts as reducing stabilizing agents. In this study, were synthesized using the methanolic extract of Operculina turpethum . Methodology: O. extract, their formation was confirmed through various analytical techniques. The antibacterial activity both crude assessed against Staphylococcus aureus. Enzyme inhibition studies conducted for urease, α-glucosidase, carbonic anhydrase II, xanthine oxidase. Analgesic sedative activities evaluated standard models. Results: exhibited zone 14 mm S. aureus , greater than (12 mm) but lower Linezolid (25 mm). revealed strong activity, particularly urease (96.09% inhibition, IC 5o = 25.65 ± 0.97 μg/mL). demonstrated superior analgesic effects (81.98% at 10 mg/kg), comparable diclofenac sodium (86.02%). Sedative dose-dependent, reaching 35.09% mg/kg. Discussion: enhanced suggests improved bioavailability interaction with bacterial membranes. enzyme inhibitory potential indicates possible therapeutic role enzyme-related disorders. pain management agents neuropharmacology. results demonstrate efficacy green-synthesized Conclusion: antibacterial, inhibitory, analgesic, properties suggest promising Further research should explore mechanisms vivo safety clinical Keywords: Ag NPs, studies, activities,

Language: Английский

Citations

0

Green Synthesis and Characterization of Copper Oxide Nanoparticles from Durian (Durio zibethinus) Husk for Environmental Applications DOI Open Access
Yanpeng Liang, Yu Bin Chan, Mohammod Aminuzzaman

et al.

Catalysts, Journal Year: 2025, Volume and Issue: 15(3), P. 275 - 275

Published: March 15, 2025

Landfill leachate, a complex wastewater generated from municipal solid waste (MSW) landfills, presents significant environmental challenges due to its high organic content and toxic pollutants. This study proposes sustainable solution by employing the green synthesis of copper oxide nanoparticles (CuO NPs) using durian (Durio zibethinus) husk extract, which serves as natural reducing stabilizing agent. approach transforms agricultural into valuable resource for remediation. The was carried out under mild conditions, avoiding harmful chemicals energy consumption. CuO NPs were characterized scanning electron microscopy (SEM), high-resolution transmission (HR-TEM), X-ray diffraction (XRD), energy-dispersive spectroscopy (EDX), Fourier-transform infrared (FTIR), UV-Vis examine their morphology, crystallinity, purity, optical properties. SEM HR-TEM analyses revealed mainly spherical with an average size 35–50 nm minimal aggregation. XRD analysis confirmed presence highly crystalline monoclinic phase CuO, while EDX spectrum showed distinct peaks corresponding (72%) oxygen (28%) weight, confirming purity material. Preliminary tests demonstrated photocatalytic efficiency NPs, achieving up 79% reduction in chemical demand (COD) landfill leachate. These findings underscore potential green-synthesized applications, offering innovative, method treatment supporting advancement management practices.

Language: Английский

Citations

0

Synthesis of a Novel Antibacterial Nanocomposite Based on Periodic Mesoporous Organosilica, Zinc Oxide, and Medical Leech Saliva as a Nanocarrier for Streptomycin Release DOI

Armin Amirsoleimani,

Zohreh Bahrami, Khatereh Kafshdouzan

et al.

Surfaces and Interfaces, Journal Year: 2025, Volume and Issue: unknown, P. 106445 - 106445

Published: April 1, 2025

Language: Английский

Citations

0

Review in green synthesis mechanisms, application, and future prospects for Garcinia mangostana L. (mangosteen)-derived nanoparticles DOI Creative Commons
Yu Bin Chan, Mohammod Aminuzzaman,

Xinn-Tze Chuah

et al.

Nanotechnology Reviews, Journal Year: 2025, Volume and Issue: 14(1)

Published: Jan. 1, 2025

Abstract The growing global demand for sustainable and cost-effective methods of nanomaterial production has driven the development green synthesis techniques, offering a safer alternative to traditional, hazardous approaches. Among numerous plants utilized this purpose, Garcinia mangostana L. (mangosteen) stands out due its high content bioactive phytochemicals, such as α-mangostin, xanthones, other secondary metabolites. These compounds serve natural reducing, capping, stabilizing agents in metal oxide nanoparticles (NPs) silver, gold, zinc oxide. In contrast traditional approaches reliant on toxic chemicals harsh circumstances, mangosteen extracts facilitate NPs moderate conditions, viable strategy nanotechnology. This review article offers thorough examination processes utilizing from mangosteen, going over physicochemical characteristics resultant their uses, antimicrobial anticancer properties, antioxidant therapy, environmental remediation. It is highlighted that synthesized have potential solve health issues. However, enable wider industrial commercial applications, important issues including scalability, repeatability NP long-term stability need be addressed. addition providing insights into creation NPs, study critically evaluates existing research lays groundwork future developments

Language: Английский

Citations

0

Kigelia pinnata fruit extract mediated green synthesis of Ce11O20/CeCu/CuO nanocomposites and their anticancer and antibacterial properties DOI
A. K. Gautam, Neelam Gupta,

Snigdha Dwivedi

et al.

Nano-Structures & Nano-Objects, Journal Year: 2024, Volume and Issue: 39, P. 101287 - 101287

Published: Aug. 14, 2024

Language: Английский

Citations

3

Sustainable synthesis of ZnO nanostructures using Ficus religiosa leaf extract with enhanced photocatalytic and antibacterial activity DOI

Noureen Ansari,

Md. Kavish,

Javed Ahmad Wagay

et al.

Materials Science and Engineering B, Journal Year: 2024, Volume and Issue: 310, P. 117752 - 117752

Published: Oct. 10, 2024

Language: Английский

Citations

3

Green synthesis of ZnO nanoparticles in Zinc chloride:Choline chloride deep eutectic solvent-characterization antibacterial and antioxidant agents DOI

A. Vijayakumar,

Ritty Mohan,

P. Jayaprakash

et al.

Journal of the Indian Chemical Society, Journal Year: 2024, Volume and Issue: unknown, P. 101375 - 101375

Published: Sept. 1, 2024

Language: Английский

Citations

2

Green Synthesis and Characterization of Apple Peel‐Derived Selenium Nanoparticles for Anti‐Fungal Activity and Effects of MexA Gene Expression on Efflux Pumps in Acinetobacter baumannii DOI
Mais E. Ahmed, Ghassan M. Sulaiman,

Buthenia A. Hasoon

et al.

Applied Organometallic Chemistry, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 8, 2024

ABSTRACT Selenium nanoparticles (Se‐NPs) were produced adopting an environmentally benign green synthetic approach from the waste biomaterial obtained apple peel extract (APE). The NPs characterized through UV–Visible spectroscopy (UV–Vis), atomic force microscopy (AFM), Fourier‐transform infrared (FT‐IR), X‐ray diffraction (XRD), field emission‐scanning electron (FE‐SEM), and transmission (TEM). spectra exhibited absorption peak λ max at 295 nm, confirming formation of Se‐NPs. AFM examination revealed roughness distribution nanoparticles, FT‐IR ascertained surface‐contained functional groups presence. XRD confirmed crystalline nature sample, FE‐SEM validated surface morphology size range 52 to 84 nm. TEM demonstrated spherical shapes Se‐NPs with a face‐centered cubic crystal nature, whereas analysis showed mean 70 minimum inhibitory concentration (MIC) 500 μg mL −1 against Candida spp ., namely, C. albicans , guilliermondii ciferrii their anti‐fungal activity in control minor statistical difference ( p < 0.05) dissemination zones inhibition for treatment these fungi. effects on MexA gene expression efflux pump role gene's down regulation treated fungal strains. multi‐drug resistant microbes.

Language: Английский

Citations

2