Indonesian Journal of Chemistry,
Journal Year:
2022,
Volume and Issue:
23(1), P. 148 - 148
Published: Oct. 6, 2022
The
aim
of
the
current
study
is
to
prepare
organomercury
and
organotellurium
compounds
containing
amino
groups
such
as
[1,1'-biphenyl]-4-amine
their
derivatives
by
a
mercuriation
reaction.
research
includes
preparation
new
compound
based
on
[1,1'-biphenyl]-4-amine.
C12H10NHgCl
(A)
was
obtained
reaction
mercuric
acetate
lithium
chloride.
C12H10Br3NTe
(B),
C24H20N2Br2Te
(C),
C24H20N2Te
(D),
C24H20N2Te2
(E)
were
prepared
different
reactions
get
corresponding
compounds.
All
ligands
characterized
using
infrared
spectroscopy
mass
spectroscopy.
DFT
has
been
basis
set
3-21G
investigate
molecular
structure
HOMO
LUMO
surfaces,
geometrical
structure,
energy
gap
have
throughout
geometry
optimization.
Finally,
electron
affinity,
electronegativity,
electrophilicity,
ionization
potential,
lower
case
calculated
discussed.
result
chemical
analysis
showed
that
it
agreed
with
proposed
structures,
theoretical
concluded
more
stability
Biomedicines,
Journal Year:
2023,
Volume and Issue:
11(10), P. 2698 - 2698
Published: Oct. 3, 2023
Heteroatom
steroids,
a
diverse
class
of
organic
compounds,
have
attracted
significant
attention
in
the
field
medicinal
chemistry
and
drug
discovery.
The
biological
profiles
heteroatom
steroids
are
considerable
interest
to
chemists,
biologists,
pharmacologists,
pharmaceutical
industry.
These
compounds
shown
promise
as
potential
therapeutic
agents
treatment
various
diseases,
such
cancer,
infectious
cardiovascular
disorders,
neurodegenerative
conditions.
Moreover,
incorporation
heteroatoms
has
led
development
targeted
delivery
systems,
prodrugs,
other
innovative
approaches.
represent
fascinating
area
research,
bridging
fields
chemistry,
pharmacology.
exploration
their
chemical
diversity
activities
holds
for
discovery
novel
candidates
more
effective
treatments.
Dalton Transactions,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 1, 2025
Organotellurium
ligand-facilitated
metal
structures
are
known
for
their
catalytic
activity,
anti-cancer
activities,
and
nanomaterial
applications.
A
wide
range
of
organotellurium
ligands,
including
telluroethers,
pincer-based
frameworks,
tellurolates,
have
been
extensively
explored
coordination
with
diverse
centers.
These
ligands
successfully
complexed
base
metals,
platinum
group
rare
earth
elements,
representative
providing
a
unified
resource
literature
on
complexes
ligands.
The
resulting
metal-organotellurium
exhibit
intriguing
structural
diversities
potential
applications
in
catalysis,
materials
science,
chemistry.
comprehensive
review
various
has
not
available
since
2005.
Moreover,
within
the
broader
field
chalcogen
chemistry,
remain
relatively
less
explored.
Hence,
this
focuses
synthetic
strategies
containing
addressing
significant
critical
gap
existing
literature.
This
provides
analysis
focusing
synthesis,
diversity,
Beyond
fundamental
significance,
these
play
vital
role
life
sciences,
nanochemistry,
science.
Their
proficiency
is
evident
essential
organic
reactions,
Suzuki-Miyaura
Mizoroki-Heck
couplings,
alcohol
oxidation,
C-N
bond
formation,
aldehyde
activation,
nitrophenol
reduction.
Molecules,
Journal Year:
2025,
Volume and Issue:
30(9), P. 2053 - 2053
Published: May 5, 2025
Given
the
crucial
roles
of
carbohydrates
in
energy
supply,
biochemical
processes,
signaling
events
and
pathogenesis
several
diseases,
development
carbohydrate
analogues,
called
glycomimetics,
is
a
key
research
area
Glycobiology,
Pharmacology,
Medicinal
Chemistry.
Among
many
structural
transformations
explored,
replacement
endo-
exocyclic
oxygen
atoms
by
carbon
(carbasugars)
or
heteroatoms,
such
as
nitrogen
(aza-
iminosugars),
phosphorous
(phosphasugars),
sulfur
(thiosugars),
selenium
(selenosugars)
tellurium
(tellurosugars)
have
garnered
significant
attention.
These
isosteric
substitutions
can
modulate
bioavailability,
stability,
bioactivity,
while
introducing
new
properties,
redox
activity,
interactions
with
pathological
lectins
enzymes,
cytotoxic
effects.
In
this
manuscript
we
focused
on
three
major
families
glycomimetics:
thio-,
seleno-,
tellurosugars.
We
provide
comprehensive
review
most
relevant
synthetic
pathways
leading
to
primarily
at
endocyclic
glycosidic
positions.
The
scope
includes
metal-catalyzed
reactions,
organocatalysis,
electro-
photochemical
transformations,
free-radical
automated
syntheses.
Additionally,
mechanistic
insights,
stereoselectivity,
biological
properties
are
also
discussed.
diversity
promising
bioactivities
these
glycomimetics
underscore
their
significance
area.
Organic Chemistry Frontiers,
Journal Year:
2022,
Volume and Issue:
9(19), P. 5225 - 5236
Published: Jan. 1, 2022
Herein
we
report
the
use
of
rongalite
in
PEG-400
as
a
general,
efficient,
and
environmentally
benign
reductive
system
for
synthesis
wide
range
2,5-disubstituted
chalcogenophenes
from
elemental
sulfur,
selenium
tellurium.
Reviews in Inorganic Chemistry,
Journal Year:
2021,
Volume and Issue:
41(3), P. 151 - 198
Published: Jan. 26, 2021
Abstract
Technetium
radionuclide
(
99m
Tc)
has
excellent
extent
of
disintegration
properties
and
occupies
a
special
place
in
the
field
nuclear
medicinal
chemistry
other
health
disciplines.
Current
review
describes
recent
approaches
synthesis
detailed
ways
for
radio-pharmaceuticals
technetium
which
have
been
developed
to
treat
diagnose
biotic
disorders.
These
labeled
established
apply
diagnostic
medicine
especially
imaging
different
body
parts
such
as
brain,
heart,
kidney,
bones
so
on,
through
single
photon
emission
computed
tomography
(SPECT)
that
is
thought
be
difficult
image
organs
by
using
common
X-ray
MRI
(Magnetic
Resonance
Imaging)
techniques.
This
highlights
accounts
an
inclusive
study
on
various
synthetic
routes
ligands
with
donor
atoms
carbon,
nitrogen,
sulphur,
phosphorus
etc.
compounds
can
utilized
next
generation
radio-pharmaceuticals.
Main Group Chemistry,
Journal Year:
2024,
Volume and Issue:
unknown, P. 1 - 8
Published: Jan. 9, 2024
The
synthesis
and
single
crystal
X-ray
studies
of
bis(trimethylsilylmethyl)
telluriumdiiodide
was
studied
through
an
insertion
route
with
quantitative
yield.
This
molecule
characterized
the
help
1H
NMR,
elemental
analysis
single-crystal
studies.
new
crystalline
provides
a
supramolecular
synthon
in
lattices
tellurium(IV)
diiodide
showing
2d
synthons
associated
C-H
-
I
interactions.
Anais da Academia Brasileira de Ciências,
Journal Year:
2024,
Volume and Issue:
96(1)
Published: Jan. 1, 2024
The
cognitive
deficit,
which
is
like
Alzheimer's
disease
and
associated
with
oxidative
damage,
may
be
induced
by
exposure
to
streptozotocin.
This
study
aimed
evaluate
if
the
tellurium-containing
organocompound,
3j,
5'-arylchalcogeno-3-aminothymidine
derivative,
interferes
effects
of
streptozotocin,
as
well
investigate
its
toxicity
in
adult
mice.
Cognitive
deficit
was
two
doses
streptozotocin
(2.25
mg/kg/day,
48
h
interval)
intracerebroventricularly.
After,
mice
were
subcutaneously
treated
3j
(8.62
mg/kg/day)
for
25
days.
assessed
evaluating
hippocampal
cortical
acetylcholinesterase
behavioral
tasks.
investigated
10
(0,
21.55,
or
43.10
37
4.31,
8.62
days
assessing
biometric
parameters
glucose
urea
levels,
alanine
aminotransferase
activity
blood
plasma.
did
not
alter
alterations
exposure.
On
other
hand,
normalized
hippocampus
activity,
enhanced
Toxicity
evaluation
showed
that
administration
either
cause
harmful
on
biochemical
analyzed.
Therefore,
does
present
any
apparent
reverts
increase
young
