Journal of Neuroscience, Journal Year: 2022, Volume and Issue: 42(47), P. 8755 - 8757
Published: Nov. 23, 2022
Over the past 40 years, central goal of cognitive neuroscience has been to interpret neural signals. To do so, it focuses on depicting commonalities between individuals at population level ([Raizada and Connolly, 2012][1]). However, everyone's perception world is shaped differently by
Language: Английский
Proceedings of the National Academy of Sciences, Journal Year: 2024, Volume and Issue: 121(32)
Published: July 30, 2024
The primary visual cortex (V1) in blindness is engaged a wide spectrum of tasks and sensory modalities, including audition, touch, language, memory. This widespread involvement raises questions regarding the constancy its role whether it might exhibit flexibility function over time, connecting to diverse network functions specific task demands. would suggest that reorganized V1 assumes like multiple-demand system regions. Alternatively, varying patterns plasticity blind may be attributed individual factors, with different individuals recruiting preferentially for functions. In support this, we recently showed functional connectivity (FC) varies greatly across individuals. But do these represent stable plasticity, or are they driven more by instantaneous changes, now inhabiting V1? Here, tested FC from time. We show two years, unique highly small sample repeatedly sampled congenitally Further, using multivoxel pattern analysis, demonstrate reorganization allow decoding participant identity. Together recent evidence substantial differences connectivity, this indicates there consistent blindness, which differ each individual. suggests variability could used seek neuromarkers sight rehabilitation assistive approaches.
Language: Английский
Citations
7
Published: Feb. 4, 2025
Research on brain plasticity, particularly in the context of deafness, consistently emphasizes reorganization auditory cortex. However, a critical question arises: to what extent do all individuals with deafness show same level reorganization? To address this question, we examined individual differences functional connectivity (FC), specifically from deprived Our findings demonstrate remarkable differentiation between deriving absence shared experiences, resulting heightened FC variability among deaf individuals, compared more consistent hearing group. Notably, language regions becomes diverse across deafness. This does not stem delayed acquisition, as it is found native signers, who are exposed rich natural since birth. comparing diversity signers and were early development, that experience also impacts differences, although moderate extent. Overall, our research points out intricate interplay plasticity shedding light ways manifests individuals. It further joins blindness, showing affected by sensory experience. Finally, these highlight importance considering personalized rehabilitation for loss.
Language: Английский
Citations
0
eLife, Journal Year: 2025, Volume and Issue: 13
Published: March 12, 2025
Research on brain plasticity, particularly in the context of deafness, consistently emphasizes reorganization auditory cortex. But to what extent do all individuals with deafness show same level reorganization? To address this question, we examined individual differences functional connectivity (FC) from deprived Our findings demonstrate remarkable differentiation between deriving absence shared experiences, resulting heightened FC variability among deaf individuals, compared more consistent hearing group. Notably, language regions becomes diverse across deafness. This does not stem delayed acquisition; it is found native signers, who are exposed natural since birth. However, comparing diversity signers and were early development, that experience also impacts differences, although a moderate extent. Overall, our research points out intricate interplay plasticity shedding light ways manifests individuals. It joins increased blindness highlights importance considering personalized rehabilitation for sensory loss.
Language: Английский
Citations
0
PLoS Biology, Journal Year: 2023, Volume and Issue: 21(7), P. e3001930 - e3001930
Published: July 25, 2023
We can sense an object’s shape by vision or touch. Previous studies suggested that the inferolateral occipitotemporal cortex (ILOTC) implements supramodal representations as it responds more to seeing touching objects than shapeless textures. However, such activation in anterior portion of ventral visual pathway could be due conceptual representation object imagery triggered object. addressed these possibilities directly comparing and early blind (who lack experience/imagery) sighted participants. found bilateral ILOTC both groups showed stronger during a verification task made on names same manmade objects. Moreover, distributed activity encoded similarity but not association among Besides ILOTC, we also groups’ premotor cortices intraparietal sulcus (IPS), frontoparietal circuit relating grasping haptic processing. In contrast, activated left perisylvian brain network language processing and, interestingly, cuneus participants only. The had functional connectivity network, forming modular structure specialized representation. Our results conclusively support selectively independently experience, this unique functionality likely comes from its privileged connection circuit.
Language: Английский
Citations
9
Journal of Cognitive Neuroscience, Journal Year: 2022, Volume and Issue: 35(2), P. 200 - 225
Published: Nov. 15, 2022
Abstract Resting-state fMRI studies have revealed that individuals exhibit stable, functionally meaningful divergences in large-scale network organization. The locations with strongest deviations (called “variants”) a characteristic spatial distribution, qualitative evidence from prior reports suggesting this distribution differs across hemispheres. Hemispheric asymmetries can inform us on constraints guiding the development of these idiosyncratic regions. Here, we used data Human Connectome Project to systematically investigate hemispheric differences variants. Variants were significantly larger right hemisphere, particularly along frontal operculum and medial cortex. left hemisphere appeared most commonly around TPJ. We investigated how variant vary by functional they compare typical distributions. For some networks, variants seemingly increase group-average (e.g., language is slightly bigger also more frequently hemisphere). other counter default mode but frequent Intriguingly, left- right-handers differed their for cingulo-opercular frontoparietal are connected lateralized traits. These findings demonstrate aspects brain organization differ discuss may developmental relate functions differentially linked two
Language: Английский
Citations
10
Neuropsychologia, Journal Year: 2023, Volume and Issue: 185, P. 108583 - 108583
Published: May 2, 2023
Sensory experience shapes brain structure and function, it is likely to influence the organisation of functional networks brain, including those involved in cognitive processing. Here we investigated early deafness on resting-state its relation executive We compared connectivity between deaf hearing individuals across 18 400 ROIs. Our results showed significant group differences seeds auditory network most large-scale particular somatomotor salience/ventral attention networks. When fMRI their link behavioural performance function tasks (working memory, inhibition switching), groups were found association such as default-mode These findings indicate that sensory influences not only networks, but also has a measurable impact supporting Overall, our suggest different developmental pathways can support processing adult brain.
Language: Английский
Citations
4
Cortex, Journal Year: 2024, Volume and Issue: 174, P. 241 - 255
Published: March 19, 2024
Language: Английский
Citations
1
Published: April 26, 2024
Research on brain plasticity, particularly in the context of deafness, consistently emphasizes reorganization auditory cortex. However, a critical question arises: to what extent do all individuals with deafness show same level reorganization? To address this question, we examined individual differences functional connectivity (FC), specifically from deprived Our findings demonstrate remarkable differentiation between deriving absence shared experiences, resulting heightened FC variability among deaf individuals, compared more consistent hearing group. Notably, increased is pronounced regions where diverges and reflecting how reorganizes response sensory deprivation. Additionally, language also becomes diverse across individuals. Importantly, does not stem delayed acquisition, as it found native signers, who are exposed rich natural since birth. Further, comparing diversity signers were early development, that experience impacts differences, although moderate extent. Overall, our research points out intricate interplay plasticity shedding light ways manifests It further joins blindness, showing affected by experience. Finally, these highlight importance considering personalized rehabilitation for loss.
Language: Английский
Citations
1
eLife, Journal Year: 2024, Volume and Issue: unknown
Published: April 26, 2024
Research on brain plasticity, particularly in the context of deafness, consistently emphasizes reorganization auditory cortex. However, a critical question arises: to what extent do all individuals with deafness show same level reorganization? To address this question, we examined individual differences functional connectivity (FC), specifically from deprived Our findings demonstrate remarkable differentiation between deriving absence shared experiences, resulting heightened FC variability among deaf individuals, compared more consistent hearing group. Notably, language regions becomes diverse across deafness. This does not stem delayed acquisition, as it is found native signers, who are exposed rich natural since birth. comparing diversity signers and were early development, that experience also impacts differences, although moderate extent. Overall, our research points out intricate interplay plasticity shedding light ways manifests individuals. It further joins blindness, showing affected by sensory experience. Finally, these highlight importance considering personalized rehabilitation for loss.
Language: Английский
Citations
1
Human Brain Mapping, Journal Year: 2024, Volume and Issue: 45(17)
Published: Nov. 22, 2024
ABSTRACT Human behavior can be remarkably shaped by experience, such as the removal of sensory input. Many studies conditions stroke, limb amputation, and vision loss have examined how input changes brain function. However, an important question yet to answered is: when is lost, does change its connectivity preferentially use some remaining inputs over others? In individuals with healthy vision, central portion retina used for everyday visual tasks, due ability discriminate fine details. When lost in like macular degeneration, peripheral must relied upon those portions receiving “preferential” usage others. Using resting‐state fMRI collected during total darkness, we deprivation preferential influence intrinsic functional cortex studying selective late stages degeneration. Specifically, between category‐selective areas cortical representation three retina: lesioned area, a region intact retina, non‐preferentially region. We found that regions representing spared regardless whether they are used, exhibit plasticity Cortical representations retinal locations showed stronger MT, involved processing motion. These results suggest long‐term produce widespread effects throughout early cortex, used. findings support idea connections maintain capacity well after critical periods development.
Language: Английский
Citations
1