Deleted Journal,
Journal Year:
2025,
Volume and Issue:
7(3)
Published: Feb. 24, 2025
Marine
actinomycetes
are
promising
sources
of
antibacterial
compounds
that
may
alleviate
antimicrobial
resistance.
This
study
aimed
to
evaluate
the
potential
marine
secondary
metabolites
against
staphylococci
and
characterize
their
mechanism
action.
The
were
obtained
from
Salt
Rock
Beach,
South
Africa
using
isolation
agar
medium
identified
by
16S
rRNA
sequencing.
Antibacterial
efficacy
was
evaluated
broth
microdilution
method.
effect
on
respiratory
chain
dehydrogenase
activity
membrane
integrity
analyzed
iodonitrotetrazolium
chloride
260
absorbing
materials
assays,
respectively.
Liquid
chromatography-mass
spectrometry
analysis
done
identify
chemical
constituents
bacterial
extract.
Streptomyces
SRST1SA2
only
isolate
whose
revealed
anti-Staphylococcus
activity.
extract
showed
minimum
inhibitory
concentration
(MIC)
bactericidal
(MBC)
values
ranging
0.25
1
mg/ml
0.5–1
mg/ml,
inhibited
growth
interfering
with
integrity.
LC–MS
spectrum
such
as
myristic
acid
(C14H28O2),
palmitic
(C16H32O2),
oleic
(C18H34O2).
sp.
has
serve
a
source
staphylococci.
Polymers,
Journal Year:
2025,
Volume and Issue:
17(5), P. 646 - 646
Published: Feb. 27, 2025
The
aim
of
this
study
was
to
develop
gelatin-based
films
incorporating
Melaleuca
alternifolia
essential
oil
(MEO)
and
assess
their
application
on
refrigerated
chicken
breasts.
results
showed
that
MEO
exhibited
antimicrobial
activity
against
Pseudomonas
aeruginosa
Salmonella
sp.,
with
inhibition
zones
17
mm
9
mm,
respectively.
minimum
inhibitory
concentration
(MIC)
10%
for
P.
15%
demonstrating
greater
efficacy
aeruginosa.
antioxidant
analysis
using
the
ABTS
method
revealed
1309
±
18.0
μM
Trolox/g,
while
FRAP
resulted
in
446
5.78
FeSO4/g.
characterization
by
gas
chromatography
identified
major
compounds,
including
2-carene,
γ-terpinene,
terpine-4-ol,
α-terpineol.
Incorporating
into
gelatin
structural
changes,
such
as
an
increase
thickness
(from
0.059
0.127
mm)
water
vapor
permeability.
Furthermore,
addition
conferred
homogeneous
properties
no
visible
cracks.
incorporation
has
shown
activity,
a
significant
higher
concentrations.
packaged
samples
retained
more
mass
than
control
group,
which
lost
about
90%
its
weight
during
storage.
Texture
only
8%
variation
Melaleuca-coated
compared
19.6%
group.
These
findings
indicate
containing
effectively
improve
shelf
life
Processes,
Journal Year:
2025,
Volume and Issue:
13(3), P. 850 - 850
Published: March 14, 2025
Frankincense
resin
(Boswellia
serrata),
native
to
arid
regions
of
India,
the
Middle
East,
and
parts
Africa,
has
been
highly
valued
for
its
medicinal
properties.
This
study
evaluated
antimicrobial
potential
methanolic
extracts
Boswellia
serrata
against
Staphylococcus
aureus,
Pseudomonas
aeruginosa,
Listeria
monocytogenes.
High-performance
thin-layer
chromatography
(HPTLC)
coupled
with
bioautography
identified
bioactive
zones,
while
Liquid
Chromatography–Mass
Spectrometry
(LC-MS)
quantified
phenolic
terpenoid
compounds.
The
cytotoxicity
was
assessed
on
HaCaT
human
keratinocyte
cells
evaluate
safety
dermatological
applications.
results
demonstrated
significant
antibacterial
activity,
particularly
S.
aureus
L.
bioautograms
revealed
that
samples
from
central
southern
Serbia
showed
highest
effect
tested
bacterial
strains.
active
compounds
included
11-keto-β-boswellic
acid
(up
3733.96
μg/g),
gallic
(110.93
naringenin
(53.13
μg/g).
Cytotoxicity
assays
confirmed
non-toxic
effects
at
10
µg/mL,
sample
6
enhancing
viability
by
137%,
higher
concentrations
(50
µg/mL)
variable
cytotoxicity.
These
findings
highlight
B.
as
a
natural
agent,
antibiotic-resistant
pathogens.
Its
therapeutic
applicability
in
pharmaceutical
cosmetic
formulations
is
promising
provided
dosing
ensures
balance
between
efficacy
safety.
Environmental Science and Ecotechnology,
Journal Year:
2025,
Volume and Issue:
unknown, P. 100557 - 100557
Published: March 1, 2025
The
widespread
and
indiscriminate
use
of
biocides
poses
significant
threats
to
global
health,
socioeconomic
development,
environmental
sustainability
by
accelerating
antibiotic
resistance.
Bacterial
resistance
development
is
highly
complex
influenced
significantly
factors.
Increased
biocide
usage
in
households,
agriculture,
livestock
farming,
industrial
settings,
hospitals
produces
persistent
chemical
residues
that
pollute
soil
aquatic
environments.
Such
contaminants
contribute
the
selection
proliferation
resistant
bacteria
antimicrobial
genes
(ARGs),
facilitating
their
dissemination
among
humans,
animals,
ecosystems.
In
this
review,
we
conduct
a
critical
assessment
four
issues
pertaining
topic.
Specifically,
(i)
role
exerting
selective
pressure
within
resistome,
thereby
promoting
microbial
populations
contributing
spread
(ARGs);
(ii)
triggering
transient
phenotypic
adaptations
bacteria,
including
efflux
pump
overexpression,
membrane
alterations,
reduced
porin
expression,
which
often
result
cross-resistance
multiple
antibiotics;
(iii)
capacity
disrupt
make
genetic
content
accessible,
releasing
DNA
into
environment
remains
intact
under
certain
conditions,
horizontal
gene
transfer
determinants;
(iv)
bacterial
cells,
enhancing
interactions
between
biofilms
environment,
strengthening
biofilm
cohesion,
inducing
mechanisms,
creating
reservoirs
for
microorganisms
ARG
dissemination.
Collectively,
review
highlights
public
health
implications
use,
emphasizing
an
urgent
need
strategic
interventions
mitigate
proliferation.
