Preparation, physical, optical, ESR and γ-ray attenuation efficacy investigation of copper oxide/silver borosilicate glass

Scientific Reports, Journal Year: 2024, Volume and Issue: 14(1)

Published: Oct. 25, 2024

The sonication method was used to prepare a new set of CuO and CuO/Ag nanocomposites. particle size estimated using XRD HR-TEM while the morphology nanoparticles investigated with SEM. average sizes Ag falls in 29.32-35.80 nm 35.13-45.95 ranges, respectively. declared that has space groups C 1 c (9) 2/c (15), silver group F m -3 (225). XPS analysis indicated presence as

Language: Английский

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Mesoporous silica micro/nanomotors: A new horizon in biomedical applications and precision medicine

Applied Materials Today, Journal Year: 2025, Volume and Issue: 43, P. 102673 - 102673

Published: March 13, 2025

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New binary and ternary SiO2 composites with Fe2O3 and Co2.74O4 and the evaluation of their γ-radiation shielding properties

Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)

Published: April 21, 2025

Abstract A new series of binary and ternary nanocomposites contains cobalt oxide or iron/cobalt oxides were manufactured to increase silicon dioxide $$\gamma$$ shielding power. XRD indicated the presence Co as 2.74 O 4 (COD: 1528446) iron Fe 3 9002318 9005814). Using Profex, Rietveld refinements carried out. The R w , ex x 2 G 4.49, 4.34, 1.07, 1.03, respectively, indicating good refinement parameters. XPS Si ( $$\hbox {Si}^{4+}$$ ), (Fe $$_{2}$$ $$_{3}$$ ) {Co}^{2+}$$ {Co}^{3+}$$ ). TEM analysis showed that all metal oxide@SBA-15 solids have characteristic well-organized SBA-15 structures. -radiation for prepared samples investigated via Monte-Carlo code (MCN) Phy-X software. results confirmed that, adding high concentrations cobalt-oxide hematite increases linear attenuation significantly. SiCoFe-3 sample, which highest content hematite, has best capability among synthesized SiCo/SiCoFe samples.

Language: Английский

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Unveiling the potency of ZnO and CuO nanocomposites in combating hepatocellular carcinoma by inducing cell death and suppressing migration

Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)

Published: May 3, 2025

Abstract Human hepatocellular carcinoma (HCC) is recognized as one of the leading causes death globally and resistant to several anticancer drugs. As a result, it critical identify more effective druggable therapies. Metal oxide nanoparticles (MO-NPs), especially nanocomposites, have recently received much attention owing their potential applications in cancer therapy. In this study, we synthesized zinc (ZnO) copper (CuO) nanocomposites different ratios (N1, N2, N3). We evaluated cytotoxicity against two HCC cell lines (HepG2 HuH-7) normal liver (BNL), compared with Sorafenib standard Then, investigated underlying mechanisms action employing flow cytometry, migration assay, western blot. The results showed that nanocomposite an equal ratio both ZnO CuO-NPs (N1) exhibited highest cytotoxic activity on HuH7 line while exerting no detrimental impact rat epithelial cells. Further investigation into toxicity N1 revealed three modalities induced (apoptotic, necrotic, autophagic) along S- G2/M cycle arrest, suggesting mitotic catastrophe. Furthermore, displayed potent anti-migratory activity, surpassing sorafenib, upregulated protein level autophagy marker beclin-1, downregulated EMT-marker vimentin. Overall, our findings combining ZnO-NPs intriguing combating HCC, providing prospective guidance for evolving therapy bimetallic NPs.

Language: Английский

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Structural, physical and optical properties of Bi4.86La1.14O9/PVA thin-film for shielding applications

Surfaces and Interfaces, Journal Year: 2025, Volume and Issue: unknown, P. 106567 - 106567

Published: May 1, 2025

Language: Английский

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