Medication adherence in patients with heart failure: a pilot observational study in outpatient practice DOI Creative Commons
В. Н. Ларина,

K. A. Zamyatin,

Ch. G. Gudiev

et al.

Russian Journal of Cardiology, Journal Year: 2024, Volume and Issue: 29(12S), P. 6180 - 6180

Published: Nov. 13, 2024

Aim. To assess clinical characteristics and medication adherence in patients with heart failure (HF) different left ventricle ejection fractions (LVEF). Material methods. The study involved 65 outpatients aged ≥60 years a verified diagnosis of HF. A standard physical examination, laboratory echocardiographic studies were performed. Adherence to treatment was assessed using the National Society Evidence-B ased Pharmacotherapy Scale. patient considered have complete score 0, incomplete — ≥1. Results. Preserved LVEF (≥50%) present 33 (50,8%) (mean age, 76,2±6,6 years). Mildly reduced (<50%) recorded 32 (49,2%) 69,8±7,7 years. Regardless LVEF, all (100%) had two or more chronic diseases, while 45,5% ≥50% 53,1% <50% took six medications. Most beta-blockers (78,8% group ≥50%; 87,5% <50%), isolated cases angiotensin receptor- neprilysin inhibitors (3% preserved LVEF; 6,3% moderately LVEF). At same time, no HF quadruple therapy. Full found 57,6% ≥50%, p=0,007. As leading reason for noncomplete treatment, most (61,1%) indicated forgetfulness. Conclusion. Complete rate EF is lower than mildly EF. require measures improve

Language: Английский

THE ROLE OF MATRIX METALLOPROTEINASE-9 AS A BIOLOGICAL MARKER IN HEART FAILURE DOI

Albina B. Sultangalieva,

Amina M. Alieva,

Alik M. Rakhaev

et al.

Russian Medicine, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 21, 2025

Heart failure (HF) is an important medical, social and economic problem. The study of new biological markers deepens our understanding the pathogenesis this disease. In modern cardiology, there a growing interest in matrix metalloproteinases (MMPs). These enzymes play role tissue remodeling, angiogenesis, as well cell proliferation, migration differentiation. purpose literature review to analyze current experimental clinical data on MMP-9 diagnostic prognostic marker HF. This presents analysis publications given topic. We conducted sources covering all materials 01.11.2024. Experimental studies have established that key participant cardiac since it directly involved degradation extracellular proteins activation profibrotic pathways, cytokines chemokines. Clinical trial indicate significant importance for diagnosis prognosis patients with

Language: Английский

Citations

0
Medication adherence in patients with heart failure: a pilot observational study in outpatient practice DOI Creative Commons
В. Н. Ларина,

K. A. Zamyatin,

Ch. G. Gudiev

et al.

Russian Journal of Cardiology, Journal Year: 2024, Volume and Issue: 29(12S), P. 6180 - 6180

Published: Nov. 13, 2024

Aim. To assess clinical characteristics and medication adherence in patients with heart failure (HF) different left ventricle ejection fractions (LVEF). Material methods. The study involved 65 outpatients aged ≥60 years a verified diagnosis of HF. A standard physical examination, laboratory echocardiographic studies were performed. Adherence to treatment was assessed using the National Society Evidence-B ased Pharmacotherapy Scale. patient considered have complete score 0, incomplete — ≥1. Results. Preserved LVEF (≥50%) present 33 (50,8%) (mean age, 76,2±6,6 years). Mildly reduced (<50%) recorded 32 (49,2%) 69,8±7,7 years. Regardless LVEF, all (100%) had two or more chronic diseases, while 45,5% ≥50% 53,1% <50% took six medications. Most beta-blockers (78,8% group ≥50%; 87,5% <50%), isolated cases angiotensin receptor- neprilysin inhibitors (3% preserved LVEF; 6,3% moderately LVEF). At same time, no HF quadruple therapy. Full found 57,6% ≥50%, p=0,007. As leading reason for noncomplete treatment, most (61,1%) indicated forgetfulness. Conclusion. Complete rate EF is lower than mildly EF. require measures improve

Language: Английский

Citations

0