Cardiac Arrhythmias and Conduction Disorders in Geriatric Patients with Cardiovascular Comorbidity

Published: March 21, 2025

Introduction. The polymorbidity characteristic of geriatric patients exerts a complex impact on the regulatory mechanisms cardiac function, significantly increasing likelihood arrhythmias and conduction disturbances when compared to younger age groups. aim this study is examine frequency disorders in with comorbid cardiovascular pathology order identify gender-specific features. Materials methods. A retrospective analysis was conducted 50 medical histories from cardiology department Republican Clinical Hospital No. 4 Saransk 2024. inclusion criteria for were elderly aged 75 89 years, diagnosed heart, presence pathology. comparative within group performed considering gender as variable.Results. predominant type arrhythmia 80% atrial fibrillation (with male predominance 1.5 times), characterized by persistent form (in 62.5% cases). supraventricular ventricular extrasystoles 28% (without significant differences), while Wolff – Parkinson White syndrome observed 8% cases (equally distributedbetween men women), flutter threefold predominance). Supraventricular paroxysmal tachycardia found 2% men). Conduction identified 34% patients, 1.8 times. most common finding first-degree atrioventricular block (AV block), present 47.1% all cases. More severe forms AV (second- third-degree) 17.6% left bundle branch 35.3%, twofold predominance. Post-infarction cardiomyosclerosis times more frequently men. Chronic heart failure reduced ejection fraction twice often men, functional classes 2–4. Arterial hypertension acute cerebrovascular accidents history whereas 2 diabetes obesity women. Strong positive correlations established between rhythm both sexes arterial hypertension, chronic failure, ischemic disease.Discussion conclusion. development their complications driven concomitant diseases. Comorbidity increases risk. Identified differences morbidity rates among highlight necessity addressing modifiable risk factors conducting thorough monitoring planning treatment strategies. This approach crucial achieving target blood pressure levels, modulating activity, managing associated conditions.

Language: Английский

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Features of central aortic pressure at patients with arterial hypertension aged 80 years and older, taking into account the presence of chronic heart failure and senile asthenia syndrome

Medical Herald of the South of Russia, Journal Year: 2025, Volume and Issue: 16(1), P. 28 - 38

Published: Feb. 10, 2025

Objective: to evaluate the parameters of central aortic pressure in patients with arterial hypertension (AH) depending on presence chronic heart failure (CHF) and senile asthenia syndrome (SSA). Materials methods: 320 AH were divided into four groups: group 1A — AH, SSA CHF (n=84), 1B without 2A (n=77), 2B (n=75). Central determined using a BPLab ABPM device Vasotens technology (“Petr Telegin”, Nizhny Novgorod). To process obtained data, statistical programs STATISTICA 12.0, SPSS 21.0, MedCalc 9.3.5.0 used. Results: SSA, higher average daily values SBP ao recorded compared both (p=0.004) (p=0.019). The led AIx hypertension, (p<0.001), (p<0.001). In CHF, regardless rates PBP ED (p<0.001) lower SERV recorded. When assessing degree influence or it was shown that had more pronounced effect indicators than SSA. Conclusion: aged 80 years older, development and, greater extent, accompanied by an increase pressure. With combination most disturbances elastic properties blood vessels observed, which is associated high cardiovascular risk.

Language: Английский

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Possibilities of Optimizing Drug Therapy for Myocardial Infarction: a Consensus on the Use of Type 2 Sodium-Glucose Co-Transporter Inhibitors. Conciliation Document of the Expert Group

Kardiologiia, Journal Year: 2025, Volume and Issue: 65(3), P. 35 - 47

Published: March 31, 2025

Ischemic heart disease, including previous myocardial infarction (MI), is one of the main causes for development and progression failure (HF). The presence HF before MI or in setting acute coronary catastrophe an extremely unfavorable prognostic factor leading to a multiple increase risk death rehospitalization due post-infarction period. In 2024, results two randomized clinical trials (RCTs) (DAPA-MI EMPACT-MI) were published, which assessed effect sodium-glucose co-transporter type 2 inhibitors (SGLT2i) on outcomes patients with MI. both studies, predetermined primary composite endpoint was not achieved. At same time, it shown that SGLT2i significantly reduced hospitalization (empagliflozin) contributed improvement metabolic (dapagliflozin). Also, safety early initiation period demonstrated. Based available observational working group has substantiated need implementing these RCT into practice proposed algorithm administering SGLT2 Thus, compelling anamnestic criteria diagnosis previously diagnosed diabetes mellitus, and/or chronic kidney HF, continuation timely during index recommended improve cardiovascular renal outcomes. RCTs taking account individual factors discharge may be considered order reduce HF.

Language: Английский

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Diagnosis statement in the case of "decapitated hypertension": opinion on the issue

Russian Journal of Cardiology, Journal Year: 2025, Volume and Issue: 30(2), P. 6234 - 6234

Published: March 14, 2025

The article discusses the statement of diagnosis hypertension (HTN) with severe left ventricular systolic dysfunction and resulting decrease in blood pressure (BP) to target levels or hypotension ("decapitated hypertension"). current Russian guidelines on HTN adults heart failure (HF) do not consider this situation. used classifications by its degree untreated patients achievement BP level antihypertensive therapy cannot correctly reflect situation case, since as such no longer exists, but a chronic disease continues exist. authors propose expand existing classification introducing term "history HTN", which reflects discussed period disease, allows be included diagnosis, substantiates unacceptability using period, well difficulties prescribing maximum doses HF medications.

Language: Английский

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Correction of anemia using an iron supplement with a hepcidin-independent absorption mechanism in patients with chronic heart failure with preserved left ventricular ejection fraction

Rational Pharmacotherapy in Cardiology, Journal Year: 2025, Volume and Issue: 21(1), P. 33 - 38

Published: March 3, 2025

Aim. To characterize anaemia in chronic heart failure (CHF) with preserved left ventricular ejection fraction (CHFpEF) and evaluate the effectiveness of an iron supplement a hepcidin- independent absorption mechanism. Material methods. An uncontrolled study included 30 patients CHFpEF NYHA class I-III anaemia. Patients received "standard therapy" for CHF combination sucrosomial (60 mg/day orally) three months. Treatment response was assessed via clinical blood test, metabolism parameters, inflammatory markers, functional tests at baseline months post-treatment. Results. Anaemia corresponds to disease elevated hepcidin content, 219 (149-553) ng/mL occurs impaired development deficiency. Hemoglobin levelincreased from 115 (98-117) g/L 120 (103-133) g/L, p = 0.01, red cell count increased 3.6 (3.5-4.1) × 1012/L 4 (3.7-5.3) 1012/L, 0.05, serum ferritin 106 (40-181) μg/L 117 (83-166) μg/L, 0.04. N-terminal natriuretic propeptide (NT-proBNP) level decreased 374 (330-443) 236 (128-349) ng/mL, 0.004. After treatment, exercise tolerance improved: 6-minute walk test distance 343.1 ± 100 m 397±73 (p 0.01). Quality life (QoL) determined by status assessment scale (CAS), 0.01 Minnesota Health Failure Questionnaire (MHFLQ), 0.002. Conclusion. Adding oral standard HFpEF therapy significantly hemoglobin levels, tolerance, QoL scores while reducing NT-proBNP levels after

Language: Английский

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Outpatient follow-up of patients with chronic heart failure by a general practitioner in primary health care. Guidelines

Published: April 12, 2025

Outpatient follow-up in primary care is one of the resources for reducing mortality from diseases circulatory system and increasing life expectancy. These guidelines contain a description current issues related to organization outpatient patients with chronic heart failure by general practitioner.The are intended district internists, practitioners (family doctors), internists shop medical district, as well secondary personnel working these doctors, paramedics paramedic-obstetric stations (paramedic health centers) case they assigned functions attending physician.The can be used public physicians, heads facilities their divisions.

Language: Английский

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Aspects of primary and secondary prevention of heart failure in patients with asthma

Published: April 10, 2025

The modern concept of a personalized approach to studying the relationship between diseases contributes an in-depth multimorbidity study. Asthma is one most common pathologies among chronic respiratory diseases, characterized by wide heterogeneity and high comorbidity, especially with cardiovascular in older age group. Due difficulties differential diagnosis these their mutually aggravated course, measures for prevention heart failure (HF) asthma patients should be structured.The aim review was highlight etiology, similarity clinical performance pathogenesis links HF asthma, as well main approaches asthma.The summarizes recommendations outpatient follow-up timely HF.

Language: Английский

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Developing the system of quality measures for medical care assessment in patients with chronic heart failure: methodology and criteria (review)

Saratov Journal of Medical Scientific Research, Journal Year: 2024, Volume and Issue: 20(4), P. 425 - 435

Published: Dec. 31, 2024

Objective: To develop a system of quality measures for monitoring the process and outcome medical care in patients with chronic heart failure (CHF) real clinical practice. Review methodology. The procedure selecting indicators to monitor treatment cardiological proposed by О M. Posnenkova (2013) was applied. An analysis Russian Ministry Health's guidelines on CHF (2024) conducted determine characteristics planned outcomes key proven impact outcomes. A systematic literature review using PRISMA methodology performed identify therapeutic interventions that achievement results real-world PubMed eLibrary databases were used. search depth from 2020 2024. Twenty-five sources selected. Conclusion. In practice it is advisable assess: 1) proportion HF reduced ejection fraction (EF) who have been prescribed quad-riple therapy (angiotensin-converting enzyme inhibitor/angiotensin receptor/angiotensin receptor neprilysin inhibitors + beta-blockers aldosterone antagonists sodium/glucose cotransporter 2 inhibitors); 2) preserved EF mildly inhibitors; 3) without adverse events (hospitalizations due or death) over past 12 months.

Language: Английский

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