Remote outcomes in patients with cardiovascular diseases in outpatient practice: data from a 10-year follow-up within the RECVAZA registry

CARDIOVASCULAR THERAPY AND PREVENTION, Journal Year: 2025, Volume and Issue: 23(12), P. 4269 - 4269

Published: Feb. 13, 2025

Aim. To evaluate outcomes over 10-year follow-up and risks of adverse events in patients with cardiovascular disease (CVD) within the outpatient registry. Material methods . In RECVAZA registry based on 3 Ryazan clinics, 3690 CVD (age, 66,1±12,9 years; men, 28,0%) were observed. For 2012-2023 (follow-up, 8,2±3,3 years), following assessed: death, myocardial infarction (MI), stroke, hospitalization for CVD. Information was obtained from medical records, surveys, electronic databases. Results. Over 10 years, 1595 (43,2%) died, 51% whom died 12% cancer. The highest proportion deaths among prior stroke (69,7%) MI (61,5%) before inclusion registry, a combination hypertension (HTN), coronary artery (CAD), heart failure (HF), atrial fibrillation (AF) — 79%, age ≥80 years 85,9%. all-cause death risk associated (hazard ratio (HR))=1,06 HR=1,07; p<0,001); male sex (HR=1,70 HR=1,62; (HR=1,86 HR=2,13; type 2 diabetes (HR=1,55 HR=1,67; low hemoglobin level (HR=1,66 HR=1,72; smoking (HR=1,51; p=0,001 p=0,003), respectively. to greatest extent (HR=1,77 HR=2,61; p<0,001), while AF (HR=1,65 3,78; p<0,001) systolic blood pressure <110 mm Hg (HR=2,72; p=0,01). Hospitalization no more than once per lower (1,9 times), higher frequency (1,6 times). Conclusion. follow-up, 43,2% died. rate history MI, diabetes, HTN, CAD, HF AF, levels. prognostically favorable, but it an increased death.

Language: Английский

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Risk factors and prevention of cardiovascular complications in breast cancer

CARDIOVASCULAR THERAPY AND PREVENTION, Journal Year: 2025, Volume and Issue: 23(12), P. 4194 - 4194

Published: Feb. 13, 2025

Breast cancer (BC) is the most common malignant tumor in women. In patients who have undergone antitumor treatment at an early stage of BC, death long term more often occurs from cardiovascular diseases (CVD) than cancer. Numerous studies indicate that risk cardiomyopathy and/or heart failure, coronary artery disease among BC survivors received anthracyclines trastuzumab increased. Currently, detection cardiotoxicity using cardiac imaging and circulating biomarkers widely evaluated clinical trials. At same time, high CVDs observed cured breast a consequence both adverse effects anticancer therapy on system, including antiestrogens, presence CVD factors. Large trials reported higher rates hypertension, hypercholesterolemia, ischemic postmenopausal receiving aromatase inhibitors. Strategies for prevention left ventricular dysfunction or failure such should include comprehensive evaluation individual assessment.

Language: Английский

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Associations of subclinical atherosclerosis with somatic diseases

Russian Journal of Preventive Medicine, Journal Year: 2025, Volume and Issue: 28(2), P. 109 - 109

Published: Feb. 27, 2025

Subclinical sclerosis is detected in about 50% of adult people (30 to 70% depending on localization). frequency the same with low cardiovascular risk, thus limiting feasibility integral prognostic scales. The subclinical comorbidity other somatic diseases plays an important role development complications and can serve as additional indicator for extended examination. that often accompany atherosclerosis include metabolic syndrome, progestogen-induced diabetes mellitus, fatty liver disease, psoriasis, antiphospholipid arthritis, systemic lupus erythematosus. associated disorders, including those a transient nature, inflammatory disease connective tissue skin, are closely related atherosclerosis. These peculiarities shall be considered when developing complex measures prevent comorbid conditions.

Language: Английский

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Outpatient follow-up of patients with chronic heart failure by a general practitioner in primary health care. Guidelines

Published: April 12, 2025

Outpatient follow-up in primary care is one of the resources for reducing mortality from diseases circulatory system and increasing life expectancy. These guidelines contain a description current issues related to organization outpatient patients with chronic heart failure by general practitioner.The are intended district internists, practitioners (family doctors), internists shop medical district, as well secondary personnel working these doctors, paramedics paramedic-obstetric stations (paramedic health centers) case they assigned functions attending physician.The can be used public physicians, heads facilities their divisions.

Language: Английский

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Chronic coronary artery disease: aspects of recording and coding in clinical practice (results of a survey of physicians)

CARDIOVASCULAR THERAPY AND PREVENTION, Journal Year: 2024, Volume and Issue: 23(5), P. 4027 - 4027

Published: May 29, 2024

Aim. To study the opinion of doctors about applicability, frequency and criteria for practical use codes International Classification Diseases, 10th revision (ICD-10) from group chronic coronary artery disease (CAD) — I25.0, I25.1, I25.8, I25.9. Material methods. This cross-sectional was conducted in period February 27, 2024 to March 11, on a continuous sample medical workers who agreed participate an anonymous survey as respondents. The questionnaire consisted introductory, personal main part, which 19 questions devoted various aspects CAD coding at doctor’s appointment during preparing death certificate. article presents results cardiologists (group 1) internists/general practitioners/family physicians 2). χ 2 test used compare two groups. Friedman hypothesis that physicians' different random. Kendall assess agreement between physicians. Calculations were carried out using Microsoft Office Excel 2021 SPSS-26.0. Results. A total 883 47 constituent entities Russian Federation took part survey. Half respondents believed there are differences I25.9 they necessary statistical recording. Although (59,2%) less likely than (65,9%) believe one or more 4 analyzed could be only basis risk factors, did not reach significance (p=0,1). need confirm paraclinical research methods varied 57,3% code 83,1% I25.1. In case patient CAD, almost third do see specified codes, but ready them clinical setting. addition, 14,6% responded when filling certificates would any codes. There is no among regarding practice (Kendall's coefficient concordance 0,084; p<0,001) cause (0,148; p<0,001). Conclusion. unified stance rules applicability least (I25.0, I25.9). correctly morbidity mortality rates individual forms ACAD based ICD-10 guidelines should include description consideration all most significant scenarios developed.

Language: Английский

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Therapeutic Aspects of Lipofilling, Abdominoplasty in Combination with Body Liposuction and Bariatric Surgery

Bulletin of Science and Practice, Journal Year: 2024, Volume and Issue: 10(7), P. 188 - 228

Published: July 14, 2024

This review article is dedicated to the therapeutic aspects of various plastic surgery procedures. Nowadays, improving appearance and quality life through becoming increasingly popular. Managing patients after lipofilling abdominoplasty combined with liposuction an interdisciplinary challenge. Intraoperative risks in are associated anesthesia comorbidities. The immediate response cardiovascular respiratory systems administration anesthetic agents anesthesiologist's qualifications determines success operations. duration surgery, volumetric disturbances, reduction body surface area, changes metabolic immunological status mechanical impact on adipose tissue significantly alter rate compensatory-adaptive reactions body. In long-term period lipofilling, abdominoplasty, liposuction, augmentation mammoplasty, systemic complications often observed. These include insomnia, chronic kidney disease, protein-energy malnutrition, arthropathies, nonspecific interstitial lung lesions, unverified hepatitis, lupus-like syndrome, antibodies transplanted fats silicone materials, idiopathic limb edema, as well autoinflammatory syndromes. presented work also provides data propofol infusion syndrome clinical-prognostic significance vascular endothelial growth factor surgery. authors’ team presents their own clinical obesity diseases. To maintain aesthetic effect prevent blepharoplasty, rhinoplasty, it recommended follow a hypoallergenic low-calorie diet for next 3-6 months, avoid night work, excessive physical exertion, simultaneous intake antibiotics anti-inflammatory drugs, sun exposure, trips mountainous areas, long flights.

Language: Английский

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Resolution of advisory board on issues in the diagnosis of asthma and COPD: current challenges and modern approaches to their resolution

Terapevticheskii arkhiv, Journal Year: 2024, Volume and Issue: 96(8), P. 846 - 851

Published: Sept. 14, 2024

Diagnosis of asthma and chronic obstructive pulmonary disease (COPD) remains an actual problem in Russia. The lack diagnostics control these diseases leads to serious consequences for public health economic damage. Effective initiatives improve the level diagnosis COPD include organization educational activities, instrumental methods examination, use mobile offices outreach work remote communities introduction medical information systems. digital technologies into practice will help quality care, increase efficiency centers, ensure timely respiratory diseases. modern approaches COPD, active validated questionnaires systems life patients reduce risks complications exacerbations

Language: Английский

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Cardio-oncology: a cardiologist's view on the problem of endovascular treatment of patients with coronary artery disease and severe aortic valve stenosis combined with cancer: a literature review

CARDIOVASCULAR THERAPY AND PREVENTION, Journal Year: 2024, Volume and Issue: 23(9), P. 4051 - 4051

Published: Oct. 24, 2024

Cardio-oncology is a new medical direction which responsible for the prevention of development, diagnosis and treatment cardiovascular disease (CVD) in patients with cancer. The prevalence cardiac pathology cancer turned out to be unexpectedly high, while only half two systems are referred cardiologist consultation receive optimal therapy. coincidence risk fa­ctors CVD suggests that these diseases have common underlying biological molecular mechanisms. Antitumor therapy radiation can also contribute onset progression CVD. Diagnosis coronary artery (CAD) difficult, since this group often lacks typical angina pain, most complaint dyspnea. Endovascular surgery CAD severe aortic valve stenosis an effective safe method treating concomitant However, given heterogeneity fact were not included randomized trials studying treatment, further research required area. Aim. To analyze literature on etiopathogenesis patients, as well clinical features potential innovative endovascular technologies. Conclusion. For management such comorbid participation multidisciplinary team personalized approach each patient necessary.

Language: Английский

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Comorbidity problems in patients with osteoporosis

HERALD of North-Western State Medical University named after I I Mechnikov, Journal Year: 2024, Volume and Issue: 16(3), P. 87 - 98

Published: Nov. 6, 2024

BACKGROUND: Osteoporosis is a metabolic skeletal disease characterized by decreased bone mass, impaired microarchitecture of tissue and, as consequence, fractures with minimal trauma. The social significance osteoporosis determined its consequences — the vertebral bodies and bones peripheral skeleton, leading to high medical costs causing level disability, including disability mortality. most often combined cardiovascular diseases caused atherosclerosis, which are widespread cause A small number studies have been devoted study features clinical manifestations in combination coronary heart osteoporosis. AIM: To identify frequency severity comorbid their risk factors postmenopausal MATERIALS AND METHODS: retrospective prospective cohort was conducted from 2013 2023. 8250 women were examined data records these patients who applied Center North-Western State Medical University named after I.I. Mechnikov Ministry Health Russian Federation 2020 analyzed. At stage, two comparison groups 100 without formed 500 (coronary disease, hypertension, type 2 diabetes, stroke, transient ischemic attack). Bone mineral density assessed based on Hologic Discoveri Wi dual-energy X-ray absorptiometry at points lumbar spine (L1–L4) femoral neck. Along traditional laboratory examination methods, metabolism markers (total calcium, phosphorus, vitamin D, urine analysis for deoxypyridinoline, C-terminal telopeptide 1 collagen, osteocalcin, alkaline phosphatase, parathyroid hormone) dynamically. In all patients, along general examination, an assessment performed. RESULTS: Body mass index higher group 28.4 (26.9–32.4) kg/m2 (p 0.001), versus 27.64 (25.8–30.0) 0.05). statistically lower than osteoporosis, amounted 37 (95% confidence interval 15.0–38.50) %, p control 9.55 7.67–15.0) % 0.001) according FRAX questionnaire Federation. Charlson values 5.1 4.7–5.6) points. As result correlation analysis, reliable positive relationship revealed between low L1–L4 hip metabolism: urinary deoxypyridinoline. We found negative index, absolute ten-year fracture duration early menopause, hypertension. assess dependence QRISK3-2018 multiple linear regression This model significant dependent variable tightness. coefficient determination 0.608, indicating 60.8% contribution taken into account variance QRISK3-2018. CONCLUSIONS: pathology more common, aggravating course disease. Knowledge prevalence concomitant joint will make it possible simultaneously form increased development, ensure prevention both same non-medical means drugs.

Language: Английский

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The main misconceptions in cardiology concerning obesity

Rational Pharmacotherapy in Cardiology, Journal Year: 2024, Volume and Issue: 20(5), P. 574 - 580

Published: Dec. 2, 2024

This article reviews common myths and stereotypes about obesity that distort the understanding of its causes pathogenesis contribute to disease stigmatization among cardiology medical community. Obesity is a chronic, relapsing, multifactorial characterized by excessive formation adipose tissue, progressing in natural course and, as rule, having an increased cardiometabolic risk. For effective prevention complications, it necessary start treating at risk pre-disease stages (abdominal overweight). The include genetic, metabolic, social environmental factors. review emphasizes not exclusively consequence lack willpower choosing food products according rules healthy eating or sedentary lifestyle. Many stereotypes, such idea all patients with excess body weight have alimentary genesis clinical "findings" are associated obesity, do correspond reality hinder treatment strategies. No other chronic non-communicable stigmatized obesity. Moreover, despite development modern pharmacotherapy, behavioral therapy for bariatric surgery, there high inertia timely initiation this disease. Body becoming same target indicator general therapeutic practice blood pressure glycemia. Modern medicine dictates need rely solely on evidence base refute order create more inclusive supportive environment promotes health well-being patients.

Language: Английский

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