Surveillance of SARS-CoV-2 Infection in Rodent Populations in Tokyo, Japan DOI Open Access
Yudai Kuroda, Akitoyo Hotta,

Masakatsu Taira

et al.

Japanese Journal of Infectious Diseases, Journal Year: 2024, Volume and Issue: 77(6), P. 342 - 344

Published: July 30, 2024

The maintenance of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) among wildlife populations poses a potential risk for the emergence novel variants. Therefore, monitoring SARS-CoV-2 infection animals is crucial. As urban rodents live in close proximity to human habitats, there concern that they may be source zoonoses. To examine prevalence rodent populations, we analyzed 128 serum samples and 129 oral swabs collected from brown rats (Rattus norvegicus) black rattus) captured pest control purposes Tokyo, Japan, between May December 2023. A virus-neutralizing test using Omicron variant revealed no evidence these populations. Real-time RT-PCR did not detect any RNA-positive rats. These results indicate low probability circulation rat Tokyo.

Language: Английский

One Health Surveillance for SARS-CoV-2 in Non-Human Primates and Small Mammals in Minas Gerais, Brazil DOI Creative Commons
Pedro Augusto Almeida-Souza,

Thamires Gabriele Macedo Silva,

Gabriele Barbosa Penha

et al.

Pathogens, Journal Year: 2025, Volume and Issue: 14(4), P. 356 - 356

Published: April 6, 2025

Although the SARS-CoV-2 pandemic primarily affected human population, virus has also been detected in various animal species worldwide, raising concerns about its potential to establish new reservoirs. This study aimed investigate presence of non-human primates (NHPs) and synanthropic small mammals (SSMs) Jequitinhonha Valley Northern Minas Gerais, Brazil. Between October 2021 2023, 119 animals were sampled, 82 NHPs 37 SSMs, across 22 municipalities. A total 342 biological samples-including oral nasal swabs, lungs, livers, spleens, blood, feces-were collected analyzed using RT-qPCR, while serum samples submitted neutralization tests. Despite diversity sampled species, habitats, materials, no evidence infection or specific antibodies was any individuals tested. The results suggest that SSMs these regions did not act as reservoirs for during period. finding is particularly relevant given high synanthropy such Callithrix penicillata (black-tufted marmoset) Rattus rattus (black rat), which frequently interact with populations. Our underscores importance integrating animal, human, environmental health perspectives under a One Health framework monitor emerging zoonotic threats. By providing baseline data on dynamics wildlife, we emphasize need ongoing ecological epidemiological surveillance assess spillover events their implications biodiversity public

Language: Английский

Citations

0
Molecular and Serological Survey of SARS‐CoV‐2 in Murid Rodents From Central Chile DOI

Cesar Kope Grisolia,

Gabriela Muñoz, Rodrigo Salgado

et al.

Zoonoses and Public Health, Journal Year: 2025, Volume and Issue: unknown

Published: April 27, 2025

ABSTRACT The potential role of rodents as reservoirs for SARS‐CoV‐2 has gained global attention due to their proximity humans and involvement in zoonotic disease transmission. Rodents were sampled from urban, rural natural areas across the Metropolitan Region Chile between June 2023 2024. Molecular testing (RT‐qPCR) revealed no active infections among 421 analysed individuals, while serological assays (ELISA) detected antibodies 4 459 (0.87%). All seropositive Rattus rattus captured areas. These findings suggest localised exposure SARS‐CoV‐2, possibly influenced by environmental or anthropogenic factors. results align with studies reporting sporadic rodent emphasising importance integrating molecular approaches surveillance. Despite low prevalence observed, viral spillover recombination events other coronaviruses underscores need continued monitoring. contribute understanding dynamics inform public health strategies a One Health framework.

Language: Английский

Citations

0
Infectious potential and circulation of SARS-CoV-2 in wild rats DOI Creative Commons

Kevyn Beissat,

Virginie Lattard, Evelyne Picard‐Meyer

et al.

PLoS ONE, Journal Year: 2025, Volume and Issue: 20(5), P. e0316882 - e0316882

Published: May 12, 2025

Since the beginning of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, a wide range animal species (pets, mink…) have been naturally infected with this betacoronavirus. The emergence new variants has increased ability SARS-CoV-2 to infect that were not susceptible “original” SARS-CoV-2, such as mice and rats. This work attempted evaluate role urban rats in transmission by combining surveillance studies rat populations environments, vivo experimental inoculation comparative viral-receptor interaction silico analyses. We studied circulation wild Rattus norvegicus (n = 401) captured areas sewage systems several French cities. Except for 3 inconclusive samples (2/75 from Bordeaux 1/261 Lyon) none 353 sera tested showed anti-SARS-CoV-2 antibodies microsphere immunoassay. However, negative virus neutralisation assay. No viral RNA was detected all lungs collected 401 brown In complement, four groups (two wild-type colonies, rattus , two laboratory strains, Sprague-Dawley Wistar) inoculated Omicron BA.5. At 4 days post-inoculation, no infectious particles upper tract (URT) while at low level only URT groups. addition, seroconversion observed 14 after By molecular modelling, BA.5 receptor binding domain (RBD) had lower affinities ACE2 than Homo sapiens ACE2. Based on these results unable type study different France SARS-CoV-2.

Language: Английский

Citations

0
SARS-CoV-2 infection in synanthropic rats from Guayaquil city (Ecuador) during COVID-19 pandemic: a proxy to prevent wild reservoirs in the tropics DOI
Solón Alberto Orlando,

Maria Daniela Mera,

Naomi Mora Jaramillo

et al.

Acta Tropica, Journal Year: 2024, Volume and Issue: 259, P. 107371 - 107371

Published: Aug. 27, 2024

Language: Английский

Citations

2
Surveillance of SARS-CoV-2 Infection in Rodent Populations in Tokyo, Japan DOI Open Access
Yudai Kuroda, Akitoyo Hotta,

Masakatsu Taira

et al.

Japanese Journal of Infectious Diseases, Journal Year: 2024, Volume and Issue: 77(6), P. 342 - 344

Published: July 30, 2024

The maintenance of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) among wildlife populations poses a potential risk for the emergence novel variants. Therefore, monitoring SARS-CoV-2 infection animals is crucial. As urban rodents live in close proximity to human habitats, there concern that they may be source zoonoses. To examine prevalence rodent populations, we analyzed 128 serum samples and 129 oral swabs collected from brown rats (Rattus norvegicus) black rattus) captured pest control purposes Tokyo, Japan, between May December 2023. A virus-neutralizing test using Omicron variant revealed no evidence these populations. Real-time RT-PCR did not detect any RNA-positive rats. These results indicate low probability circulation rat Tokyo.

Language: Английский

Citations

0