Interactions among tuberculosis, geographic environment and aerosols: evidence from the Kashgar region of China DOI Creative Commons
Bo Shang,

Chengjing Wei,

Chenchen Wang

et al.

Frontiers in Public Health, Journal Year: 2025, Volume and Issue: 13

Published: March 19, 2025

Background Aerosols can affect human health through mechanisms like inflammation, oxidative stress, immune dysregulation, and respiratory impairment. In high-pollution areas, airborne particles may promote the transmission of pathogens such as Mycobacterium tuberculosis . This study investigates spatiotemporal distribution tuberculosis, its association with air pollution, potential sources in geographically unique Kashgar region Xinjiang, encircled by mountains desert. Methods Kriging interpolation time series observation were used to analyze trends identify hot cold spots (TB) incidence quality Xinjiang from 2011 2023. Kruskal-Wallis multiple comparisons applied assess regional differences. Meteorological clustering trajectory analysis identified pollutant pathways source hypotheses proposed for TB routes. Results The interaction between geographic environment, aerosols reveals a consistent spatial index (AQI) incidence, overlapping hotspots spots. rate is “ n /100,000.”Southern shows higher (235.31 ± 92.44) poorer (AQI: 64.19 11.73) compared Northern (TB: 83.82 21.43, AQI: 53.90 6.48). Significant differences ( p < 0.0001) confirmed, post-hoc analyses indicating rates worse Southern Xinjiang. Trajectory concentration-weighted (WCWT) dust Taklimakan Desert major contributor PM 2.5 10 values exceeding 150 μg/m 3 400 key areas Aksu Kashgar. Kunlun Tianshan mountain ranges serve barriers that trap migrating dust, while meteorological patterns indicate dust-laden trajectories extend further into mountainous areas. phenomenon exacerbates spread high-risk regions southern Conclusion highlights distinct TB, Poor elevated overlap, particularly Here, Desert, trapped mountains, intensifies contributing

Language: Английский

Interactions among tuberculosis, geographic environment and aerosols: evidence from the Kashgar region of China DOI Creative Commons
Bo Shang,

Chengjing Wei,

Chenchen Wang

et al.

Frontiers in Public Health, Journal Year: 2025, Volume and Issue: 13

Published: March 19, 2025

Background Aerosols can affect human health through mechanisms like inflammation, oxidative stress, immune dysregulation, and respiratory impairment. In high-pollution areas, airborne particles may promote the transmission of pathogens such as Mycobacterium tuberculosis . This study investigates spatiotemporal distribution tuberculosis, its association with air pollution, potential sources in geographically unique Kashgar region Xinjiang, encircled by mountains desert. Methods Kriging interpolation time series observation were used to analyze trends identify hot cold spots (TB) incidence quality Xinjiang from 2011 2023. Kruskal-Wallis multiple comparisons applied assess regional differences. Meteorological clustering trajectory analysis identified pollutant pathways source hypotheses proposed for TB routes. Results The interaction between geographic environment, aerosols reveals a consistent spatial index (AQI) incidence, overlapping hotspots spots. rate is “ n /100,000.”Southern shows higher (235.31 ± 92.44) poorer (AQI: 64.19 11.73) compared Northern (TB: 83.82 21.43, AQI: 53.90 6.48). Significant differences ( p < 0.0001) confirmed, post-hoc analyses indicating rates worse Southern Xinjiang. Trajectory concentration-weighted (WCWT) dust Taklimakan Desert major contributor PM 2.5 10 values exceeding 150 μg/m 3 400 key areas Aksu Kashgar. Kunlun Tianshan mountain ranges serve barriers that trap migrating dust, while meteorological patterns indicate dust-laden trajectories extend further into mountainous areas. phenomenon exacerbates spread high-risk regions southern Conclusion highlights distinct TB, Poor elevated overlap, particularly Here, Desert, trapped mountains, intensifies contributing

Language: Английский

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