Distinct Neural Activities in Hippocampal Subregions Revealed Using a High-Performance Wireless Microsystem with PtNPs/PEDOT:PSS-Enhanced Microelectrode Arrays

Biosensors, Journal Year: 2025, Volume and Issue: 15(4), P. 262 - 262

Published: April 18, 2025

Wireless microsystems for neural signal recording have emerged as a solution to overcome the limitations of tethered systems, which restrict mobility subjects and introduce noise interference. However, existing often face data throughput, processing, long-distance wireless transmission challenges. This study presents high-performance microsystem capable 32-channel, 30 kHz real-time recording, featuring Field Programmable Gate Array (FPGA)-based processing reduce load. The is integrated with platinum nanoparticles/poly (3,4-ethylenedioxythiophene) polystyrene sulfonate-enhanced microelectrode arrays improved quality. A custom NeuroWireless platform was developed seamless reception storage. Experimental validation in rats demonstrated microsystem’s ability detect spikes local field potentials from hippocampal CA1 CA2 subregions. Comparative analysis signals revealed distinct activity patterns between these achieves high accuracy throughput over distances up m, demonstrating its resilience potential neuroscience research. work provides compact, adaptable multi-channel detection offers foundation future applications brain–computer interfaces.

Language: Английский

Recent Advances in Intracortical Neural Interfaces for Freely Moving Animals: Technologies and Applications

Engineering, Journal Year: 2024, Volume and Issue: 44, P. 73 - 86

Published: Dec. 20, 2024

Language: Английский