The relationship between the state of cerebral blood flow and volemic status in patients with ischemic stroke in the acute period
Messenger of Anesthesiology and Resuscitation,
Journal Year:
2024,
Volume and Issue:
21(5), P. 50 - 57
Published: Oct. 19, 2024
The
objective
was
to
assess
the
relationship
between
state
of
cerebral
blood
flow
and
volemic
status
in
patients
with
acute
ischemic
stroke
using
laboratory
instrumental
parameters.
Materials
methods
.
51
newly
diagnosed
confirmed
by
MSCT/MRI
brain
were
examined
within
less
than
24
hours
from
onset
disease,
20
practically
healthy
individuals
(control
group).
To
determine
flow,
hemodynamic
parameters
transcranial
Doppler
imaging
used:
rates
(maximum
systolic,
diastolic,
averaged
over
time),
Gosling’s
pulsatility
index
Purcelo’s
peripheral
resistance
anterior,
posterior,
middle
main
arteries
affected
intact
sides.
Volemic
assessed
(serum
sodium
natriuretic
peptide
NT-pro-BNP)
(echocardiography
–
end-diastolic
volume
left
ventricle,
ventricular
ejection
fraction,
diameter
degree
collapse
on
inhalation
inferior
vena
cava).
Results.
Deterioration
speed
indicators
an
increase
vascular
wall
noted
studied
against
background
violations
level
peptide,
cava,
fraction
cava.
There
is
a
correlation
volemia,
since
both
development
deficiency
overload
negatively
affect
perfusion.
Conclusions.
are
correlated
period.
Language: Английский
Arterial pressure during first day after intravenous thrombolysis and acute ischemic stroke outcomes: single-center randomized controlled study
Messenger of Anesthesiology and Resuscitation,
Journal Year:
2024,
Volume and Issue:
21(6), P. 42 - 50
Published: Dec. 27, 2024
Introduction
.
Blood
pressure
optimization
during
and
after
reperfusion
in
patients
with
acute
ischemic
stroke
can
reduce
the
risk
of
hemorrhagic
complications
improve
functional
recovery.
Several
randomized
controlled
trials
different
target
blood
values
have
been
published
varying
results.
The
objective
was
to
evaluate
effect
intensive
hypotensive
therapy
first
day
intravenous
thrombolysis
on
outcomes
incidence
complications.
Materials
methods
A
single-center
open
label
trial
conducted.
Patients
older
than
18
years
who
underwent
were
included.
into
2
groups:
a
systolic
161–185
mm
Hg
(control
group)
versus
<
160
(intensive
group).
primary
end
points
mortality
modified
Rankin
Scale
score
at
90
from
onset
stroke.
Results
final
analysis
included
69
patients.
In
group,
rate
did
not
differ
control
group:
OR
1.1
[95%
CI
0.3
4.8]
(p
=
0.896).
median
scale
group
(1;
3.8)
3.5)
0.812).
Conclusion
Intensive
compared
conventional
neither
improved
outcome
nor
decreased
Language: Английский