PHYSIOCHEMICAL PROPERTIES OF DRINKING WATER IN THE VILLAGE OF ARKHANGELSKOYE, ARKHANGELSK REGION, REPUBLIC OF BASHKORTOSTAN DOI Open Access

I.V. Ilina,

E.E. Papyan,

A.A. Yarmullin

et al.

Published: Dec. 11, 2024

The article substantiates the need for economic growth country, analyzes indicators of Russian and Chinese economies, presents a methodological approach to comprehensive assessment development countries, and, based on linear regression analysis, identifies sectors that have greatest impact countries' GDP growth.The expedient innovative cooperation between Russia China is substantiated as factor further both countries.

Language: Английский

Chronic heart failure in the Russian Federation: what has changed over 20 years of follow-up? Results of the EPOCH-CHF study DOI Creative Commons
D. S. Polyakov, И. В. Фомин, Yu. N. Belenkov

et al.

Kardiologiia, Journal Year: 2021, Volume and Issue: 61(4), P. 4 - 14

Published: May 6, 2021

Aim To study the etiology and dynamics of prevalence mortality CHF; to evaluate treatment coverage such patients in a representative sample European part Russian Federation for 20-year period. Material methods A followed up 2002 through 2017 (n=19 276); population Nizhny Novgorod region examined 1998 (n=1922). Results During observation period since 2002, incidence major CHF symptoms (tachycardia, edema, shortness breath, weakness) tended decrease while cardiovascular diseases has statistically significantly increased. from 2017, I-IV functional class (FC) increased 6.1 % 8.2 whereas III-IV FC 1.8 3.1 %. The main causes development remained arterial hypertension ischemic heart disease; role myocardial infarction diabetes mellitus as was noted. For analyzed period, number components basic therapy with increased, which probably accounts slower increase disease by 2007–2017. prognosis unfavorable: I-II CHF, median survival 8.4 (95 CI: 7.8–9.1) years 3.8 3.4–4.2) years.

Language: Английский

Citations

160

Modern content and improvement of high cardiovascular risk strategy in reducing mortality from cardiovascular diseases DOI Creative Commons
S. А. Boytsov, О. М. Драпкина

Terapevticheskii arkhiv, Journal Year: 2021, Volume and Issue: 93(1), P. 4 - 6

Published: Jan. 10, 2021

The article describes the modern content of high-risk strategy, which, along with population forms basis a set measures to reduce mortality from cardiovascular diseases. high risk strategy is carried out at individual level in outpatient structures as part primary and secondary prevention diseases, also implemented hospitals when performing elective surgical procedures, including high-tech interventions. Improving this within framework health care involves development system offices, telemedicine consulting, remote monitoring physiological parameters on regional medical information system, future, uniform vertically integrated system. inpatient practice occurs through further replication technologies implementation new types them.

Language: Английский

Citations

34

Clusters of patients with chronic heart failure based on the analysis of body composition parameters and palliative status DOI Creative Commons
V. I. Shevtsova, Anna A. Pashkova, А. Н. Шевцов

et al.

Bulletin of the Medical Institute REAVIZ (REHABILITATION DOCTOR AND HEALTH), Journal Year: 2025, Volume and Issue: 15(1), P. 72 - 78

Published: March 20, 2025

The aim of the study : to divide a heterogeneous group patients with chronic heart failure, taking into account parameters body composition and severity painful symptoms. Object methods . involved 298 CHF. was assessed: presence sarcopenia obesity (with calculation muscle mass index), functional class, left ventricular ejection fraction, markers galectin-3, hsCRP sodium uretic peptide, Bartel index. A 10-point Edmont scale used assess two-stage cluster analysis performed. Results Three clusters were identified in patient structure: share first overall structure 23.2%, second – 61.1%, third 15.8%. It determined that includes sarcopenic obesity. They are characterized by maximum galectin level fraction sample. have low walking speed, dynamometry, NТ-proBNP. intermediate position is occupied (patients isolated disorder or without it). high dynamometry indicators, 6-minute test value, Barthel Patients people weight sarcopenia. Sarcopenia Fast questionnaire T6W indicators significantly reduced fractions NТ-proBNP level. most pronounced pain fatigue lowest depression. In cluster, pain, fatigue, drowsiness, nausea, shortness breath, anxiety, well-being expressed much less than other clusters. And highest appetite disorders, depression, deterioration well-being. Conclusions distressing symptoms varies depending on and, accordingly, patient's composition, which can be constructing algorithms for providing palliative care

Language: Английский

Citations

0

Clinical and anamnestic predictors of poor long-term prognosis in patients with chronic heart failure and implanted cardioverter-defibrillator DOI Creative Commons

Nataliya B. Lebedeva,

I. V. Talibullin,

P. G. Parfenov

et al.

Terapevticheskii arkhiv, Journal Year: 2025, Volume and Issue: 97(1), P. 21 - 28

Published: Feb. 20, 2025

Aim. Identification of a complex clinical and anamnestic predictors an unfavorable long-term prognosis in patients with heart failure low left ventricular ejection fraction implanted cardioverter-defibrillator (ICD). Materials methods. In 260 ICD included the ”Kuzbass Register Patients ICD”, data were obtained on status alive/dead, causes death cardiovascular events during 4-year follow-up period. The clinical-instrumental socio-demographic parameters entered into register before implantation used to compile prognostic regression model. Results. A total 348 (endpoints) recorded, which 54 deaths. main cause 48 (88.9%) was acute decompensated failure. According multivariate analysis, factors that increase risk outcome model were: level systolic pressure pulmonary artery, thickness interventricular septum, social status, presence chronic obstructive disease, ventricle absence renin-blocker angiotensin-aldosterone system (model sensitivity – 70%, specificity 75.9%, AUC=0.8). Conclusion. use predictive practice will make it possible personalize approaches making decision need for further monitoring order improve their survival.

Language: Английский

Citations

0

Chronic heart failure with preserved ejection fraction: current understanding of the problem DOI Open Access
О. А. Пономарева, Vladimir E. Vladimirskiy, I.V. Petukhova

et al.

Perm Medical Journal, Journal Year: 2025, Volume and Issue: 42(1), P. 12 - 19

Published: March 13, 2025

This review is aimed at the investigation of diagnostic approaches and therapeutic options for patients with chronic cardiac insufficiency preserved ejection fraction. Chronic fraction can result from various cardiovascular diseases observed in more than 50 % circulatory failure. Although clinical guidelines exist, criteria diagnosing this form heart failure do not always allow to detect disease accurately, which affect subsequent treatment negatively. Modern randomized trials demonstrate that medications group sodium-glucose cotransporter type-2 inhibitors significantly improve outcomes failure, justifying their inclusion regimen. However, optimal time starting therapy still questionable compared administration other recommended insufficiency. Considering high incidence, difficulties diagnosis practice, development practical algorithms detecting managing condition one most important tasks.

Language: Английский

Citations

0

Factors associated with the risk of progression and decompensation of heart failure in patients with an implantable cardioverter-defibrillator DOI Creative Commons

Н. Б. Лебедева,

I. V. Talibullin,

P. G. Parfenov

et al.

Russian Journal of Cardiology, Journal Year: 2024, Volume and Issue: 29(3), P. 5619 - 5619

Published: April 18, 2024

Aim. To analyze clinical and anamnestic factors associated with the risk of acute decompensated heart failure (ADHF) in patients an implanted cardioverter-defibrillator (ICD) development a prognostic model based on Kuzbass registry ICD. Material methods . Prospective follow-up 260 reduced left ventricular ejection fraction (age 59 (53; 66) years, 214 (82,3%) men) from Of them, 156 (60%) had ischemic cardiomyopathy, while rest non-ischemic cardiomyopathy. The mean period was 4,2±2,3 years after ICD implantation. following basic information about were assessed: demographic data, social status, history underlying disease, concomitant diseases, vital signs, standard paraclinical parameters, drug therapy. During period, all cases ADHF death analyzed. Results. A total 54 (20,8%) died, which 48 (88,9%) died due to ADHF. 34 hospitalized for ADHF, 13 (38,2%) died. Thirty-five (13,5%) prehospital stage that developed against background disease (10 (27%) dilated 1 (2,8%) — rheumatic mitral valve 24 (68,6%) cardiomyopathy). Thus, 69 registered, accounted 26,5% group. Mortality general group 18,5%. According Kaplan-Meier curve, most deaths occurred during first 1,5 follow-up. regression predicting included atrium size (p=0,05), male sex (p=0,001), NYHA class (p=0,0001), <40% no intake renin-angiotensin-aldosterone system inhibitors (p=0,007) amiodarone (p=0,028). area under ROC curve (AUC), sensitivity specificity created 0,8, 69,2% 80%, respectively. Conclusion. set routine has been identified makes it possible predict ICDs, must be taken into account before making decision implant device. Particular attention should paid mandatory therapy failure, as main modifiable factor

Language: Английский

Citations

2

Total, ageand sex-specific mortality after discharge of patients with heart failure: the first large-scale cohort real-world study on Russian population DOI Creative Commons
A. E. Soloveva, Alexei Medvedev, A. V. Lubkovsky

et al.

Russian Journal of Cardiology, Journal Year: 2024, Volume and Issue: 29(6), P. 5940 - 5940

Published: May 12, 2024

Aim. To assess total, ageand sex-specific survival rate after discharge of patients with heart failure (HF) using real-world electronic health data. Material and methods. This retrospective analysis data from the St. Petersburg Chronic Heart Failure Registry was performed. Hospitalizations aged 18 years a diagnosis code I50.x (International Classification Diseases, 10 th revision) were included in period January 1, 2019 to December 31, 2023. Cases acute myocardial infarction, cerebrovascular accident, coronavirus disease 2019, hospitalization duration >30 days, death during current not included. Results. The study 73450 99 (mean age, 73±12 years; women, 59,1%). During median follow-up 388 16212 (22,1%) died. cumulative probability within one five 16,3% 48,9%. At each time period, higher men when stratified by age as increased. mortality 15,3 (95% confidence interval 15,1 15,6) per 100 patientyears. For all subgroups, highest value recorded first month (50,1 patient-years), reaching maximum subgroup elderly senile (60,7 patient-years). Conclusion. Within 1 year 5 hospital discharge, 48,9% HF die, respectively. risk is typical especially for patients.

Language: Английский

Citations

2

Principles of organization of medical care for patients with heart failure in the system of cardiovascular risk management: focus on continuity of care and patient routing. Practical materials DOI Creative Commons
S. Villevalde, A. E. Soloveva, Н. Э. Звартау

et al.

Russian Journal of Cardiology, Journal Year: 2021, Volume and Issue: 26(3S), P. 4558 - 4558

Published: Oct. 13, 2021

The extent of the problem heart failure determines priority intention developing and implementing an optimal model medical care for this group patients. article describes key components (continuity, patient routing, educational activities) provides examples documents, protocols, checklists that can be used in real clinical practice by specialists organizations regions Russian Federation.

Language: Английский

Citations

15

External validation of a multivariate model for predicting the risk of death in patients with chronic heart failure and an implantable cardioverter – defibrillator DOI Creative Commons

Н. Б. Лебедева,

P. G. Parfenov,

A. P. Egle

et al.

Bulletin of Siberian Medicine, Journal Year: 2024, Volume and Issue: 23(2), P. 74 - 82

Published: July 10, 2024

Aim . To perform external validation of a multivariate model for predicting the risk death in patients with an implantable cardioverter – defibrillator (ICD) independent sample. Materials and methods The group development included 260 from Implantable Cardioverter Defibrillator Patient Registry who had ICD implanted between 2015 2019. External was carried out independent, prospective, observational cohort study same registry, whom 2020 2021, total 94 patients, median age 66 (52;73) years, 73 (77.6%) men, 21 (22.4%) women. In 89 (94.7%) primary prevention sudden cardiac death. Following telephone survey examination medical records hospital clinic databases, data on vital status (alive / dead) causes were obtained during 2.5-year follow-up. actual predicted mortality estimated compared. Results During follow-up, 26 (27.7%) died group, which comparable to (p > 0.05). deceased, 15 (57.7%) people developed acute decompensated heart failure, 4 (14.8%) myocardial infarction, 6 (23.1%) pneumonia caused by new coronavirus infection, one (3.8%) patient due infectious complication. diagnostic accuracy sample sufficient (the area under curve (AUC) created 0.8). sensitivity 76.2%, specificity 76.1%. Previously, cohort, AUC 0.8, 75.7%, 80%. Model significance did not differ significantly groups = 0.102, McNeil test). Conclusion prediction has statistical power predict long-term after implantation, externally validated.

Language: Английский

Citations

1

ICD-10 code-based definition of heart failure in Saint Petersburg electronic health records: prevalence, health care utilization and outcomes DOI Creative Commons
A. E. Soloveva, G. V. Endubaeva,

N. G. Avdonina

et al.

Russian Journal of Cardiology, Journal Year: 2021, Volume and Issue: 26(3S), P. 4621 - 4621

Published: Oct. 13, 2021

Aim . To analyze prevalence of heart failure (HF), clinical and demographic characteristics, health care utilization, outcomes according to the used International Statistical Classification Diseases Related Health Problems 10th Revision (ICD-10) codes in regional integrated electronic record database Saint Petersburg. Material methods The retrospective analysis Petersburg for 2019 was performed. At least one following ICD-10 has been considered as HF case: I50.x (standard coding) and/or I11.0, I13.0, I13.2, I25.5, I42.0, I42.9, I09.9, I43.0, I43.1, I43.2, I43.8, I42.5, I42.6, I42.7, I42.8 (extended coding). Results A total 64070 adult patients with had medical encounters 2019, 34,5% whom were identified using standard coding, 65,5% — extended coding. combination observed 9,9% cases. prevalence/mortality 1,4%/6,8% general, well 0,49%/15,7% 0,93%/2,1% respectively. high healthcare utilization mean number 14 per patient year. Actually, 24% more than 20 both inpatient outpatient 54% at 1 all-cause hospitalization during Encounters accounted 4,3% all visits, 6,5% hospitalizations, 4,1% visits 9,7% emergency contacts Patients by coding compared older age higher incidence comorbidities, greater death rates, but lower visits. Conclusion among population Saint. 1,4%. characterized a mortality rate reaching 15,7 % use different approaches presumably could help identify groups HF, which requires adaptation models an active monitoring system reduce risk adverse events.

Language: Английский

Citations

6