Bioresource collections: algorithms for development and functioning; basic and applied significance DOI Creative Commons
Е. Н. Кособокова, N. A. Kalinina, М. А. Барышникова

et al.

CARDIOVASCULAR THERAPY AND PREVENTION, Journal Year: 2023, Volume and Issue: 22(11), P. 3654 - 3654

Published: Dec. 9, 2023

Bioresource collection of the N. Blokhin National Medical Research Center Oncology is a unique structured biobank that combines different types primary and subsidiary samples ensures its comprehensive characterization, including both generally accepted indicators specific research. Samples paraffin blocks, frozen material, blood derivatives are deposited in clinical department center. The research institute center has collected commercial human cell lines transplantable strains obtained from as well cells laboratory animals, mainly mouse origin. provided undergo multi- stage quality control, confirmation authenticity, assessment viability determination optimal cultivation conditions, analysis interspecific intraspecific contamination, study tumorigenicity reproducibility athymic Balb/ c-nude mice, etc. In addition, Collection hybridoma clones produce antibodies to wide range targets. provides opportunity conduct preclinical using obtain scientific regulatory data on antiproliferative activity new agents or methods for cancer treatment.

Language: Английский

Bioresource collections: algorithms for development and functioning; basic and applied significance DOI Creative Commons
Е. Н. Кособокова, N. A. Kalinina, М. А. Барышникова

et al.

CARDIOVASCULAR THERAPY AND PREVENTION, Journal Year: 2023, Volume and Issue: 22(11), P. 3654 - 3654

Published: Dec. 9, 2023

Bioresource collection of the N. Blokhin National Medical Research Center Oncology is a unique structured biobank that combines different types primary and subsidiary samples ensures its comprehensive characterization, including both generally accepted indicators specific research. Samples paraffin blocks, frozen material, blood derivatives are deposited in clinical department center. The research institute center has collected commercial human cell lines transplantable strains obtained from as well cells laboratory animals, mainly mouse origin. provided undergo multi- stage quality control, confirmation authenticity, assessment viability determination optimal cultivation conditions, analysis interspecific intraspecific contamination, study tumorigenicity reproducibility athymic Balb/ c-nude mice, etc. In addition, Collection hybridoma clones produce antibodies to wide range targets. provides opportunity conduct preclinical using obtain scientific regulatory data on antiproliferative activity new agents or methods for cancer treatment.

Language: Английский

Citations

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