Unraveling Dysgeusia in SARS-CoV-2 Infection: Clinical and Laboratory Insights from Hospitalized COVID-19 Patients in Romania DOI Creative Commons

Elena Camelia Kouris,

Sînziana Irina Mirea,

Sigrid Covaci

et al.

Pathogens, Journal Year: 2025, Volume and Issue: 14(4), P. 300 - 300

Published: March 21, 2025

Introduction: Dysgeusia has been regarded as a clinical feature associated with SARS-CoV-2 infection since the onset of pandemic. The initial circulating variants were linked to presence dysgeusia; however, emergence Omicron variant, incidence dysgeusia decreased. aim this study was identify and characteristics patients from pandemic variant. Methods: We conducted retrospective March 2020 December 2021, among adult hospitalized COVID-19 in main infectious diseases hospital Romania. Clinical laboratory data collected interpreted relation or absence dysgeusia. Results: 32.0%, majority cases (44.2%) occurring Beta predominantly observed mild moderate disease. obesity hypertension shown be negatively development (OR = 0.45, OR 0.39, respectively). In dysgeusia, inflammatory changes such lymphopenia significantly less frequently identified 0.22, p < 0.001), increased C-reactive protein 0.12, 0.001) interleukin-1 0.42, 0.002), fibrinogen 0.31, ferritin 0.27, compared without acute respiratory failure higher group (71.2% vs. 28.8%, 0.001). This accompanied by milder management median duration hospitalization that two days shorter. Conclusions: appears correlate both response outcome. context evolving viral variants, which seem lower continuous monitoring who develop disorder remains essential clarify pathophysiologic mechanisms involved assess potential predictor course infection.

Language: Английский

The Role of Physical Examination and Clinical Scores in Distinguishing Streptococcal Colonization from Pharyngitis in Pediatric Patients: Insights from a Common Clinical Scenario DOI Creative Commons
Victor Daniel Miron, Doina Anca Pleșca,

Anuța Bilaşco

et al.

Microorganisms, Journal Year: 2025, Volume and Issue: 13(3), P. 529 - 529

Published: Feb. 27, 2025

The accurate differentiation between asymptomatic carriage with group A streptococcus (GAS) and active streptococcal pharyngitis is a complex task important clinical public health implications. This work aims to highlight the key strategies necessary for optimizing diagnostic therapeutic management of pediatric pharyngitis. Clinical scores are essential tools improving accuracy. When combined laboratory tests such as throat cultures rapid antigen detection tests, these systems enable effective risk stratification patients, supporting more precise treatment decisions. In addition strategies, article underscores importance patient-centered communication, particularly families patients. Clear, empathetic discussions about condition, rationale, plan help foster trust, enhance adherence medical recommendations, reduce anxiety related potential complications. critical outcome reduction unnecessary antibiotic use, which plays pivotal role in preventing both overdiagnosis overprescription. This, turn, mitigates growing threat antimicrobial resistance, one most significant global challenges. By integrating expertise, standardized protocols, healthcare providers can promote judicious or carriage, contributing improved individual population outcomes.

Language: Английский

Citations

0
Unraveling Dysgeusia in SARS-CoV-2 Infection: Clinical and Laboratory Insights from Hospitalized COVID-19 Patients in Romania DOI Creative Commons

Elena Camelia Kouris,

Sînziana Irina Mirea,

Sigrid Covaci

et al.

Pathogens, Journal Year: 2025, Volume and Issue: 14(4), P. 300 - 300

Published: March 21, 2025

Introduction: Dysgeusia has been regarded as a clinical feature associated with SARS-CoV-2 infection since the onset of pandemic. The initial circulating variants were linked to presence dysgeusia; however, emergence Omicron variant, incidence dysgeusia decreased. aim this study was identify and characteristics patients from pandemic variant. Methods: We conducted retrospective March 2020 December 2021, among adult hospitalized COVID-19 in main infectious diseases hospital Romania. Clinical laboratory data collected interpreted relation or absence dysgeusia. Results: 32.0%, majority cases (44.2%) occurring Beta predominantly observed mild moderate disease. obesity hypertension shown be negatively development (OR = 0.45, OR 0.39, respectively). In dysgeusia, inflammatory changes such lymphopenia significantly less frequently identified 0.22, p < 0.001), increased C-reactive protein 0.12, 0.001) interleukin-1 0.42, 0.002), fibrinogen 0.31, ferritin 0.27, compared without acute respiratory failure higher group (71.2% vs. 28.8%, 0.001). This accompanied by milder management median duration hospitalization that two days shorter. Conclusions: appears correlate both response outcome. context evolving viral variants, which seem lower continuous monitoring who develop disorder remains essential clarify pathophysiologic mechanisms involved assess potential predictor course infection.

Language: Английский

Citations

0