Research Square (Research Square),
Journal Year:
2021,
Volume and Issue:
unknown
Published: Dec. 14, 2021
Abstract
Objectives
There
is
no
report
on
antibody
titers
after
vaccination
against
SARS-CoV-2
in
Japanese
dialysis
patients.
As
different
between
Japan
and
other
countries,
changes
were
examined.
Methods
Baseline
characteristics
anti-spike
protein
(Roche)
over
90
days
administration
of
the
BNT162b2
messenger
RNA
vaccine
investigated
Results
The
maximum
titer
second
dose
was
737.9
(326.8
to
1143.4)
reached
at
19
(17
24.3)
dose.
Antibody
decreased
time,
with
770
(316.4
1089)
15
days,
385
(203
689.7)
30
253.5
(138
423)
60
208
(107
375)
When
an
137.052
U/mL
assumed
be
a
measure
related
breakthrough
infection,
proportion
subjects
exceeding
this
level
90.1％
85.3%
75.0%
65.4%
decrease
below
defined
as
event,
pre-dialysis
albumin
≥
3.5
significantly
less
likely
experience
event
than
<
3.5.
In
addition,
study
suggests
that
presence
levels
313
might
factor
maintaining
Conclusions
patients
approximately
30%
those
non-dialysis
individuals
reported
otherwise,
it
similar
countries.
Whether
additional
needed
should
determined
based
indicators
serving
factors
well
status
spread
infection.
Polskie Archiwum Medycyny Wewnętrznej,
Journal Year:
2022,
Volume and Issue:
unknown
Published: Sept. 9, 2022
ARTICLE
COVID
-19
in
renal
replacement
therapy
patients
1
against
many
countries,
right
after
health
care
professionals.The
current
review
presents
the
most
important
differences
among
treated
with
terms
of
epidemiology
-19,
course
disease,
prognosis
and
prevention,
as
well
challenges
associated
improving
this
group
on
eve
subsequent
pandemic
waves.
Different
characteristics
patientsIn
CKD,
particularly
those
requiring
therapy,
dysfunction
immune
system
is
found,
consisting
its
accelerated
aging,
weakening
humoral
cellular
functions,
impaired
regulation
proinflammatory
reactions,
chronic
inflammation.
6
Most
such
are
elderly
people
Introduction
Since
outbreak
Wuhan
December
2019,
numerous
reports
have
been
published
that
unequivocally
demonstrate
an
increased
incidence
mortality
from
kidney
disease
(CKD),
is,
hemodialysis
(HD)
transplant
recipients
(KTRs).
Studies
various
countries
shown
population
characterized
by
a
very
severe
COVID-19,
ending
death
almost
every
third
patient.
2
This
led
to
situation
where,
dialysis
centers,
percentage
who
died
during
was
several
times
higher
than
corresponding
period
before
pandemic.
3-5As
consequence,
HD
immunocompromised
individuals
organ
transplantation
were
preferentially
vaccinated
BMC Infectious Diseases,
Journal Year:
2022,
Volume and Issue:
22(1)
Published: Nov. 14, 2022
Abstract
Objectives
There
is
no
report
on
antibody
titers
after
vaccination
against
SARS-CoV-2
in
Japanese
dialysis
patients.
As
different
between
Japan
and
other
countries,
changes
were
examined.
Methods
Baseline
characteristics
anti-spike
protein
(Roche)
over
90
days
administration
of
the
BNT162b2
messenger
RNA
vaccine
investigated
Results
The
maximum
titer
second
dose
was
738
(327
to
1143)
U/mL
reached
at
19
(17
24)
dose.
Antibody
decreased
time,
with
770
(316
1089)
15
days,
385
(203
690)
30
254
(138
423)
60
208
(107
375)
When
an
137
assumed
be
a
measure
related
breakthrough
infection,
proportion
subjects
exceeding
this
level
90.1%
85.3%
75.0%
65.4%
decrease
below
defined
as
event,
pre-dialysis
albumin
≥
3.5
g/dL
significantly
less
likely
experience
event
than
<
g/dL.
Conclusions
presence
levels
313
might
factor
maintaining
enough
after.
Whether
additional
needed
should
determined
based
indicators
serving
factors
well
status
spread
infection.
Research Square (Research Square),
Journal Year:
2021,
Volume and Issue:
unknown
Published: Dec. 14, 2021
Abstract
Objectives
There
is
no
report
on
antibody
titers
after
vaccination
against
SARS-CoV-2
in
Japanese
dialysis
patients.
As
different
between
Japan
and
other
countries,
changes
were
examined.
Methods
Baseline
characteristics
anti-spike
protein
(Roche)
over
90
days
administration
of
the
BNT162b2
messenger
RNA
vaccine
investigated
Results
The
maximum
titer
second
dose
was
737.9
(326.8
to
1143.4)
reached
at
19
(17
24.3)
dose.
Antibody
decreased
time,
with
770
(316.4
1089)
15
days,
385
(203
689.7)
30
253.5
(138
423)
60
208
(107
375)
When
an
137.052
U/mL
assumed
be
a
measure
related
breakthrough
infection,
proportion
subjects
exceeding
this
level
90.1％
85.3%
75.0%
65.4%
decrease
below
defined
as
event,
pre-dialysis
albumin
≥
3.5
significantly
less
likely
experience
event
than
<
3.5.
In
addition,
study
suggests
that
presence
levels
313
might
factor
maintaining
Conclusions
patients
approximately
30%
those
non-dialysis
individuals
reported
otherwise,
it
similar
countries.
Whether
additional
needed
should
determined
based
indicators
serving
factors
well
status
spread
infection.
