Bioactive Materials, Journal Year: 2024, Volume and Issue: 46, P. 213 - 228
Published: Dec. 16, 2024
Language: Английский
Matter, Journal Year: 2025, Volume and Issue: 8(3), P. 101989 - 101989
Published: Feb. 12, 2025
Language: Английский
Citations
1
Advances in Colloid and Interface Science, Journal Year: 2025, Volume and Issue: unknown, P. 103477 - 103477
Published: March 1, 2025
Language: Английский
Citations
0
ACS Biomaterials Science & Engineering, Journal Year: 2025, Volume and Issue: unknown
Published: April 1, 2025
Hydrogel wound dressings have emerged as a promising solution for healing due to their excellent mechanical and biochemical properties. Over recent years, there has been significant progress in expanding the variety of raw materials used hydrogel formulation along with development advanced modification techniques design approaches that enhance performance. However, comprehensive review encompassing diverse polymer strategies innovations is still lacking literature. This summarizes use natural polymers (e.g., chitosan, gelatin, sodium alginate, hyaluronic acid, dextran) synthetic poly(vinyl alcohol), polyethylene glycol, Pluronic F-127, poly(N-isopropylacrylamide), polyacrylamide, polypeptides) dressings. We further explore advantages limitations these discuss various strategies, including cationic modification, oxidative double-bond catechol etc. The also addresses principles synthesis methods, aligning modifications specific requirements healing. Finally, we future challenges opportunities hydrogel-based
Language: Английский
Citations
0
Revista Sociedade Científica, Journal Year: 2025, Volume and Issue: 8(1), P. 786 - 803
Published: April 14, 2025
As queimaduras encaixam-se em um contexto clínico capaz de gerar uma exposição do paciente, ocasionando danos físicos e psicológicos, apresentando-se como problema agudo na saúde pública mundo. Busca-se avaliar a efetividade produtos derivados da pele tilápia Nilo no auxílio cicatrização pele, forma inovadora promissora. O trabalho apresentado é revisão sistemática, ao qual foi feita busca PUBMED, BVS, WEB OF SCIENCE SCIENCEDIRECT, realizada identificação ensaios clínicos que compararam curativos tradicionais. Os desfechos buscados foram repetelização melhora dor frequência troca curativo. De 88 artigos, 4 estudos incluídos após análise dos critérios inclusão exclusão, sendo os realizados entre 2017 2024. materiais possuíram melhor taxa tempo cicatrização, diminuição menor curativo quando comparada aos métodos tradicionais tratamento queimaduras. Entretanto, apesar boas evidências para essas intervenções, maioria ainda carece qualidade testes humanos. Levando base resultados, conclui-se utilização pacientes com oferece diversas vantagens relação à terapia convencional.
Citations
0
Materials Futures, Journal Year: 2025, Volume and Issue: 4(2), P. 025402 - 025402
Published: April 23, 2025
Abstract Microneedles have demonstrated valuable applications in diabetic wound management. Many endeavors are devoted to developing microneedles with well-designed structures and enhanced functions. Herein, we present an elaborate microneedle patch breathability for healing by a multi-step replication method. The consists of breathable porous supporting substrate core–shell tips involving poly (vinyl alcohol) shells loaded antimicrobial peptides (PVA@AMPs shell) crosslinked Gelma cores encapsulated exosomes (Gelma@exo core). PVA was ROS-responsive linker, which results degradation the shell inflammatory microenvironment, thus inducing release AMPs inhibit bacteria. Further, continuously from exposed Gelma@exo core, promoting tissue regeneration regulating immune response. Besides, high porosity makes patches more suitable chronic wounds. Based on these features, it that exhibits desirable performance vivo animal tests. Thus, believe proposed remarkable potential related fields.
Language: Английский
Citations
0
Frontiers in Bioengineering and Biotechnology, Journal Year: 2025, Volume and Issue: 13
Published: May 12, 2025
Chronic wounds pose a substantial burden on healthcare systems, necessitating innovative tissue engineering strategies to enhance clinical outcomes. Hydrogels, both of natural and synthetic origin, have emerged as versatile biomaterials for wound management due their structural adaptability, biocompatibility, tunable physicochemical properties. Their hydrophilic nature enables efficient nutrient transport, waste removal, cellular integration, while malleability facilitates application deep irregular wounds, providing an optimal microenvironment cell adhesion, proliferation, differentiation. Extracellular matrix (ECM)- based hydrogels retain bioactive molecules that support infiltration, immune modulation, remodelling, making them highly effective scaffolds growth factor delivery regenerative therapies. Additionally, injectability potential in situ polymerization enable minimally invasive applications, allowing on-demand gelation at target sites. By modifying mechanical properties through crosslinking, can achieve enhanced stability, prolonged degradation control, improved surgical handling, optimizing functionality dynamic environments. This review outlines current approaches skin engineering, examining the employed hydrogel design, limitations, interactions with host tissues. Furthermore, it highlights emerging functionalized injectable hydrogels, particularly those engineered controlled drug release, bioactivity, patient-specific therapeutic applications. These offer transformative platform advanced care medicine.
Language: Английский
Citations
0
Materials Today Bio, Journal Year: 2024, Volume and Issue: 30, P. 101408 - 101408
Published: Dec. 18, 2024
Language: Английский
Citations
2
Colloids and Surfaces B Biointerfaces, Journal Year: 2024, Volume and Issue: 248, P. 114488 - 114488
Published: Dec. 30, 2024
Language: Английский
Citations
1
Bioactive Materials, Journal Year: 2024, Volume and Issue: 46, P. 213 - 228
Published: Dec. 16, 2024
Language: Английский
Citations
0