Modelling a Western Lifestyle in Mice: A Novel Approach to Eradicating Aerobic Spore-Forming Bacteria from the Colonic Microbiome and Assessing Long-Term Clinical Outcomes DOI Creative Commons
Edward Horwell, William T. Ferreira,

Huynh A. Hong

et al.

Biomedicines, Journal Year: 2024, Volume and Issue: 12(10), P. 2274 - 2274

Published: Oct. 7, 2024

The environmentally acquired aerobic spore-forming (EAS-Fs) bacteria that are ubiquitous in nature (e.g., soil) transient colonisers of the mammalian gastro-intestinal tract. Without regular exposure, their numbers quickly diminish. These species have been suggested to be essential normal functioning metabolic and immunogenic health. modern Western lifestyle restricts exposure these EAS-Fs, possibly explaining part pathogenesis many diseases. To date, only animal studies address specific microbiome modelling based around germ-free animals. We designed a new model specifically environmental sources bacteria.

Language: Английский

Modelling a Western Lifestyle in Mice: A Novel Approach to Eradicating Aerobic Spore-Forming Bacteria from the Colonic Microbiome and Assessing Long-Term Clinical Outcomes DOI Creative Commons
Edward Horwell, William T. Ferreira,

Huynh A. Hong

et al.

Biomedicines, Journal Year: 2024, Volume and Issue: 12(10), P. 2274 - 2274

Published: Oct. 7, 2024

The environmentally acquired aerobic spore-forming (EAS-Fs) bacteria that are ubiquitous in nature (e.g., soil) transient colonisers of the mammalian gastro-intestinal tract. Without regular exposure, their numbers quickly diminish. These species have been suggested to be essential normal functioning metabolic and immunogenic health. modern Western lifestyle restricts exposure these EAS-Fs, possibly explaining part pathogenesis many diseases. To date, only animal studies address specific microbiome modelling based around germ-free animals. We designed a new model specifically environmental sources bacteria.

Language: Английский

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