Recent Progress in Pd-Catalyzed Tandem Processes
Published: July 11, 2023
In
recent
years
Pd-containing
catalytic
systems
for
tandem
processes
has
drawn
special
attention
due
to
the
enhanced
properties
and
possibility
perform
several
reactions
without
necessity
separate
intermediates.
this
review,
progress
in
Pd-catalyzed
is
considered.
Three
types
of
were
described:
homogeneous
catalysts
(including
immobilized
Pd
complexes);
heterogeneous
supported
on
oxides,
MOFs,
COFs,
etc.
with
particular
supports
containing
acid/base
sites;
metal-enzyme
chemoenzymatic
applied
fine
organic
synthesis
biotechnology.
For
different
considered,
i.e.
cross-coupling,
cyclization,
carbonylation,
isomerization,
alkylation,
arylation,
Language: Английский
Hybrid Metal Catalysts as Valuable Tools in Organic Synthesis: An Overview of the Recent Advances in Asymmetric C─C Bond Formation Reactions
Molecules,
Journal Year:
2024,
Volume and Issue:
29(21), P. 5090 - 5090
Published: Oct. 28, 2024
Carbon–carbon
bond
formation
represents
a
key
reaction
in
organic
synthesis,
resulting
paramount
importance
for
constructing
the
carbon
backbone
of
molecules.
However,
traditional
metal-based
catalysis,
despite
its
advantages,
often
struggles
with
issues
related
to
efficiency,
selectivity,
and
sustainability.
On
other
hand,
while
biocatalysis
offers
superior
selectivity
due
an
extraordinary
recognition
process
substrate,
scope
applicable
reactions
remains
somewhat
limited.
In
this
context,
Artificial
Metalloenzymes
(ArMs)
Metallo
Peptides
(MPs)
offer
promising
not
fully
explored
solution,
merging
two
fields
transition
metal
catalysis
biotransformations,
by
inserting
catalytically
active
cofactor
into
customizable
protein
scaffold
or
coordinating
ion
directly
short
tunable
amino
acid
(Aa)
sequence,
respectively.
As
result,
these
hybrid
catalysts
have
gained
attention
as
valuable
tools
challenging
catalytic
transformations,
providing
systems
new-to-nature
properties
synthesis.
This
review
overview
recent
advances
development
ArMs
MPs,
focusing
on
their
application
asymmetric
carbon–carbon
bond-forming
reactions,
such
carbene
insertion,
Michael
additions,
Friedel–Crafts
cross-coupling
cyclopropanation,
underscoring
versatility
synthesizing
biologically
relevant
compounds.
Language: Английский
Advancements in Pd-Based Supported Porous Nanocatalysts for the C-C Cross-Coupling Reactions
Catalysts,
Journal Year:
2024,
Volume and Issue:
15(1), P. 16 - 16
Published: Dec. 28, 2024
Palladium
(Pd)
is
a
4d
transition
metal
with
electronic
configuration
[Kr]
4d10
5s0,
and
it
one
of
the
most
widely
studied
metals
in
periodic
table
due
to
its
versatile
catalytic
role
organic
synthesis.
The
choice
ligands
that
can
coordinate
Pd
sites
plays
crucial
progress
reaction.
Due
coexistence
multiple
oxidation
states
(Pd(0)/Pd(II)),
active
catalysts
participate
various
stages
coupling
Pd-catalyzed
C-C
reactions
proceed
through
four
steps:
(1)
oxidative
addition
reactant
site,
(2)
transmetallation,
(3)
rearrangements
ligand
centers
(4)
reductive
elimination
products.
For
heterogeneous
nanocatalysts,
are
often
strongly
bound
(chelated)
solid
catalyst
surfaces.
In
this
review,
we
have
highlighted
advancements
made
nanocatalysts
an
emphasis
on
types
different
classes
porous
solids,
which
could
ligate
via
strong
covalent
bonds.
high
specific
surface
areas
small
these
provide
larger
number
thus
facilitate
Mechanistic
aspects
cross-coupling
discussed
context
structure–reactivity
relationship.
Language: Английский