Differences in Brain Network Topology Based on Alcohol Use History in Adolescents DOI Open Access
Haley Kirse, Mohsen Bahrami, Robert G. Lyday

et al.

Published: Sept. 25, 2023

Approximately 6 million youth aged 12 to 20 consume alcohol monthly in the United States. The effect of consumption adolescence on behavior and cognition is heavily researched, however, little known about how may alter brain function, leading long-term developmental detriments. In order investigate differences connectivity associated with use adolescents, networks were constructed using resting state functional magnetic resonance imaging data collected by National Consortium Alcohol NeuroDevelopment Adolescence (NCANDA) from 698 (12-21 years, 117 hazardous drinkers 581 no/low drinkers). Analyses assessed network topology based eight pre-defined networks, as well whole-brain connectivity. Within central executive (CEN), basal ganglia (BGN), sensorimotor (SMN), demonstrated stronger more frequent connections between highly globally efficient nodes, fewer weaker clustered nodes. Inverse results observed within dorsal attention (DAN), visual (VN), frontotemporal (FTN), demonstrating nodes high efficiency increased frequency compared drinkers. Results this study show clear organizational adolescents or use, suggesting that aberrant these risky drinking behaviors.

Language: Английский

Differences in Brain Network Topology Based on Alcohol Use History in Adolescents DOI Open Access
Haley Kirse, Mohsen Bahrami, Robert G. Lyday

et al.

Published: Sept. 25, 2023

Approximately 6 million youth aged 12 to 20 consume alcohol monthly in the United States. The effect of consumption adolescence on behavior and cognition is heavily researched, however, little known about how may alter brain function, leading long-term developmental detriments. In order investigate differences connectivity associated with use adolescents, networks were constructed using resting state functional magnetic resonance imaging data collected by National Consortium Alcohol NeuroDevelopment Adolescence (NCANDA) from 698 (12-21 years, 117 hazardous drinkers 581 no/low drinkers). Analyses assessed network topology based eight pre-defined networks, as well whole-brain connectivity. Within central executive (CEN), basal ganglia (BGN), sensorimotor (SMN), demonstrated stronger more frequent connections between highly globally efficient nodes, fewer weaker clustered nodes. Inverse results observed within dorsal attention (DAN), visual (VN), frontotemporal (FTN), demonstrating nodes high efficiency increased frequency compared drinkers. Results this study show clear organizational adolescents or use, suggesting that aberrant these risky drinking behaviors.

Language: Английский

Citations

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