Efficacy of Mass Drug Distribution (MDD) in National Schistosomiasis Control Programme Sentinel Sites in Mali DOI Open Access

Dabo Abdoulaye,

Agniwo Privat,

Dante Salim

et al.

Published: Sept. 26, 2023

Background – Mali was one of the first countries in sub-Saharan Africa to initiate a National Schistosomiasis Control Programme (NSCP) 1982. The WHO's 2021-30 roadmap sets out criteria for eliminating and controlling schistosomiasis as public health problem. Our study aimed assess impact annual Mass Drug Distribution (MDD) with praziquantel (PZQ) among school-age children sentinel sites (SS) NSCP. Methods –The took place at twelve SS Kayes Koulikoro regions. Two-round observational cross-sectional studies were carried December 2014-2015 April 2018 after four five years annually MDD. Overall, 2442 schoolchildren aged 7 14 successfully examined. urine filtration Kato-Katz method used determining Schistosoma haematobium S. mansoni eggs, respectively. Results –Of treated from 2014-2015, has achieved criterion elimination problem (prevalence heavy intensity infection PHI < 1%) (ie, ≥50 eggs per 10 mL or ≥400 g stool), met morbidity control (PHI< 5%) while two remained confined below (PHI>5%). Five had no infection. prevalence less than 1%. Conclusion evaluation MDD NSCP highlights that significantly reduced schistosomiasis. However, high its increase some requires in-depth studies.

Language: Английский

Efficacy of Mass Drug Distribution (MDD) in National Schistosomiasis Control Programme Sentinel Sites in Mali DOI Open Access

Dabo Abdoulaye,

Agniwo Privat,

Dante Salim

et al.

Published: Sept. 26, 2023

Background – Mali was one of the first countries in sub-Saharan Africa to initiate a National Schistosomiasis Control Programme (NSCP) 1982. The WHO's 2021-30 roadmap sets out criteria for eliminating and controlling schistosomiasis as public health problem. Our study aimed assess impact annual Mass Drug Distribution (MDD) with praziquantel (PZQ) among school-age children sentinel sites (SS) NSCP. Methods –The took place at twelve SS Kayes Koulikoro regions. Two-round observational cross-sectional studies were carried December 2014-2015 April 2018 after four five years annually MDD. Overall, 2442 schoolchildren aged 7 14 successfully examined. urine filtration Kato-Katz method used determining Schistosoma haematobium S. mansoni eggs, respectively. Results –Of treated from 2014-2015, has achieved criterion elimination problem (prevalence heavy intensity infection PHI < 1%) (ie, ≥50 eggs per 10 mL or ≥400 g stool), met morbidity control (PHI< 5%) while two remained confined below (PHI>5%). Five had no infection. prevalence less than 1%. Conclusion evaluation MDD NSCP highlights that significantly reduced schistosomiasis. However, high its increase some requires in-depth studies.

Language: Английский

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